Zobrazeno 1 - 10 of 353 pro vyhledávání: '"A. C. Chapple"'
1
Akademický článek
Fusobacterium nucleatum elicits subspecies-specific responses in human neutrophils
Autor: Maria Muchova, Sarah A. Kuehne, Melissa M. Grant, Peter P. Smith, Malee Nagi, Iain L. C. Chapple, Josefine Hirschfeld
Publikováno v: Frontiers in Cellular and Infection Microbiology, Vol 14 (2024)
Fusobacterium nucleatum as a Gram-negative anaerobe plays a key bridging role in oral biofilms. It is involved in periodontal and extraoral diseases, the most prominent being colorectal cancer. Five subspecies are recognised: animalis, fusiforme, nuc
Externí odkaz: https://doaj.org/article/9d664e5d905e4abca8600115ae777dce
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2
Akademický článek
Concordance of three point of care testing devices with clinical chemistry laboratory standard assays and patient-reported outcomes of blood sampling methods
Autor: Z. Yonel, K. Kuningas, P. Sharma, M. Dutton, Z. Jalal, P. Cockwell, J. Webber, P. Narendran, T. Dietrich, I. L. C. Chapple
Publikováno v: BMC Medical Informatics and Decision Making, Vol 22, Iss 1, Pp 1-9 (2022)
Abstract Background Point of care testing (POCT) devices have been developed to facilitate immediate results with the potential to aid screening for new disease and enable patients to self-monitor their disease. Non-communicable diseases (NCDs) are t
Externí odkaz: https://doaj.org/article/3f449980d19b4b03a5dcd475039df18d
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3
Akademický článek
Female Urgency, Trial of Urodynamics as Routine Evaluation (FUTURE study): a superiority randomised clinical trial to evaluate the effectiveness and cost-effectiveness of invasive urodynamic investigations in management of women with refractory overactive bladder symptoms
Autor: M. Abdel-fattah, C. Chapple, K. Guerrero, S. Dixon, N. Cotterill, K. Ward, H. Hashim, A. Monga, K. Brown, M. J. Drake, A. Gammie, A. Mostafa, U. K. Bladder Health, S. Breeman, D. Cooper, G. MacLennan, J. Norrie
Publikováno v: Trials, Vol 22, Iss 1, Pp 1-18 (2021)
Abstract Background Overactive bladder (OAB) syndrome is a symptom complex affecting 12–14% of the UK adult female population. Symptoms include urinary urgency, with or without urgency incontinence, increased daytime urinary frequency and nocturia.
Externí odkaz: https://doaj.org/article/cb9d943bf047458882de3f22afa3625c
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4
Akademický článek
Quorum Sensing in Oral Biofilms: Influence on Host Cells
Autor: Malee Nagi, Iain L. C. Chapple, Praveen Sharma, Sarah A. Kuehne, Josefine Hirschfeld
Publikováno v: Microorganisms, Vol 11, Iss 7, p 1688 (2023)
Quorum sensing molecules (QSMs) in the oral cavity regulate biofilm formation, the acquisition of iron, stress responses, and the expression of virulence factors. However, knowledge of the direct QSM–host interactions in the oral environment is lim
Externí odkaz: https://doaj.org/article/81e18479f25c43b1bf5fed92895c7316
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5
Akademický článek
Patient acceptability of targeted risk-based detection of non-communicable diseases in a dental and pharmacy setting
Autor: Zehra Yonel, Asma Yahyouche, Zahra Jalal, Alistair James, Thomas Dietrich, Iain L. C. Chapple
Publikováno v: BMC Public Health, Vol 20, Iss 1, Pp 1-10 (2020)
Abstract Background Non-communicable diseases [NCDs] are the major cause of mortality globally and are increasing in prevalence. Different healthcare professionals’ access different population groups; and engaging allied healthcare professionals in
Externí odkaz: https://doaj.org/article/cb2d212700224350b1fdc9b9ea64f21d
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6
Akademický článek
Fusobacterium nucleatum Subspecies Differ in Biofilm Forming Ability in vitro
Autor: Maria Muchova, Dario L. Balacco, Melissa M. Grant, Iain L. C. Chapple, Sarah A. Kuehne, Josefine Hirschfeld
Publikováno v: Frontiers in Oral Health, Vol 3 (2022)
Development of dysbiosis in complex multispecies bacterial biofilms forming on teeth, known as dental plaque, is one of the factors causing periodontitis. Fusobacterium nucleatum (F. nucleatum) is recognised as a key microorganism in subgingival dent
Externí odkaz: https://doaj.org/article/bd166c054fe944998a057b86f50d0881
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9
Akademický článek
INfluence of Successful Periodontal Intervention in REnal Disease (INSPIRED): study protocol for a randomised controlled pilot clinical trial
Autor: Praveen Sharma, Paul Cockwell, Thomas Dietrich, Charles Ferro, Natalie Ives, Iain L. C. Chapple
Publikováno v: Trials, Vol 18, Iss 1, Pp 1-10 (2017)
Abstract Background Patients with chronic kidney disease (CKD) exhibit increased morbidity and mortality which is associated with an increased systemic inflammatory burden. Identifying and managing comorbid diseases that contribute to this load may i
Externí odkaz: https://doaj.org/article/79dd56c7cbbb462eb3dc101286b45719
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10
Akademický článek
Oral Neutrophils Characterized: Chemotactic, Phagocytic, and Neutrophil Extracellular Trap (NET) Formation Properties
Autor: Carolyn G. J. Moonen, Josefine Hirschfeld, Lili Cheng, Iain L. C. Chapple, Bruno G. Loos, Elena A. Nicu
Publikováno v: Frontiers in Immunology, Vol 10 (2019)
Maintenance of oral health is in part managed by the immune-surveillance and antimicrobial functions of polymorphonuclear leukocytes (PMNs), which migrate from the circulatory system through the oral mucosal tissues as oral PMNs (oPMNs). In any micro
Externí odkaz: https://doaj.org/article/1b636b7396824ae09d7578c49709b62e
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