Zobrazeno 1 - 10
of 196
pro vyhledávání: '"A. Bruce Lyons"'
Autor:
Chrissie E. B. Ong, Yuanyuan Cheng, Hannah V. Siddle, A. Bruce Lyons, Gregory M. Woods, Andrew S. Flies
Publikováno v:
Open Biology, Vol 12, Iss 10 (2022)
MHC-I and MHC-II molecules are critical components of antigen presentation and T cell immunity to pathogens and cancer. The two monoclonal transmissible devil facial tumours (DFT1, DFT2) exploit MHC-I pathways to overcome immunological anti-tumour an
Externí odkaz:
https://doaj.org/article/9cf22af03f78459993435df2140aef2c
Autor:
Camila Espejo, Richard Wilson, Ruth J. Pye, Julian C. Ratcliffe, Manuel Ruiz-Aravena, Eduard Willms, Barrett W. Wolfe, Rodrigo Hamede, Andrew F. Hill, Menna E. Jones, Gregory M. Woods, A. Bruce Lyons
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
The identification of practical early diagnostic biomarkers is a cornerstone of improved prevention and treatment of cancers. Such a case is devil facial tumor disease (DFTD), a highly lethal transmissible cancer afflicting virtually an entire specie
Externí odkaz:
https://doaj.org/article/deb9074387af4ce3bc81e9b342b80867
Publikováno v:
Pathogens, Vol 11, Iss 1, p 27 (2021)
Devil Facial Tumour Disease (DFTD) is an emerging infectious disease that provides an excellent example of how diagnostic techniques improve as disease-specific knowledge is generated. DFTD manifests as tumour masses on the faces of Tasmanian devils,
Externí odkaz:
https://doaj.org/article/065f88848f66454ebd48f21d3ff00397
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Macrophages have emerged as a key component of the innate immune system that emigrates to peripheral tissues during gestation and in the adult organism. Their complex pathway to maturity, their unique plasticity and their various roles as effector an
Externí odkaz:
https://doaj.org/article/8571cbf7ce144dd1aff4e34fccd5e0ba
Publikováno v:
Tropical Medicine and Infectious Disease, Vol 5, Iss 2, p 50 (2020)
Devil facial tumor disease (DFTD) encompasses two independent transmissible cancers that have killed the majority of Tasmanian devils. The cancer cells are derived from Schwann cells and are spread between devils during biting, a common behavior duri
Externí odkaz:
https://doaj.org/article/68f2ae3207834a92a5b2aeb52b2d0396
Autor:
Ruth Pye, Amanda Patchett, Elspeth McLennan, Russell Thomson, Scott Carver, Samantha Fox, David Pemberton, Alexandre Kreiss, Adriana Baz Morelli, Anabel Silva, Martin J. Pearse, Lynn M. Corcoran, Katherine Belov, Carolyn J. Hogg, Gregory M Woods, A. Bruce Lyons
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Devil facial tumor disease (DFTD) is renowned for its successful evasion of the host immune system. Down regulation of the major histocompatabilty complex class I molecule (MHC-I) on the DFTD cells is a primary mechanism of immune escape. Immunizatio
Externí odkaz:
https://doaj.org/article/1a1f2541ab124f31a430c530599a79e5
Publikováno v:
Methods in Molecular Biology ISBN: 9781071629772
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0add772c3e784127ad7f01d43ca46960
https://doi.org/10.1007/978-1-0716-2978-9_9
https://doi.org/10.1007/978-1-0716-2978-9_9
Autor:
Ruth Pye, Jocelyn Darby, Andrew S. Flies, Samantha Fox, Scott Carver, Jodie Elmer, Kate Swift, Carolyn Hogg, David Pemberton, Gregory Woods, A. Bruce Lyons
Publikováno v:
Wildlife Research. 48:701-712
Context Disease is increasingly becoming a driver of wildlife population declines and an extinction risk. Vaccines are one of the most successful health interventions in human history, but few have been tested for mitigating wildlife disease. The tra
Publikováno v:
Pathogens, Vol 11, Iss 27, p 27 (2022)
Pathogens
Pathogens
Devil Facial Tumour Disease (DFTD) is an emerging infectious disease that provides an excellent example of how diagnostic techniques improve as disease-specific knowledge is generated. DFTD manifests as tumour masses on the faces of Tasmanian devils,
Autor:
Eduard Willms, Menna E. Jones, Ruth J. Pye, Camila Espejo, Manuel Ruiz-Aravena, Andrew F. Hill, Richard Wilson, Gregory M. Woods, A. Bruce Lyons
Publikováno v:
Cellular and Molecular Life Sciences. 78:7537-7555
The iconic Tasmanian devil (Sarcophilus harrisii) is endangered due to the transmissible cancer Devil Facial Tumour Disease (DFTD), of which there are two genetically independent subtypes (DFT1 and DFT2). While DFT1 and DFT2 can be differentially dia