Zobrazeno 1 - 10
of 9 859
pro vyhledávání: '"A. C Scott"'
Autor:
Ian C. Scott, Noor Daud, James Bailey, Helen Twohig, Samantha L. Hider, Christian D. Mallen, Kelvin P. Jordan, Sara Muller
Publikováno v:
BMC Medicine, Vol 22, Iss 1, Pp 1-12 (2024)
Abstract Background Gabapentinoids are increasingly prescribed in inflammatory arthritis (IA), despite no trial evidence for efficacy at managing pain in this population. Observational studies in non-IA populations suggest gabapentinoids are associat
Externí odkaz:
https://doaj.org/article/54f1db4b23944ed2842abcd9e9edc55a
Autor:
Daniel C. Scott, Sagar Chittori, Nicholas Purser, Moeko T. King, Samuel A. Maiwald, Kelly Churion, Amanda Nourse, Chan Lee, Joao A. Paulo, Darcie J. Miller, Stephen J. Elledge, J. Wade Harper, Gary Kleiger, Brenda A. Schulman
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Specificity of the ubiquitin-proteasome system depends on E3 ligase-substrate interactions. Many such pairings depend on E3 ligases binding to peptide-like sequences - termed N- or C-degrons - at the termini of substrates. However, our knowl
Externí odkaz:
https://doaj.org/article/1085cb553def4be2ba1ef9f68687d295
Autor:
Maria C. Scott
Publikováno v:
BMC Ophthalmology, Vol 24, Iss 1, Pp 1-6 (2024)
Abstract Background To evaluate procedure times for two cataract planning systems (ZEISS CALLISTO eye and the Wavetec AnalyzOR) in predicting residual astigmatism (prediction error) and other visual outcomes in patients with corneal astigmatism (maxi
Externí odkaz:
https://doaj.org/article/8081473c684649e091ccb37a448426bf
Autor:
Angela Wangari Walter, Minu P. Mohan, Xiyuan Zhang, Melanie Rocco, Serena Rajabiun, Howard J. Cabral, Clara A. Chen, Esther Jennings, Julianne N. Dugas, Talitha Dantas, Judith C. Scott, Alicia Downes, Linda S. Sprague Martinez
Publikováno v:
BMC Health Services Research, Vol 24, Iss 1, Pp 1-15 (2024)
Abstract Background Evidence-based and evidence-informed interventions designed to address gaps in the HIV care continuum have the potential to improve HIV care and treatment. However, inadequate organizational readiness can derail intervention uptak
Externí odkaz:
https://doaj.org/article/6a4450c8c3334e5a99a5958cea5e1759
Autor:
Daniel C. Scott, Suresh Dharuman, Elizabeth Griffith, Sergio C. Chai, Jarrid Ronnebaum, Moeko T. King, Rajendra Tangallapally, Chan Lee, Clifford T. Gee, Lei Yang, Yong Li, Victoria C. Loudon, Ha Won Lee, Jason Ochoada, Darcie J. Miller, Thilina Jayasinghe, Joao A. Paulo, Stephen J. Elledge, J. Wade Harper, Taosheng Chen, Richard E. Lee, Brenda A. Schulman
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract PROTAC® (proteolysis-targeting chimera) molecules induce proximity between an E3 ligase and protein-of-interest (POI) to target the POI for ubiquitin-mediated degradation. Cooperative E3-PROTAC-POI complexes have potential to achieve neo-su
Externí odkaz:
https://doaj.org/article/6c50c513c918469eaf4c94f0f0e0d58b
Autor:
Melanie Rocco, Madison Kitchen, Cecilia Flores-Rodriguez, Alicia Downes, Judith C. Scott, Serena Rajabiun, Angela Wangari Walter, Linda Sprague Martinez
Publikováno v:
Implementation Science Communications, Vol 5, Iss 1, Pp 1-8 (2024)
