Zobrazeno 1 - 10
of 314
pro vyhledávání: '"A. Bahinski"'
Autor:
Lindsey Ingleby‐Talecki, Sven C. vanDijkman, Sean P. Oosterholt, Oscar Della Pasqua, Christina Winter, Marianne Cunnington, Linda Rebar, Sergio Forero‐Schwanhaeuser, Vickas Patel, James A. Cooper, Anthony Bahinski, Khuram W. Chaudhary
Publikováno v:
Clinical and Translational Science, Vol 15, Iss 8, Pp 1978-1989 (2022)
Abstract Lamotrigine, approved for use as an antiseizure medication as well as the treatment of bipolar disorder, inhibits sodium channels in the brain to reduce repetitive neuronal firing and pathological release of glutamate. The shared homology of
Externí odkaz:
https://doaj.org/article/ffc94c4b636d4871bfe7eb3ce9458faa
Autor:
Claycomb, William C., Lanson, Nicholas A., Stallworth, Beverly S., Egeland, Daniel B., Delcarpio, Joseph B., Bahinski, Anthony, Izzo, Nicholas J.
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 1998 Mar . 95(6), 2979-2984.
Externí odkaz:
https://www.jstor.org/stable/44783
Akademický článek
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Autor:
Benam, Kambez H., Novak, Richard, Nawroth, Janna, Hirano-Kobayashi, Mariko, Ferrante, Thomas C., Choe, Youngjae, Prantil-Baun, Rachelle, Weaver, James C., Bahinski, Anthony, Parker, Kevin K., Ingber, Donald E.
Publikováno v:
In Cell Systems 23 November 2016 3(5):456-466
Autor:
Remi Villenave, Samantha Q Wales, Tiama Hamkins-Indik, Efstathia Papafragkou, James C Weaver, Thomas C Ferrante, Anthony Bahinski, Christopher A Elkins, Michael Kulka, Donald E Ingber
Publikováno v:
PLoS ONE, Vol 12, Iss 2, p e0169412 (2017)
Analysis of enterovirus infection is difficult in animals because they express different virus receptors than humans, and static cell culture systems do not reproduce the physical complexity of the human intestinal epithelium. Here, using coxsackievi
Externí odkaz:
https://doaj.org/article/81c1e3f16dda46bfb689119331286832
Akademický článek
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K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Nicolas Couvreur, Charles Benson, Jean-Michel Guillon, Yoshiko Okai, Armando Lagrutta, Todd Wisialowski, Michael G. Rolf, Ard Teisman, C. Michael Foley, Hugo M. Vargas, Jean-Pierre Valentin, Maki Ito, Michael J. Engwall, Khuram W. Chaudhary, Gary Gintant, David J. Gallacher, Takashi Yoshinaga, Andrea Greiter-Wilke, Corina Dota, Paul Levesque, Katsuyoshi Chiba, Amy Pointon, Stephen Jenkinson, Anthony Bahinski, Martin Traebert, Brian Guth, Eric Martel, Alan S. Bass, Christa Hegele‐Hartung, William E. Achanzar, Ravikumar Peri, Herbert M. Himmel, Yusheng Qu, Derek J. Leishman
Publikováno v:
Clinical Pharmacology and Therapeutics
Defining an appropriate and efficient assessment of drug‐induced corrected QT interval (QTc) prolongation (a surrogate marker of torsades de pointes arrhythmia) remains a concern of drug developers and regulators worldwide. In use for over 15 years
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::527f989fd8c7a31101405fa082c754d4
https://doi.org/10.1002/cpt.2029
https://doi.org/10.1002/cpt.2029
Autor:
Nurul A N Mohd Yusof, Christine L. Mummery, Leon G.J. Tertoolen, Jessica Nebel, Peter Clements, Eric I. Rossman, Umber Saleem, Ana Krotenberg Garcia, Kate Harris, Maria L. H. Vlaming, Karen McGlynn, Godfrey L. Smith, Xiaoping Xu, Puspita A Katili, Tessa de Korte, Francis L. Burton, Berend J. van Meer, Ingra Mannhardt, Arne Hansen, Chris Denning, Anthony Bahinski, Thomas Eschenhagen
Publikováno v:
Toxicological Sciences
Toxicological Sciences, 176(1), 103-123. OXFORD UNIV PRESS
Toxicological Sciences, 176(1), 103-123. Oxford University Press
Toxicological Sciences, 176(1), 103-123. OXFORD UNIV PRESS
Toxicological Sciences, 176(1), 103-123. Oxford University Press
Animal models are 78% accurate in determining whether drugs will alter contractility of the human heart. To evaluate the suitability of human-induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) for predictive safety pharmacology, we quan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2e9cc5a4d7797253c1110ea6d84aca8
http://europepmc.org/articles/PMC7357169
http://europepmc.org/articles/PMC7357169
Autor:
Haim, Todd E., Wang, Wei, Flagg, Thomas P., Tones, Michael A., Bahinski, Anthony, Numann, Randal E., Nichols, Colin G., Nerbonne, Jeanne M.
Publikováno v:
In Journal of Molecular and Cellular Cardiology 2010 48(2):395-405
Publikováno v:
In Journal of Pharmacological and Toxicological Methods September-October 2021 111