Zobrazeno 1 - 10
of 81
pro vyhledávání: '"A. B. Van Rossum"'
Autor:
Yifu Ding, Daniel J Vanselow, Maksim A Yakovlev, Spencer R Katz, Alex Y Lin, Darin P Clark, Phillip Vargas, Xuying Xin, Jean E Copper, Victor A Canfield, Khai C Ang, Yuxin Wang, Xianghui Xiao, Francesco De Carlo, Damian B van Rossum, Patrick La Riviere, Keith C Cheng
Publikováno v:
eLife, Vol 8 (2019)
Organismal phenotypes frequently involve multiple organ systems. Histology is a powerful way to detect cellular and tissue phenotypes, but is largely descriptive and subjective. To determine how synchrotron-based X-ray micro-tomography (micro-CT) can
Externí odkaz:
https://doaj.org/article/a4fe8abecd5345ed8e6fd5e965f76360
Autor:
Timothy Jegla, Michelle M Nguyen, Chengye Feng, Daniel J Goetschius, Esteban Luna, Damian B van Rossum, Bishoy Kamel, Aditya Pisupati, Elliott S Milner, Melissa M Rolls
Publikováno v:
PLoS Genetics, Vol 12, Iss 12, p e1006457 (2016)
In vertebrate neurons, the axon initial segment (AIS) is specialized for action potential initiation. It is organized by a giant 480 Kd variant of ankyrin G (AnkG) that serves as an anchor for ion channels and is required for a plasma membrane diffus
Externí odkaz:
https://doaj.org/article/7363b8380f3c40e1a46cb9b9312dce9d
Autor:
Sree V Chintapalli, Gaurav Bhardwaj, Reema Patel, Natasha Shah, Randen L Patterson, Damian B van Rossum, Andriy Anishkin, Sean H Adams
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0128496 (2015)
The mechanism(s) by which fatty acids are sequestered and transported in muscle have not been fully elucidated. A potential key player in this process is the protein myoglobin (Mb). Indeed, there is a catalogue of empirical evidence supporting direct
Externí odkaz:
https://doaj.org/article/fde9e7214d0048739c7fb1df5c802087
Autor:
Emma C Baker, Michael J Layden, Damian B van Rossum, Bishoy Kamel, Monica Medina, Eboni Simpson, Timothy Jegla
Publikováno v:
PLoS ONE, Vol 10, Iss 11, p e0142730 (2015)
HCN channels play a unique role in bilaterian physiology as the only hyperpolarization-gated cation channels. Their voltage-gating is regulated by cyclic nucleotides and phosphatidylinositol 4,5-bisphosphate (PIP2). Activation of HCN channels provide
Externí odkaz:
https://doaj.org/article/1c807bd9b1d84b2ca567eca0e1f1a3cd
Autor:
Gabriela Caraveo, Kim A. Caldwell, Jessica Lacoste, Yongbo Zhang, Damian B. van Rossum, Marco Tonelli, Sergei Kuchin, Aishwarya Shevade, Sofia Zaichick, Anthony L. Gaeta, Guy A. Caldwell, Daayun Chung, Mikko Taipale, Jeffrey N. Savas, Shivani Agarwal, Dirk Fasshauer, G. Wiersum, Kaitlyn McGrath, Ludmilla Shuvalova, Wenyu Wen, Mykola Dergai, Andrew K. Shum
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, vol. 118, no. 12, pp. e2016730118
Proceedings of the National Academy of Sciences of the United States of America, vol. 118, no. 12, pp. e2016730118
Significance Ykt6 is a conserved SNARE that plays critical roles along multiple vesicular pathways. To achieve its function, Ykt6 cycles between the cytosol and membrane-bound compartments through reversible lipidation. The mechanism that regulates t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4bd0e23041df6f7c5e6861afa9cb4ac
http://europepmc.org/articles/PMC8000380
http://europepmc.org/articles/PMC8000380
Autor:
Damian B. van Rossum, Alex Y. Lin, Victor A. Canfield, Khai C. Ang, Keith C. Cheng, Georgia K. Thomas
Pleiotropy caused by single-gene mutations is common and poorly understood. A zebrafish null mutant of DNA polymerase α subunit B,huli hutu(hht), evolves a complex pleiotropy associated with DNA damage and S phase arrest across multiple organ system
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::18fbf7fd7b9e117a69025d85a0931f87
https://doi.org/10.1101/2020.12.31.425001
https://doi.org/10.1101/2020.12.31.425001
Autor:
Daayun Chung, Damian B. van Rossum, Gabriela Caraveo, Mykola Dergai, Jeffrey N. Savas, Shivani Agarwal, Sergei Kuchin, Sofia Zaichick, Kaitlyn McGrath, Aishwarya Shevade, Dirk Fasshauer
Membrane fusion, an essential process in all eukaryotes, is driven by SNARE proteins. Ykt6 is an essential SNARE that plays critical roles throughout the secretory, endocytic, and autophagy pathways. Ykt6 activity is thought to be regulated by a conf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5929a0b9be39ebfc934fe12227f2e91e
Autor:
Gaurav Bhardwaj, Kyung Dae Ko, Yoojin Hong, Zhenhai Zhang, Ngai Lam Ho, Sree V Chintapalli, Lindsay A Kline, Matthew Gotlin, David Nicholas Hartranft, Morgen E Patterson, Foram Dave, Evan J Smith, Edward C Holmes, Randen L Patterson, Damian B van Rossum
Publikováno v:
PLoS ONE, Vol 7, Iss 4, p e34261 (2012)
Both multiple sequence alignment and phylogenetic analysis are problematic in the "twilight zone" of sequence similarity (≤ 25% amino acid identity). Herein we explore the accuracy of phylogenetic inference at extreme sequence divergence using a va
Externí odkaz:
https://doaj.org/article/e03936a828f541d5a836cf69de48e3f6
Publikováno v:
PLoS ONE, Vol 5, Iss 10, p e13596 (2010)
A major computational challenge in the genomic era is annotating structure/function to the vast quantities of sequence information that is now available. This problem is illustrated by the fact that most proteins lack comprehensive annotations, even
Externí odkaz:
https://doaj.org/article/3f4f5ae386a54134b4f7b1f1213129b0
Autor:
Nikolas Nikolaidis, Dimitra Chalkia, D Neil Watkins, Roxanne K Barrow, Solomon H Snyder, Damian B van Rossum, Randen L Patterson
Publikováno v:
PLoS ONE, Vol 2, Iss 2, p e204 (2007)
Developmental proteins play a pivotal role in the origin of animal complexity and diversity. We report here the identification of a highly divergent developmental protein superfamily (DANGER), which originated before the emergence of animals (approxi
Externí odkaz:
https://doaj.org/article/3a3459e3ed66445d8c712947caef89cc