Zobrazeno 1 - 10
of 159
pro vyhledávání: '"A. Berkenstam"'
Autor:
Fahmi Mesmar, Bingbing Dai, Ahmed Ibrahim, Linnea Hases, Mohammed Hakim Jafferali, Jithesh Jose Augustine, Sebastian DiLorenzo, Ya'an Kang, Yang Zhao, Jing Wang, Michael Kim, Chin‐Yo Lin, Anders Berkenstam, Jason Fleming, Cecilia Williams
Publikováno v:
Cancer Medicine, Vol 8, Iss 18, Pp 7705-7719 (2019)
Abstract Despite advances in cancer therapeutics, pancreatic cancer remains difficult to treat and often develops resistance to chemotherapies. We have evaluated a bioavailable genistein analogue, AXP107‐11 which has completed phase Ib clinical tri
Externí odkaz:
https://doaj.org/article/900afa4941d14028b0d39be55bc5e75d
Autor:
Bertilsson, Goran, Heidrich, Jessica, Svensson, Kristian, Asman, Michael, Jendeberg, Lena, Sydow-Backman, Mona, Ohlsson, Rolf, Postlind, Hans, Blomquist, Patrik, Berkenstam, Anders
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 1998 Oct . 95(21), 12208-12213.
Externí odkaz:
https://www.jstor.org/stable/46038
Autor:
Löhr, Johannes-Matthias, Karimi, Masoud, Omazic, Brigitta, Kartalis, Nikolaos, Verbeke, Caroline Sabine, Berkenstam, Anders, Frödin, Jan-Erik
Publikováno v:
In Pancreatology July-August 2016 16(4):640-645
Autor:
Berkenstam, Anders, Kristensen, Jens, Mellström, Karin, Carlsson, Bo, Malm, Johan, Rehnmark, Stefan, Garg, Neeraj, Andersson, Carl Magnus, Rudling, Mats, Sjöberg, Folke, Angelin, Bo, Baxter, John D.
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 2008 Jan . 105(2), 663-667.
Externí odkaz:
https://www.jstor.org/stable/25451147
Publikováno v:
In Current Opinion in Pharmacology 2005 5(2):171-176
Akademický článek
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Publikováno v:
European Journal of Biochemistry. 269:4896-4904
The cytochrome P450 family of enzymes has long been known to metabolize a wide range of compounds, including many of today's most common drugs. A novel nuclear receptor called PXR has been established as an activator of several of the cytochrome P450
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5e7b14ff1596f23d7150b3e897348bc2
https://doi.org/10.1046/j.1432-1033.2002.03207.x
https://doi.org/10.1046/j.1432-1033.2002.03207.x
Autor:
Xiaohua Lou, Rosa A. Villagomez, Paul Webb, Jan-Åke Gustafsson, Cindy Benod, Carly S. Filgueira, Anders Ström, Prem S. Gunamalai, Anders L. Berkenstam
Publikováno v:
Nuclear Receptor Signaling
The establishment of effective high throughput screening cascades to identify nuclear receptor (NR) ligands that will trigger defined, therapeutically useful sets of NR activities is of considerable importance. Repositioning of existing approved drug
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd532e87aebadd302a1c36d7d0c7c527
https://pubmed.ncbi.nlm.nih.gov/25422593
https://pubmed.ncbi.nlm.nih.gov/25422593
Autor:
Anders Berkenstam, Lorenz Poellinger, Göran Bertilsson, Yihai Cao, Yuichi Makino, Kristian Svensson, Renhai Cao, Mikael Asman, Hirotoshi Tanaka
Publikováno v:
Nature. 414:550-554
Alteration of gene expression is a crucial component of adaptive responses to hypoxia. These responses are mediated by hypoxia-inducible transcription factors (HIFs)1,2. Here we describe an inhibitory PAS (Per/Arnt/Sim) domain protein, IPAS, which is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c8e0bb8e633f09284e19a56efb25ab4
https://doi.org/10.1038/35107085
https://doi.org/10.1038/35107085
Autor:
Mona Sydow-Bäckman, Anders Berkenstam, Göran Bertilsson, Patrik Blomquist, Rolf Ohlsson, Hans Postlind, Lena Jendeberg, Michael Åsman, Kristian Svensson, Jessica Heidrich
Publikováno v:
Proceedings of the National Academy of Sciences. 95:12208-12213
Nuclear receptors regulate metabolic pathways in response to changes in the environment by appropriate alterations in gene expression of key metabolic enzymes. Here, a computational search approach based on iteratively built hidden Markov models of n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ff36ef32c5a88c744dfbdf09ecca8a9
https://doi.org/10.1073/pnas.95.21.12208
https://doi.org/10.1073/pnas.95.21.12208