Zobrazeno 1 - 10
of 23
pro vyhledávání: '"A. Brianne Thrush"'
Autor:
Ewa Soltysinska, Bo Hjorth Bentzen, Maria Barthmes, Helle Hattel, A Brianne Thrush, Mary-Ellen Harper, Klaus Qvortrup, Filip J Larsen, Tomas A Schiffer, Jose Losa-Reyna, Julia Straubinger, Angelina Kniess, Morten Bækgaard Thomsen, Andrea Brüggemann, Stefanie Fenske, Martin Biel, Peter Ruth, Christian Wahl-Schott, Robert Christopher Boushel, Søren-Peter Olesen, Robert Lukowski
Publikováno v:
PLoS ONE, Vol 9, Iss 7, p e103402 (2014)
Mitochondrial potassium channels have been implicated in myocardial protection mediated through pre-/postconditioning. Compounds that open the Ca2+- and voltage-activated potassium channel of big-conductance (BK) have a pre-conditioning-like effect o
Externí odkaz:
https://doaj.org/article/dbbff612b11847458ebf93062fcaf03b
Autor:
A. Brianne Thrush, Denuja Karunakaran, Ljubica Perisic, Prakriti Shangari, Mireille Ouimet, Michele Geoffrion, Ulf Hedin, John Paul Pezacki, Katey J. Rayner, My-Anh Nguyen, Kathryn J. Moore, Mary-Ellen Harper, Lars Maegdefessel, Laura M. Richards, Eleni Ramphos, Ragunath Singaravelu
Publikováno v:
Circulation Research. 117:266-278
Rationale: Therapeutically targeting macrophage reverse cholesterol transport is a promising approach to treat atherosclerosis. Macrophage energy metabolism can significantly influence macrophage phenotype, but how this is controlled in foam cells is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43ea1ff02d09c2da87daaa44088e904d
https://doi.org/10.1161/circresaha.117.305624
https://doi.org/10.1161/circresaha.117.305624
Autor:
David C. Wright, Bruce C. Frier, Zhongxiao Wan, A. Brianne Thrush, Lindsey Sutherland, Deon B. Williams, Melanie Legare
Publikováno v:
American Journal of Physiology-Cell Physiology. 299:C1162-C1170
Fatty acid reesterification in adipose tissue is dependent on the generation of glycerol 3-phosphate, and, at least in rodent adipose tissue, this appears to occur primarily through glyceroneogenesis. A key enzyme in this process is pyruvate dehydrog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6f5d64198d4bb9e7a11da4858522eaa
https://doi.org/10.1152/ajpcell.00188.2010
https://doi.org/10.1152/ajpcell.00188.2010
Autor:
George J. F. Heigenhauser, Adrian Chabowski, David N. Brindley, A. Brianne Thrush, David J. Dyck
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 94:5053-5061
Context: Skeletal muscle lipid content is increased in obesity. Recent evidence suggests that fatty acid (FA) storage as triacylglycerol (TAG) represents a metabolically safe pool compared to the more bioactive diacylglycerol (DAG) and ceramide.Objec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eaf6b532cea68be6c1a60da0dec6807f
https://doi.org/10.1210/jc.2008-2565
https://doi.org/10.1210/jc.2008-2565
Publikováno v:
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 296:R944-R951
Resistin is a cytokine implicated in the development of insulin resistance. However, there has been little investigation of the effects of resistin on fatty acid (FA) metabolism and insulin response in skeletal muscle, a key tissue for glucose dispos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6577fbd56f7ed35c776e7f65a0f57120
https://doi.org/10.1152/ajpregu.90971.2008
https://doi.org/10.1152/ajpregu.90971.2008
Autor:
Arend Bonen, A. Brianne Thrush, Graham P. Holloway, David J. Dyck, Christopher G. R. Perry, Lawrence L. Spriet, George J. F. Heigenhauser
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism. 294:E1060-E1069
Reduced skeletal muscle mitochondrial content and fatty acid oxidation are associated with obesity and insulin resistance. Although the exact mechanisms remain elusive, this may result from impaired mitochondrial biogenesis or reductions in the mitoc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62f8860da0031cf49e8fc7166ab742b0
https://doi.org/10.1152/ajpendo.00726.2007
https://doi.org/10.1152/ajpendo.00726.2007
Autor:
Narendra N. Tandon, Arend Bonen, A. Brianne Thrush, David J. Dyck, Graham P. Holloway, George J. F. Heigenhauser, Lawrence L. Spriet
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism. 292:E1782-E1789
A reduction in fatty acid oxidation has been associated with lipid accumulation and insulin resistance in the skeletal muscle of obese individuals. We examined whether this decrease in fatty acid oxidation was attributable to a reduction in muscle mi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10b24e6878439c529f54636efbf41e7e
https://doi.org/10.1152/ajpendo.00639.2006
https://doi.org/10.1152/ajpendo.00639.2006
Autor:
David J. Dyck, George J. HeigenhauserG.J. Heigenhauser, A. Brianne Thrush, Adrian Chabowski, Mamun Or-RashidM. Or-Rashid, Brian W. McBride
Publikováno v:
Applied Physiology, Nutrition, and Metabolism. 32:372-382
The effect of conjugated linoleic acid (CLA), a popular weight-loss supplement, on insulin sensitivity in humans is controversial and has notbeen extensively studied. To date no studies have examined the effects of CLA supplementation on human skelet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc2f4177e597147a6286e1f01aa1e7bd
https://doi.org/10.1139/h06-116
https://doi.org/10.1139/h06-116
Autor:
Ruth McPherson, Alyssa C. Peixoto, Ruth S. Slack, Fiona McMurray, David A. Patten, Ghadi Antoun, Mary-Ellen Harper, Robert Dent, A. Brianne Thrush
Publikováno v:
Diabetologia. 58(12)
Skeletal muscle mitochondrial dysfunction has been documented in patients with type 2 diabetes mellitus; however, specific respiratory defects and their mechanisms are poorly understood. The aim of the current study was to examine oxidative phosphory
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d25d4685ef7e9d07a8f69eb05bb53244
https://pubmed.ncbi.nlm.nih.gov/26610932
https://pubmed.ncbi.nlm.nih.gov/26610932
Autor:
Nathan McIntosh, A. Brianne Thrush, Mary-Elizabeth Patti, Mary-Ellen Harper, Ghadi Antoun, Brittany Beauchamp, Jessica K. Quizi, Osama Y. Al-Dirbashi
Publikováno v:
Bioscience Reports
We show that in utero undernutrition is associated with impaired cardiac muscle energetics and increased plasma short-chain acylcarnitines in adult mice. Findings suggest that in utero undernutrition is associated with maladaptive programming process
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f64bffb47434898f70f18fff115ad202
https://pubmed.ncbi.nlm.nih.gov/26182362
https://pubmed.ncbi.nlm.nih.gov/26182362