Zobrazeno 1 - 10
of 409
pro vyhledávání: '"A. Bargsten"'
Gene editing of NCF1 loci is associated with homologous recombination and chromosomal rearrangements
Autor:
Federica Raimondi, Kah Mun Siow, Dominik Wrona, Carla Fuster-García, Oleksandr Pastukhov, Michael Schmitz, Katja Bargsten, Lucas Kissling, Daan C. Swarts, Geoffroy Andrieux, Toni Cathomen, Ute Modlich, Martin Jinek, Ulrich Siler, Janine Reichenbach
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-10 (2024)
Abstract CRISPR-based genome editing of pseudogene-associated disorders, such as p47 phox -deficient chronic granulomatous disease (p47 CGD), is challenged by chromosomal rearrangements due to presence of multiple targets. We report that interactions
Externí odkaz:
https://doaj.org/article/93b02712c21d4f31ac658ae71b0f19f4
Autor:
T. Foken, F. X. Meixner, E. Falge, C. Zetzsch, A. Serafimovich, A. Bargsten, T. Behrendt, T. Biermann, C. Breuninger, S. Dix, T. Gerken, M. Hunner, L. Lehmann-Pape, K. Hens, G. Jocher, J. Kesselmeier, J. Lüers, J.-C. Mayer, A. Moravek, D. Plake, M. Riederer, F. Rütz, M. Scheibe, L. Siebicke, M. Sörgel, K. Staudt, I. Trebs, A. Tsokankunku, M. Welling, V. Wolff, Z. Zhu
Publikováno v:
Atmospheric Chemistry and Physics, Vol 12, Iss 4, Pp 1923-1950 (2012)
To investigate the energy, matter and reactive and non-reactive trace gas exchange between the atmosphere and a spruce forest in the German mountain region, two intensive measuring periods were conducted at the FLUXNET site DE-Bay (Waldstein-Weidenbr
Externí odkaz:
https://doaj.org/article/f89890696e3c4b77802fa90713ebd492
Publikováno v:
Biogeosciences, Vol 7, Iss 5, Pp 1425-1441 (2010)
Nitric oxide (NO) plays an important role in the photochemistry of the troposphere. NO from soil contributes up to 40% to the global budget of atmospheric NO. Soil NO emissions are primarily caused by biological activity (nitrification and denitrific
Externí odkaz:
https://doaj.org/article/6fcd4621295246fe8a6b0afa1b0905e7
Publikováno v:
Current Directions in Biomedical Engineering 7 (2021) 21-25
The distinction between malignant and benign tumors is essential to the treatment of cancer. The tissue's elasticity can be used as an indicator for the required tissue characterization. Optical coherence elastography (OCE) probes have been proposed
Externí odkaz:
http://arxiv.org/abs/2109.09362
Autor:
Esser, Julian, Kumar, Shivesh, Peters, Heiner, Bargsten, Vinzenz, Fernandez, Jose de Gea, Mastalli, Carlos, Stasse, Olivier, Kirchner, Frank
Last decades of humanoid research has shown that humanoids developed for high dynamic performance require a stiff structure and optimal distribution of mass--inertial properties. Humanoid robots built with a purely tree type architecture tend to be b
Externí odkaz:
http://arxiv.org/abs/2101.10591
Autor:
Hill, M. P., Humphries, O., Royle, R., Williams, B., Ramsay, M. G., Miscampbell, A., Allan, P., Brown, C. R. D., Hobbs, L. M. R., James, S. F., Hoarty, D. J., Marjoribanks, R. S., Park, J., London, R. A., Tommasini, R., Pukhov, A., Bargsten, C., Hollinger, R., Shlyaptsev, V. N., Capeluto, M. G., Rocca, J. J., Vinko, S. M.