Abstract Background The Expert Recommendations for Implementing Change (ERIC) project identified 73 strategies for supporting the implementation of a novel intervention and evidence-informed practices. In this paper, we explore convenings, which enga
Externí odkaz:
https://doaj.org/article/703a85f8fed141188a801f04dd591cd8
Autor:
Laura Moliner, MD, Núria Zellweger, MSc, Sabine Schmid, MD, Martina Bertschinger, MD, Christine Waibel, MD, Ferdinando Cerciello, MD, PhD, Patrizia Froesch, MD, Michael Mark, MD, Adrienne Bettini, MD, Pirmin Häuptle, MD, Veronika Blum, MD, Lisa Holer, MSc, Stefanie Hayoz, PhD, Martin Früh, MD, Samreen Ahmed, FRCP, MD, MBBS, MSc, Shradha Bhagani, MD, Nicola Steele, MD, Hannah-Leigh Gray, BSc, Stephen D. Robinson, MD, Michael Davidson, MD (Res), Samantha Cox, MD, MSc, MBBCh, Taha Khalid, MD, Tom R. Geldart, MD, Luke Nolan, FRCS, PhD, Deborah C. Scott, MBChB (MRCP), Lindsay Hennah, MD, Tom Newsom-Davis, MD, PhD, Emma Rathbone, MD, PhD, Catherine Handforth, MD, Arshi Denton, MD, Shairoz Merchant, PhD, Fiona Blackhall, MD, PhD, Laetitia A. Mauti, MD, Raffaele Califano, MD, Sacha I. Rothschild, MD, PhD
Publikováno v:
JTO Clinical and Research Reports, Vol 6, Iss 1, Pp 100744- (2025)
Introduction: SCLC is characterized by aggressiveness and limited treatment options, especially in extensive-stage SCLC (ES-SCLC). Immunotherapy added to the platinum-etoposide combination has recently become standard in this setting. This retrospect
Externí odkaz:
https://doaj.org/article/4fc33687ab8d4162bfd96a7cd9362df2
Publikováno v:
Poultry Science, Vol 103, Iss 12, Pp 104356- (2024)
ABSTRACT: Chickens in Australia have recently been identified with symptoms and morphological findings including spondylitis attributed to pathogenic Enterococcus cecorum. Notably, there is limited information on clinical E. cecorum strains in Austra
Externí odkaz:
https://doaj.org/article/18d0d03e81e24653a114dd35889fb053
Autor:
Christina A. Ahlstrom, Mia Kim Torchetti, Julianna Lenoch, Kimberlee Beckmen, Megan Boldenow, Evan J. Buck, Bryan Daniels, Krista Dilione, Robert Gerlach, Kristina Lantz, Angela Matz, Rebecca L. Poulson, Laura C. Scott, Gay Sheffield, David Sinnett, David E. Stallknecht, Raphaela Stimmelmayr, Eric Taylor, Alison R. Williams, Andrew M. Ramey
Publikováno v:
Emerging Microbes and Infections, Vol 13, Iss 1 (2024)
The ongoing panzootic of highly pathogenic H5 clade 2.3.4.4b avian influenza (HPAI) spread to North America in late 2021, with detections of HPAI viruses in Alaska beginning in April 2022. HPAI viruses have since spread across the state, affecting ma
Externí odkaz:
https://doaj.org/article/0faf71f541e047ebb42bfecadff441aa
Autor:
Cody R. DeHaan, Emma L. Bradshaw, Sandra Diaz-Castillo, Todd C. Trautman, C. Scott Rigby, Richard M. Ryan
Publikováno v:
Frontiers in Psychology, Vol 15 (2024)
In this study, we expanded upon the job demands–resources model to assess the role of employees’ vitality as an inner resource for their work engagement and job commitment. To assess vitality and related job resources, we developed an index of vi
Externí odkaz:
https://doaj.org/article/20238135e6f44b73970e46628b1ad051