Zobrazeno 1 - 10
of 441
pro vyhledávání: '"A. B. Hutchinson"'
Autor:
Meranda M. Masse, Valeria Guzman-Luna, Angela E. Varela, Ummay Mahfuza Shapla, Rachel B. Hutchinson, Aniruddha Srivastava, Wanting Wei, Andrew M. Fuchs, Silvia Cavagnero
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-20 (2024)
Abstract In order to become bioactive, proteins must be translated and protected from aggregation during biosynthesis. The ribosome and molecular chaperones play a key role in this process. Ribosome-bound nascent chains (RNCs) of intrinsically disord
Externí odkaz:
https://doaj.org/article/ccccc773fb76407e9c9ea3cd41c47b41
Autor:
Meranda M. Masse, Rachel B. Hutchinson, Christopher E. Morgan, Heather J. Allaman, Hongqing Guan, Edward W. Yu, Silvia Cavagnero
Publikováno v:
ACS Central Science, Vol 10, Iss 2, Pp 385-401 (2024)
Externí odkaz:
https://doaj.org/article/fe084fcd321b4364800f60a8496315f7
Autor:
Geoffrey B. Hutchinson, Olubukola M. Abiona, Cynthia T. Ziwawo, Anne P. Werner, Daniel Ellis, Yaroslav Tsybovsky, Sarah R. Leist, Charis Palandjian, Ande West, Ethan J. Fritch, Nianshuang Wang, Daniel Wrapp, Seyhan Boyoglu-Barnum, George Ueda, David Baker, Masaru Kanekiyo, Jason S. McLellan, Ralph S. Baric, Neil P. King, Barney S. Graham, Kizzmekia S. Corbett-Helaire
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-11 (2023)
Abstract Multivalent antigen display is a fast-growing area of interest toward broadly protective vaccines. Current nanoparticle-based vaccine candidates demonstrate the ability to confer antibody-mediated immunity against divergent strains of notabl
Externí odkaz:
https://doaj.org/article/977b93340ceb4969a382e3a4758201f2
Autor:
Daniel Ellis, Annie Dosey, Seyhan Boyoglu-Barnum, Young-Jun Park, Rebecca Gillespie, Hubza Syeda, Geoffrey B. Hutchinson, Yaroslav Tsybovsky, Michael Murphy, Deleah Pettie, Nick Matheson, Sidney Chan, George Ueda, Jorge A. Fallas, Lauren Carter, Barney S. Graham, David Veesler, Masaru Kanekiyo, Neil P. King
Publikováno v:
Cell Reports, Vol 42, Iss 12, Pp 113552- (2023)
Summary: Immunogen design approaches aim to control the specificity and quality of antibody responses elicited by next-generation vaccines. Here, we use computational protein design to generate a nanoparticle vaccine platform based on the receptor-bi
Externí odkaz:
https://doaj.org/article/f0b10a69337b4749a61aac233ea0c282
Autor:
Benjamin D. Hallowell, Christina M. Carlson, Jesica R. Jacobs, Mary Pomeroy, Jonathan Steinberg, Mark W. Tenforde, Emily McDonald, Loretta Foster, Leora R. Feldstein, Melissa A. Rolfes, Amber Haynes, Glen R. Abedi, George S. Odongo, Kim Saruwatari, Errin C. Rider, Gina Douville, Neenaben Bhakta, Panagiotis Maniatis, Stephen Lindstrom, Natalie J. Thornburg, Xiaoyan Lu, Brett L. Whitaker, Shifaq Kamili, Senthilkumar K. Sakthivel, Lijuan Wang, Lakshmi Malapati, Janna R. Murray, Brian Lynch, Martin Cetron, Clive Brown, Shahrokh Roohi, Lisa Rotz, Denise Borntrager, Kenta Ishii, Kathleen Moser, Mohammad Rasheed, Brandi Freeman, Sandra Lester, Kizzmekia S. Corbett, Olubukola M. Abiona, Geoffrey B. Hutchinson, Barney S. Graham, Nicki Pesik, Barbara Mahon, Christopher Braden, Casey Barton Behravesh, Rebekah Stewart, Nancy Knight, Aron J. Hall, Marie E. Killerby
Publikováno v:
