Zobrazeno 1 - 10
of 801
pro vyhledávání: '"A. C. Gittenberger-de Groot"'
Publikováno v:
The Scientific World Journal, Vol 8, Pp 239-269 (2008)
The cardiac conduction system (CCS) encompasses a complex system responsible for the coordinated contraction of the heart. In the developing heart, as well as in the adult heart, tissues of the (putative) CCS are characterized by different properties
Externí odkaz:
https://doaj.org/article/af20845e04894017afd3fa0e691a1476
Autor:
Joshua C. Peterson, Lambertus J. Wisse, Valerie Wirokromo, Tessa van Herwaarden, Anke M. Smits, Adriana C. Gittenberger-de Groot, Marie-José T. H. Goumans, J. Conny VanMunsteren, Monique R. M. Jongbloed, Marco C. DeRuiter
Publikováno v:
Disease Models & Mechanisms, Vol 13, Iss 9 (2020)
Patients with a congenital bicuspid aortic valve (BAV), a valve with two instead of three aortic leaflets, have an increased risk of developing thoracic aneurysms and aortic dissection. The mechanisms underlying BAV-associated aortopathy are poorly u
Externí odkaz:
https://doaj.org/article/63a376b7ba4e4b439c21b82b9eacdf08
Autor:
Adriana C Gittenberger-de Groot, Joshua C Peterson, Lambertus J Wisse, Arno A W Roest, Robert E Poelmann, Regina Bökenkamp, Nynke J Elzenga, Mark Hazekamp, Margot M Bartelings, Monique R M Jongbloed, Marco C DeRuiter
Publikováno v:
PLoS ONE, Vol 15, Iss 5, p e0228478 (2020)
OBJECTIVES:In congenital heart malformations with pulmonary stenosis to atresia an abnormal lateral ductus arteriosus to left pulmonary artery connection can lead to a localised narrowing (pulmonary ductal coarctation) or even interruption We investi
Externí odkaz:
https://doaj.org/article/97d995e43a3340e7b428c696ec3085d5
Autor:
Robert E. Poelmann, Adriana C. Gittenberger-de Groot, Charissa Goerdajal, Nimrat Grewal, Merijn A. G. De Bakker, Michael K. Richardson
Publikováno v:
Journal of Cardiovascular Development and Disease, Vol 8, Iss 10, p 132 (2021)
Background: The outflow tract of crocodilians resembles that of birds and mammals as ventricular septation is complete. The arterial anatomy, however, presents with a pulmonary trunk originating from the right ventricular cavum, and two aortas origin
Externí odkaz:
https://doaj.org/article/1b57f63537f84e8c878226bf9c0b304a
Publikováno v:
Frontiers in Physiology, Vol 10 (2019)
Externí odkaz:
https://doaj.org/article/6d3b556451f942baa2c7bda1da411d72
Autor:
Nimrat Grewal, Bart J. J. Velders, Adriana C. Gittenberger-de Groot, Robert Poelmann, Robert J. M. Klautz, Thomas J. Van Brakel, Jan H. N. Lindeman
Publikováno v:
Journal of Cardiovascular Development and Disease, Vol 8, Iss 2, p 12 (2021)
(1) Background: The pathophysiologic basis of an acute type A aortic dissection (TAAD) is largely unknown. In an effort to evaluate vessel wall defects, we systematically studied aortic specimens in TAAD patients. (2) Methods: Ascending aortic wall s
Externí odkaz:
https://doaj.org/article/8f7adedca2714adfa2a0c356d7833e57
Autor:
Maria E. Baardman, Mathijs V. Zwier, Lambertus J. Wisse, Adriana C. Gittenberger-de Groot, Wilhelmina S. Kerstjens-Frederikse, Robert M. W. Hofstra, Angelika Jurdzinski, Beerend P. Hierck, Monique R. M. Jongbloed, Rolf M. F. Berger, Torsten Plösch, Marco C. DeRuiter
Publikováno v:
Disease Models & Mechanisms, Vol 9, Iss 4, Pp 413-425 (2016)
Lipoprotein-related receptor protein 2 (LRP2) is important for development of the embryonic neural crest and brain in both mice and humans. Although a role in cardiovascular development can be expected, the hearts of Lrp2 knockout (KO) mice have not
Externí odkaz:
https://doaj.org/article/c075137f727a43e3902cf72dbfd9a1b1
Autor:
Mrinmay Chakrabarti, Nadia Al-Sammarraie, Mengistu G. Gebere, Aniket Bhattacharya, Sunita Chopra, John Johnson, Edsel A. Peña, John F. Eberth, Robert E. Poelmann, Adriana C. Gittenberger-de Groot, Mohamad Azhar
Publikováno v:
Journal of Cardiovascular Development and Disease, Vol 7, Iss 2, p 19 (2020)
Transforming growth factor beta3 (TGFB3) gene mutations in patients of arrhythmogenic right ventricular dysplasia/cardiomyopathy (ARVD1) and Loeys-Dietz syndrome-5 (LDS5)/Rienhoff syndrome are associated with cardiomyopathy, cardiac arrhythmia, cardi
Externí odkaz:
https://doaj.org/article/b498c324be1e4d0d9bdef6d2801a2dc8
Autor:
Joshua C. Peterson, Mary Chughtai, Lambertus J. Wisse, Adriana C. Gittenberger-de Groot, Qingping Feng, Marie-José T. H. Goumans, J. Conny VanMunsteren, Monique R. M. Jongbloed, Marco C. DeRuiter
Publikováno v:
Disease Models & Mechanisms, Vol 11, Iss 10 (2018)
The bicuspid aortic valve (BAV), a valve with two instead of three aortic leaflets, belongs to the most prevalent congenital heart diseases in the world, occurring in 0.5-2% of the general population. We aimed to understand how changes in early cellu
Externí odkaz:
https://doaj.org/article/b02fd22de2a2430990d005bf67bc4e6b
Publikováno v:
Journal of Cardiovascular Development and Disease, Vol 5, Iss 4, p 54 (2018)
The beating heart is subject to intrinsic mechanical factors, exerted by contraction of the myocardium (stretch and strain) and fluid forces of the enclosed blood (wall shear stress). The earliest contractions of the heart occur already in the 10-som
Externí odkaz:
https://doaj.org/article/3d7a286c57da47a0a10b2fcd2d1135c1