Zobrazeno 1 - 10
of 674
pro vyhledávání: '"A. C. McKay"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Activating transcription factor 4 (ATF4) plays a central role in the integrated stress response (ISR) and one overlapping branch of the unfolded protein response (UPR). We recently reported that the splicing inhibitor isoginkgetin (IGG) indu
Externí odkaz:
https://doaj.org/article/f679efd2f57748fdb7b42e9d9ec0a6f5
Autor:
Rama H. G. Mikhail, BBiomedSc, MD, Siobhan C. McKay, DipEd, BMedSci, MBBS, PhD, FRCS, Michael A. Fink, MBBS, MD, FRACS
Publikováno v:
Transplantation Direct, Vol 10, Iss 1, p e1569 (2024)
Externí odkaz:
https://doaj.org/article/7d60546ae1024839bff070060373b284
Publikováno v:
PeerJ, Vol 11, p e16683 (2023)
Background Thapsigargin (Tg) is a compound that inhibits the SERCA calcium transporter leading to decreased endoplasmic reticulum (ER) Ca2+ levels. Many ER chaperones are required for proper folding of membrane-associated and secreted proteins, and t
Externí odkaz:
https://doaj.org/article/a6ace64f6cce496a8a154ec10fac51ba
Autor:
Siobhan C. McKay, Jaswinder S. Samra
Publikováno v:
The Lancet Regional Health. Europe, Vol 31, Iss , Pp 100679- (2023)
Externí odkaz:
https://doaj.org/article/bb42a36b73334dba9b2552f5fe050e15
Autor:
Pandora Hope, Jannatun Nahar, Gen C Tolhurst, Surendra P Rauniyar, Roseanna C McKay, Linjing Zhou, Michael R Grose, Blair C Trewin, David J Martin, Simon Grainger, Avijeet Ramchurn, James S Risbey, David A Jones
Publikováno v:
Environmental Research: Climate, Vol 3, Iss 4, p 045014 (2024)
When a record hot month occurs, timely and credible attribution and contextualisation information can enhance public understanding and future preparedness. This is particularly effective if provided in real time by a National Meteorological and Hydro
Externí odkaz:
https://doaj.org/article/567fab56be2649a0b0693b015c52dd5b
Autor:
Michael Grose, Pandora Hope, James Risbey, Camille J Mora, Sarah Perkins-Kirkpatrick, Andrew King, Luke J Harrington, Suzanne Rosier, Richard Matear, Mitchell Black, Dáithi Stone, David Frame, Roseanna C McKay, Hamish Ramsay, Linjing Zhou, Gen Tolhurst
Publikováno v:
Environmental Research: Climate, Vol 3, Iss 3, p 035009 (2024)
Extreme event attribution (EEA) information is increasingly in demand from climate services. EEA messages can: raise awareness about the effect climate change has already imposed, inform climate change liability conversations, and be combined with cl
Externí odkaz:
https://doaj.org/article/ac567e59277444e58ff8357e004c65d9
Publikováno v:
Weather and Climate Dynamics, Vol 3, Pp 413-428 (2022)
Extreme maximum temperatures during Australian spring can have deleterious impacts on a range of sectors from health to wine grapes to planning for wildfires but are studied relatively little compared to spring rainfall. Spring maximum temperatures i
Externí odkaz:
https://doaj.org/article/e23e9c01e5ce4b0db0308d012f191e97
Autor:
Steven C. McKay, Alberto Ganis, Leslie Lopez, Jennifer Aimee Martinez, Marlen Reyes, Shivani Modha
Publikováno v:
Social Sciences, Vol 12, Iss 6, p 355 (2023)
This article presents findings from a four-year collaborative research project on immigrant and mixed-status families in Santa Cruz County, California. The project employed a new model of critical community-engaged scholarship called Community Initia
Externí odkaz:
https://doaj.org/article/31b4cbd8b3b8486b96903f1e92cccaac
Publikováno v:
Data in Brief, Vol 42, Iss , Pp 108126- (2022)
Isoginkgetin (IGG) is a compound originally derived from the leaves of Ginkgo biloba trees. It was subsequently identified through a chemical screen to be an inhibitor of both the major and minor spliceosome, with an IC50 value of 30 µM [1]. Little
Externí odkaz:
https://doaj.org/article/5793fca4667249e08ac76f4778abef03
Autor:
F. Hoekstra, K. J. Mrklas, M. Khan, R. C. McKay, M. Vis-Dunbar, K. M. Sibley, T. Nguyen, I. D. Graham, SCI Guiding Principles Consensus Panel, H. L. Gainforth
Publikováno v:
Health Research Policy and Systems, Vol 18, Iss 1, Pp 1-23 (2020)
Abstract Background Conducting research in partnership with stakeholders (e.g. policy-makers, practitioners, organisations, patients) is a promising and popular approach to improving the implementation of research findings in policy and practice. Thi
Externí odkaz:
https://doaj.org/article/02ab7b838757406cbad038efd4a6b4ea