Emerging Infectious Diseases, Vol 26, Iss 9, Pp 1998-2004 (2020)
To determine prevalence of, seroprevalence of, and potential exposure to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) among a cohort of evacuees returning to the United States from Wuhan, China, in January 2020, we conducted a cross-s
Externí odkaz:
https://doaj.org/article/86cf589d6c4b402bbee4502110a41d1d
Autor:
Seyhan Boyoglu-Barnum, Geoffrey B. Hutchinson, Jeffrey C. Boyington, Syed M. Moin, Rebecca A. Gillespie, Yaroslav Tsybovsky, Tyler Stephens, John R. Vaile, Julia Lederhofer, Kizzmekia S. Corbett, Brian E. Fisher, Hadi M. Yassine, Sarah F. Andrews, Michelle C. Crank, Adrian B. McDermott, John R. Mascola, Barney S. Graham, Masaru Kanekiyo
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Influenza virus hemagglutinin (HA) stem between group 1 and 2 viruses has different glycosylation patterns, likely hampering cross-group protection. Here, Boyoglu-Barnum et al. show that introducing a group 2 glycan into a group 1 stem nanoparticle v
Externí odkaz:
https://doaj.org/article/341c5ca3cd954a0f92613862f3db746e
Publikováno v:
Atmospheric Chemistry and Physics, Vol 20, Pp 2303-2317 (2020)
We investigate techniques for using deep neural networks to produce surrogate models for short-term climate forecasts. A convolutional neural network is trained on 97 years of monthly precipitation output from the 1pctCO2 run (the CO2 concentration i
Externí odkaz:
https://doaj.org/article/a2ef9cbf72df4003b99051735eed1397
Autor:
Elizabeth B. Hutchinson, Anakaren Romero-Lozano, Hannah R. Johnson, Andrew K. Knutsen, Asamoah Bosomtwi, Alexandru Korotcov, Anandakumar Shunmugavel, Sarah G. King, Susan C. Schwerin, Sharon L. Juliano, Bernard J. Dardzinski, Carlo Pierpaoli
Publikováno v:
Frontiers in Neuroscience, Vol 15 (2022)
Pre-clinical models of traumatic brain injury (TBI) have been the primary experimental tool for understanding the potential mechanisms and cellular alterations that follow brain injury, but the human relevance and translational value of these models
Externí odkaz:
https://doaj.org/article/98e6f8c5f3c548deafef3afd4f87b7c7
Autor:
Rebecca J. Loomis, Anthony T. DiPiazza, Samantha Falcone, Tracy J. Ruckwardt, Kaitlyn M. Morabito, Olubukola M. Abiona, Lauren A. Chang, Ria T. Caringal, Vladimir Presnyak, Elisabeth Narayanan, Yaroslav Tsybovsky, Deepika Nair, Geoffrey B. Hutchinson, Guillaume B. E. Stewart-Jones, Lisa A. Kueltzo, Sunny Himansu, John R. Mascola, Andrea Carfi, Barney S. Graham
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Nipah virus (NiV) represents a significant pandemic threat with zoonotic transmission from bats-to-humans with almost annual regional outbreaks characterized by documented human-to-human transmission and high fatality rates. Currently, no vaccine aga
Externí odkaz:
https://doaj.org/article/1645dea2614f43f6baad4345b571338b
Autor:
Rayna M. Addabbo, Rachel B. Hutchinson, Heather J. Allaman, Matthew D. Dalphin, Miranda F. Mecha, Yue Liu, Alexios Staikos, Silvia Cavagnero
Publikováno v:
The Journal of Physical Chemistry B. 127:3990-4014
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a13795cc54f88daf034f3034dc17bcb7
https://doi.org/10.1021/acs.jpcb.2c08485
https://doi.org/10.1021/acs.jpcb.2c08485