The sGC Activator Runcaciguat Has Kidney Protective Effects and Prevents a Decline of Kidney Function in ZSF1 Rats.

Autor: Kraehling, Jan R.¹ (AUTHOR), Benardeau, Agnes^1,2 (AUTHOR), Schomber, Tibor^1,3 (AUTHOR), Popp, Laura¹ (AUTHOR), Vienenkoetter, Julia¹ (AUTHOR), Ellinger-Ziegelbauer, Heidrun¹ (AUTHOR), Pavkovic, Mira¹ (AUTHOR), Hartmann, Elke¹ (AUTHOR), Siudak, Krystyna¹ (AUTHOR), Freyberger, Alexius¹ (AUTHOR), Hagelschuer, Ina¹ (AUTHOR), Mathar, Ilka¹ (AUTHOR), Hueser, Joerg¹ (AUTHOR), Hahn, Michael G.¹ (AUTHOR), Geiss, Volker¹ (AUTHOR), Eitner, Frank^1,4 (AUTHOR), Sandner, Peter^1,5 (AUTHOR) peter.sandner@bayer.com

Publikováno v: International Journal of Molecular Sciences. Sep2023, Vol. 24 Issue 17, p13226. 20p.

Responses in Blood Pressure and Kidney Function to Soluble Guanylyl Cyclase Stimulation or Activation in Normal and Diabetic Rats

Autor: Rohit Patel, Yiling Fu, Ser Khang, Agnes M. Benardeau, Scott C. Thomson, Volker Vallon

Publikováno v: Nephron. :1-20

Introduction: Agonists of soluble guanylate cyclase (sGC) are being developed as treatment for cardiovascular disease. Most effects of nitric oxide (NO) on glomerular and tubular function are mediated through sGC, but whether sGC agonists mimic these

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::036cbd4444a0fb53ac455ff15bcdfcc0
https://doi.org/10.1159/000526934

Responses in Blood Pressure and Kidney Function to Soluble Guanylyl Cyclase Stimulation or Activation in Normal and Diabetic Rats.

Autor: Patel, Rohit, Fu, Yiling, Khang, Ser, Benardeau, Agnes M., Thomson, Scott C., Vallon, Volker

Publikováno v: Nephron; 2023, Vol. 147 Issue 5, p281-300, 20p

Animal Models of Diabetic Macrovascular Complications: Key Players in the Development of New Therapeutic Approaches

Autor: Suvi E. Heinonen, Guillem Genové, Eva Bengtsson, Thomas Hübschle, Lina Åkesson, Katrin Hiss, Agnes Benardeau, Seppo Ylä-Herttuala, Ann-Cathrine Jönsson-Rylander, Maria F. Gomez

Publikováno v: Journal of Diabetes Research, Vol 2015 (2015)

Diabetes mellitus is a lifelong, incapacitating metabolic disease associated with chronic macrovascular complications (coronary heart disease, stroke, and peripheral vascular disease) and microvascular disorders leading to damage of the kidneys (neph

Externí odkaz: https://doaj.org/article/2f90fe4fbfab4d0fb2fe8675df4da1c4

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