Zobrazeno 1 - 10
of 124
pro vyhledávání: '"A. C F Caires"'
Autor:
Julian E. Muñoz, Diego C. P. Rossi, Kelly Ishida, Cristina C. Spadari, Marcia S. C. Melhem, Daniel M. Garcia, Antonio C. F. Caires, Carlos P. Taborda, Elaine G. Rodrigues
Publikováno v:
Frontiers in Microbiology, Vol 8 (2017)
Vulvovaginal and invasive candidiasis are frequent conditions in immunosuppressed individuals caused by Candida albicans and non-albicans Candida spp. Fluconazole and Amphotericin B are the main drugs used to fight the infection. However, resistance
Externí odkaz:
https://doaj.org/article/d4ef332fa5294d02996b19bf88503301
Autor:
Carolina de Siqueira Paladi, Isabella Aparecida Salerno Pimentel, Simone Katz, Rodrigo L O R Cunha, Wagner Alves de Souza Judice, Antonio C F Caires, Clara Lúcia Barbiéri
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 6, Iss 5, p e1626 (2012)
BACKGROUND: Antitumor cyclopalladated complexes with low toxicity to laboratory animals have shown leishmanicidal effect. These findings stimulated us to test the leishmanicidal property of one palladacycle compound called DPPE 1.2 on Leishmania (Lei
Externí odkaz:
https://doaj.org/article/6efaacbcc2d04aa399eac937c25fdd91
Autor:
Rafael Gigli, Fernanda Antunes, Claudia Bincoletto, Antonio C. F. Caires, Alexandre Bechara, Soraya S. Smaili, Gustavo J.S. Pereira, Daniel M. Garcia, Daniel G. Spindola, Mirian G. Jasiulionis
Publikováno v:
European Journal of Medicinal Chemistry. 107:245-254
Recently, palladium complexes have been extensively studied as cyclization of these complexes by cyclometallation reactions increased their stability making them promising antitumor compounds. In this study, we have investigated apoptosis induced by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d156892efd684d6e45d97025efd7b49
https://doi.org/10.1016/j.ejmech.2015.11.008
https://doi.org/10.1016/j.ejmech.2015.11.008
Autor:
Larissa V. G. Longo, Fernanda F. M. Cunha, Natanael P. Leitão, Daniel M. Garcia, Antonio C. F. Caires, Denise C. Arruda, Luiz S. Silva, Rosana Puccia, Alisson L. Matsuo, Jhon H. S. Pires, Fernando Real
Publikováno v:
Antimicrobial Agents and Chemotherapy
Antimicrobial Agents and Chemotherapy, 2015, 59 (12), pp.7214-7223. ⟨10.1128/AAC.00512-15⟩
Antimicrobial Agents and Chemotherapy, 2015, 59 (12), pp.7214-7223. ⟨10.1128/AAC.00512-15⟩
Paracoccidioidomycosis (PCM), caused by Paracoccidioides species, is the main cause of death due to systemic mycoses in Brazil and other Latin American countries. Therapeutic options for PCM and other systemic mycoses are limited and time-consuming,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d2030597291f8e49e01864a82bc4430
https://doi.org/10.1128/aac.00512-15
https://doi.org/10.1128/aac.00512-15
Publikováno v:
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Universidade de São Paulo (USP)
instacron:USP
The simple halogenation of alkynes in conventional organic reactions gives a blend of cis and trans isomers. It is proposed then, a synthesis of stereospecific halogenation of alkynes in trans position, using palladacycle as intermediaries. The recry
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9fb9c205e129d6dfde6df9005621a8c9
https://doi.org/10.1016/j.molstruc.2010.12.029
https://doi.org/10.1016/j.molstruc.2010.12.029
Autor:
Tiago Rodrigues, Iseli L. Nantes, Rodrigo L. O. R. Cunha, César H. Yokomizo, Antonio C. F. Caires, Débora P. Santana, Felipe S. Pessoto, Carolina G. dos Santos, Priscila A. Faria, Juliana C. Araujo-Chaves
Publikováno v:
Journal of Bioenergetics and Biomembranes. 43:11-18
In this minireview, the more recent findings about the effects of peculiar reactive thiol drugs on mitochondria are presented. These include the following compounds: metallo meso-tetrakis porphyrins, palladacycles, telluranes and phenothiazines. Meta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c18441a613bb73875cb0e3eb38e9ee69
https://doi.org/10.1007/s10863-011-9328-9
https://doi.org/10.1007/s10863-011-9328-9
Autor:
Claudia Bincoletto, Rodrigo L. O. R. Cunha, João V. Comasseto, Mary L.S. Queiroz, C.M.V. Barbosa, Antonio C. F. Caires, F.E.G. Pereira, T.S. Abondanza, Carlos R. Oliveira, Marize Campos Valadares
Publikováno v:
Food and Chemical Toxicology. 46:2540-2545
Organotellurium(IV) compounds have been reported to have multiple biological activities including cysteine protease-inhibitory activity, mainly cathepsin B. As cathepsin B is a highly predictive indicator for prognosis and diagnosis of cancer, a poss
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1f738200197a938f82ccc2f605e61c0
https://doi.org/10.1016/j.fct.2008.04.010
https://doi.org/10.1016/j.fct.2008.04.010
Autor:
Antonio C. F. Caires
Publikováno v:
Anti-Cancer Agents in Medicinal Chemistry. 7:484-491
This review deals with the most important results published on the structures, reactivity and biomedical applications of palladium( II) complexes in the cancer therapy in the last five years. Biological mechanisms of palladium(II) complexes, especial
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1e251fc2618c4e40cac4574ae6fea9a
https://doi.org/10.2174/187152007781668661
https://doi.org/10.2174/187152007781668661
Autor:
Marco Antônio Soufen, Ivarne L.S. Tersariol, C.M.V. Barbosa, Ronaldo C. Araujo, Mickaela C. M. Smith, Carlos R. Oliveira, Claudia Bincoletto, Daniela M. Fausto, Fabio D. Nascimento, Eliana Sena, Antonio C. F. Caires
Publikováno v:
European Journal of Pharmacology. 542:37-47
The cell death mechanism of cytotoxicity induced by the Biphosphinic Palladacycle Complex (BPC) was studied using a K562 leukaemia cell line. The IC50 values obtained for K562 cells post-72 h of BPC were less than 5.0 microM by using 3-[4,5-dimethylt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d75b6080eafdf10efe2ff227e8f3cf7
https://doi.org/10.1016/j.ejphar.2006.06.004
https://doi.org/10.1016/j.ejphar.2006.06.004
Autor:
Luis Silva, Soraya S. Smaili, Alexandre Bechara, Daniel M. Garcia, Fabio D. Nascimento, Claudia Bincoletto, Edgar J. Paredes-Gamero, Antonio C. F. Caires, Elaine G. Rodrigues, Christiano M.V. Barbosa, Alisson L. Matsuo
Publikováno v:
European journal of medicinal chemistry. 79
The search for new compounds that induce p53-independent apoptosis is the focus of many studies in cancer biology because these compounds could be more specific and would overcome chemotherapy resistance. In this study, we evaluated the in vitro anti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2cd5f8b557f14a5a3052fe2aefe5570
https://pubmed.ncbi.nlm.nih.gov/24709226
https://pubmed.ncbi.nlm.nih.gov/24709226