We present picosecond-resolution streaked K-shell spectra from 400 nm-diameter nickel nanowire arrays, demonstrating the ability to generate large volumes of high energy density plasma when combined with the longer pulses typical of the largest short
Externí odkaz:
http://arxiv.org/abs/2007.10410
Akademický článek
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Autor:
Andrea E Prota, Daniel Lucena-Agell, Yuntao Ma, Juan Estevez-Gallego, Shuo Li, Katja Bargsten, Fernando Josa-Prado, Karl-Heinz Altmann, Natacha Gaillard, Shinji Kamimura, Tobias Mühlethaler, Federico Gago, Maria A Oliva, Michel O Steinmetz, Wei-Shuo Fang, J Fernando Díaz
Publikováno v:
eLife, Vol 12 (2023)
Paclitaxel (Taxol) is a taxane and a chemotherapeutic drug that stabilizes microtubules. While the interaction of paclitaxel with microtubules is well described, the lack of high-resolution structural information on a tubulin-taxane complex precludes
Externí odkaz:
https://doaj.org/article/ae0411d1a2f8477a839b678a56356407
Autor:
Raimondi, Federica, Siow, Kah Mun, Wrona, Dominik, Fuster-García, Carla, Pastukhov, Oleksandr, Schmitz, Michael, Bargsten, Katja, Kissling, Lucas, Swarts, Daan C., Andrieux, Geoffroy, Cathomen, Toni, Modlich, Ute, Jinek, Martin, Siler, Ulrich, Reichenbach, Janine
Publikováno v:
Communications Biology; 10/9/2024, Vol. 7 Issue 1, p1-10, 10p
Autor:
Jiang, Yuxiang, Oron, Tal Ronnen, Clark, Wyatt T, Bankapur, Asma R, D'Andrea, Daniel, Lepore, Rosalba, Funk, Christopher S, Kahanda, Indika, Verspoor, Karin M, Ben-Hur, Asa, Koo, Emily, Penfold-Brown, Duncan, Shasha, Dennis, Youngs, Noah, Bonneau, Richard, Lin, Alexandra, Sahraeian, Sayed ME, Martelli, Pier Luigi, Profiti, Giuseppe, Casadio, Rita, Cao, Renzhi, Zhong, Zhaolong, Cheng, Jianlin, Altenhoff, Adrian, Skunca, Nives, Dessimoz, Christophe, Dogan, Tunca, Hakala, Kai, Kaewphan, Suwisa, Mehryary, Farrokh, Salakoski, Tapio, Ginter, Filip, Fang, Hai, Smithers, Ben, Oates, Matt, Gough, Julian, Törönen, Petri, Koskinen, Patrik, Holm, Liisa, Chen, Ching-Tai, Hsu, Wen-Lian, Bryson, Kevin, Cozzetto, Domenico, Minneci, Federico, Jones, David T, Chapman, Samuel, C., Dukka B K., Khan, Ishita K, Kihara, Daisuke, Ofer, Dan, Rappoport, Nadav, Stern, Amos, Cibrian-Uhalte, Elena, Denny, Paul, Foulger, Rebecca E, Hieta, Reija, Legge, Duncan, Lovering, Ruth C, Magrane, Michele, Melidoni, Anna N, Mutowo-Meullenet, Prudence, Pichler, Klemens, Shypitsyna, Aleksandra, Li, Biao, Zakeri, Pooya, ElShal, Sarah, Tranchevent, Léon-Charles, Das, Sayoni, Dawson, Natalie L, Lee, David, Lees, Jonathan G, Sillitoe, Ian, Bhat, Prajwal, Nepusz, Tamás, Romero, Alfonso E, Sasidharan, Rajkumar, Yang, Haixuan, Paccanaro, Alberto, Gillis, Jesse, Sedeño-Cortés, Adriana E, Pavlidis, Paul, Feng, Shou, Cejuela, Juan M, Goldberg, Tatyana, Hamp, Tobias, Richter, Lothar, Salamov, Asaf, Gabaldon, Toni, Marcet-Houben, Marina, Supek, Fran, Gong, Qingtian, Ning, Wei, Zhou, Yuanpeng, Tian, Weidong, Falda, Marco, Fontana, Paolo, Lavezzo, Enrico, Toppo, Stefano, Ferrari, Carlo, Giollo, Manuel, Piovesan, Damiano, Tosatto, Silvio, del Pozo, Angela, Fernández, José M, Maietta, Paolo, Valencia, Alfonso, Tress, Michael L, Benso, Alfredo, Di Carlo, Stefano, Politano, Gianfranco, Savino, Alessandro, Rehman, Hafeez Ur, Re, Matteo, Mesiti, Marco, Valentini, Giorgio, Bargsten, Joachim W, van Dijk, Aalt DJ, Gemovic, Branislava, Glisic, Sanja, Perovic, Vladmir, Veljkovic, Veljko, Veljkovic, Nevena, Almeida-e-Silva, Danillo C, Vencio, Ricardo ZN, Sharan, Malvika, Vogel, Jörg, Kansakar, Lakesh, Zhang, Shanshan, Vucetic, Slobodan, Wang, Zheng, Sternberg, Michael JE, Wass, Mark N, Huntley, Rachael P, Martin, Maria J, O'Donovan, Claire, Robinson, Peter N, Moreau, Yves, Tramontano, Anna, Babbitt, Patricia C, Brenner, Steven E, Linial, Michal, Orengo, Christine A, Rost, Burkhard, Greene, Casey S, Mooney, Sean D, Friedberg, Iddo, Radivojac, Predrag
Background: The increasing volume and variety of genotypic and phenotypic data is a major defining characteristic of modern biomedical sciences. At the same time, the limitations in technology for generating data and the inherently stochastic nature
Externí odkaz:
http://arxiv.org/abs/1601.00891