Zobrazeno 1 - 10
of 8 811
pro vyhledávání: '"A. Boonen"'
Autor:
N. F. Bakker, S. F. E. van Weely, N. Hutting, Y. F. Heerkens, J. A. Engels, J. B. Staal, M. van der Leeden, A. Boonen, W. B. van den Hout, T. P. M. Vliet Vlieland, J. Knoop
Publikováno v:
BMC Rheumatology, Vol 7, Iss 1, Pp 1-13 (2023)
Abstract Background Although reduced work ability is a substantial problem among people with inflammatory arthritis (IA), work ability is an underexposed area in clinical practice. Evidence on vocational interventions in IA is limited, but favourable
Externí odkaz:
https://doaj.org/article/d8bbbea4a4874047ad062c67439691e2
This paper considers an insurance company that faces two key constraints: a ratcheting dividend constraint and an irreversible reinsurance constraint. The company allocates part of its reserve to pay dividends to its shareholders while strategically
Externí odkaz:
http://arxiv.org/abs/2408.16989
This paper explores optimal insurance solutions based on the Lambda-Value-at-Risk ($\Lambda\VaR$). If the expected value premium principle is used, our findings confirm that, similar to the VaR model, a truncated stop-loss indemnity is optimal in the
Externí odkaz:
http://arxiv.org/abs/2408.09799
Autor:
Boonen, Tim J., Han, Xia
This paper studies an optimal insurance contracting problem in which the preferences of the decision maker given by the sum of the expected loss and a convex, increasing function of a deviation measure. As for the deviation measure, our focus is on c
Externí odkaz:
http://arxiv.org/abs/2312.01813
Autor:
B. Spaetgens, F. de Vries, J. H. M. Driessen, H. G. Leufkens, P. C. Souverein, A. Boonen, J. W. M. van der Meer, L. A. B. Joosten
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-9 (2017)
Abstract To investigate the risk of various types of infections (pneumonia and urinary tract infection (UTI)), and infection-related mortality in patients with gout compared with population-based controls. A retrospective cohort study was conducted u
Externí odkaz:
https://doaj.org/article/64a0bd9de8ec464d91a90a6c58524434
Publikováno v:
JEADV Clinical Practice, Vol 3, Iss 2, Pp 547-564 (2024)
Abstract Background Psoriasis, a common chronic inflammatory skin disease with major impact on quality of life, is associated with several comorbidities. A better understanding of the pathogenesis of psoriasis has led to the development and approval
Externí odkaz:
https://doaj.org/article/08fc66fd6dfa49bebc68b3e59ddcb913
Autor:
Suzanne E. de Bruijn, Daan M. Panneman, Nicole Weisschuh, Elizabeth L. Cadena, Erica G. M. Boonen, Lara K. Holtes, Galuh D. N. Astuti, Frans P. M. Cremers, Nico Leijsten, Jordi Corominas, Christian Gilissen, Anna Skowronska, Jessica Woodley, Andrew D. Beggs, Vasileios Toulis, Di Chen, Michael E. Cheetham, Alison J. Hardcastle, Terri L. McLaren, Tina M. Lamey, Jennifer A. Thompson, Fred K. Chen, John N. de Roach, Isabella R. Urwin, Lori S. Sullivan, Susanne Roosing
Publikováno v:
Frontiers in Genetics, Vol 15 (2024)
IntroductionAutosomal dominant retinitis pigmentosa type 17 (adRP, type RP17) is caused by complex structural variants (SVs) affecting a locus on chromosome 17 (chr17q22). The SVs disrupt the 3D regulatory landscape by altering the topologically asso
Externí odkaz:
https://doaj.org/article/4befa15848f34806ac97263fee8b70c9
Autor:
Tabea V. Riepe, Merel Stemerdink, Renee Salz, Alfredo Dueñas Rey, Suzanne E. de Bruijn, Erica Boonen, Tomasz Z. Tomkiewicz, Michael Kwint, Jolein Gloerich, Hans J. C. T. Wessels, Emma Delanote, Elfride De Baere, Filip van Nieuwerburgh, Sarah De Keulenaer, Barbara Ferrari, Stefano Ferrari, Frauke Coppieters, Frans P. M. Cremers, Erwin van Wyk, Susanne Roosing, Erik de Vrieze, Peter A. C. ‘t Hoen
Publikováno v:
Frontiers in Genetics, Vol 15 (2024)
The human neural retina is a complex tissue with abundant alternative splicing and more than 10% of genetic variants linked to inherited retinal diseases (IRDs) alter splicing. Traditional short-read RNA-sequencing methods have been used for understa
Externí odkaz:
https://doaj.org/article/597f13c9088a47f6afda9d373f062809
Autor:
Kashnitsky, Yury, Roberge, Guillaume, Mu, Jingwen, Kang, Kevin, Wang, Weiwei, Vanderfeesten, Maurice, Rivest, Maxim, Chamezopoulos, Savvas, Jaworek, Robert, Vignes, Maéva, Jayabalasingham, Bamini, Boonen, Finne, James, Chris, Doornenbal, Marius, Labrosse, Isabelle
The United Nations (UN) Sustainable Development Goals (SDGs) challenge the global community to build a world where no one is left behind. Recognizing that research plays a fundamental part in supporting these goals, attempts have been made to classif
Externí odkaz:
http://arxiv.org/abs/2209.07285
Autor:
Charlotte Adams, Wassim Gabriel, Kris Laukens, Mario Picciani, Mathias Wilhelm, Wout Bittremieux, Kurt Boonen
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-11 (2024)
Abstract Immunopeptidomics is crucial for immunotherapy and vaccine development. Because the generation of immunopeptides from their parent proteins does not adhere to clear-cut rules, rather than being able to use known digestion patterns, every pos
Externí odkaz:
https://doaj.org/article/a40d30a2d0b94b5f98ca6b246be6cccf