Zobrazeno 1 - 10
of 603
pro vyhledávání: '"A. B. Conley"'
Autor:
A. S. Gargis, H. P. McLaughlin, A. B. Conley, C. Lascols, P. A. Michel, J. E. Gee, C. K. Marston, C. B. Kolton, L. M. Rodriguez-R, A. R. Hoffmaster, L. M. Weigel, D. Sue
Publikováno v:
mSystems, Vol 3, Iss 6 (2018)
ABSTRACT Penicillin (PEN) is a low-cost option for anthrax treatment, but naturally occurring resistance has been reported. β-Lactamase expression (bla1, bla2) in Bacillus anthracis is regulated by a sigma factor (SigP) and its cognate anti-sigma fa
Externí odkaz:
https://doaj.org/article/d5d70ec70d9a4083b110c866e3786f6e
Autor:
Christine Lascols, Blake Cherney, Andrew B. Conley, Lavanya Rishishwar, Matthew A. Crawford, Stephen A. Morse, Debra J. Fisher, Kevin Anderson, David R. Hodge, Segaran P. Pillai, Molly A. Hughes, Erum Khan, David Sue
Publikováno v:
Frontiers in Microbiology, Vol 14 (2023)
ObjectivesThe study aim was to investigate multidrug-resistant (MDR) plasmids from a collection of 10 carbapenemase-producing Klebsiella pneumoniae clinical isolates identified within the same healthcare institution in Pakistan. Full characterization
Externí odkaz:
https://doaj.org/article/cabfabeb152f4f138d9091258c547523
Autor:
Kara Keun Lee, Emily T Norris, Lavanya Rishishwar, Andrew B Conley, Leonardo Mariño-Ramírez, John F McDonald, I King Jordan
Publikováno v:
PLOS Global Public Health, Vol 3, Iss 2, p e0001560 (2023)
Despite a substantial overall decrease in mortality, disparities among ethnic minorities in developed countries persist. This study investigated mortality disparities and their associated risk factors for the three largest ethnic groups in the United
Externí odkaz:
https://doaj.org/article/6bce62b8b316442cba64657853187cc4
Publikováno v:
BMC Biology, Vol 18, Iss 1, Pp 1-16 (2020)
Abstract Background Pharmacogenomic (PGx) variants mediate how individuals respond to medication, and response differences among racial/ethnic groups have been attributed to patterns of PGx diversity. We hypothesized that genetic ancestry (GA) would
Externí odkaz:
https://doaj.org/article/59a8dbd987ea4e448fcde1d51466999d
Autor:
Aroon T. Chande, Lavanya Rishishwar, Andrew B. Conley, Augusto Valderrama-Aguirre, Miguel A. Medina-Rivas, I. King Jordan
Publikováno v:
BMC Medical Genetics, Vol 21, Iss S2, Pp 1-14 (2020)
Abstract Background Hispanic/Latino (HL) populations bear a disproportionately high burden of type 2 diabetes (T2D). The ability to predict T2D genetic risk using polygenic risk scores (PRS) offers great promise for improved screening and prevention.
Externí odkaz:
https://doaj.org/article/30c6963538474136b11f0ddce5003804
Autor:
Emily T. Norris, Lavanya Rishishwar, Aroon T. Chande, Andrew B. Conley, Kaixiong Ye, Augusto Valderrama-Aguirre, I. King Jordan
Publikováno v:
Genome Biology, Vol 21, Iss 1, Pp 1-12 (2020)
Abstract Background Admixture occurs when previously isolated populations come together and exchange genetic material. We hypothesize that admixture can enable rapid adaptive evolution in human populations by introducing novel genetic variants (haplo
Externí odkaz:
https://doaj.org/article/9cf38d75626e4421b7b8c052f592b874
Autor:
Heather P. McLaughlin, Julia V. Bugrysheva, Andrew B. Conley, Christopher A. Gulvik, Blake Cherney, Cari B. Kolton, Chung K. Marston, Elke Saile, Erin Swaney, David Lonsway, Amy S. Gargis, Thiphasone Kongphet-Tran, Christine Lascols, Pierre Michel, Julie Villanueva, Alex R. Hoffmaster, Jay E. Gee, David Sue
Publikováno v:
Emerging Infectious Diseases, Vol 26, Iss 2, Pp 358-361 (2020)
Human anthrax cases necessitate rapid response. We completed Bacillus anthracis nanopore whole-genome sequencing in our high-containment laboratory from a human anthrax isolate hours after receipt. The de novo assembled genome showed no evidence of k
Externí odkaz:
https://doaj.org/article/ac2475ca9ed343f6be9c7ddc7aad2b58
Autor:
Meera Ganesh, Craig Cameron Brawley MD, Ashoke Khanwalkar MD, John Mycanka, David B. Conley MD, Robert C. Kern MD, Bruce K. Tan MD, MS
Publikováno v:
OTO Open, Vol 5 (2021)
Objective To evaluate the utility of point-of-care COVID-19 testing for identifying infected patients in an otolaryngology practice. Study Design Retrospective review of 947 patients tested with a point-of-care nucleic acid amplification test for SAR
Externí odkaz:
https://doaj.org/article/1a6413ddf83d4fb893f790faa90ef449
Autor:
Shashwat Deepali Nagar, Andrew B. Conley, Aroon T. Chande, Lavanya Rishishwar, Shivam Sharma, Leonardo Mariño-Ramírez, Gabriela Aguinaga-Romero, Fabricio González-Andrade, I. King Jordan
Publikováno v:
HGG Advances, Vol 2, Iss 4, Pp 100050- (2021)
Summary: We investigated the ancestral origins of four Ecuadorian ethnic groups—Afro-Ecuadorian, Mestizo, Montubio, and the Indigenous Tsáchila—in an effort to gain insight on the relationship between ancestry, culture, and the formation of ethn
Externí odkaz:
https://doaj.org/article/b765fb70cdd04dd6974d3d1053fdca09
Autor:
Shashwat Deepali Nagar, Andrew B. Conley, Shivam Sharma, Lavanya Rishishwar, I. King Jordan, Leonardo Mariño-Ramírez
Publikováno v:
Frontiers in Genetics, Vol 12 (2021)
C-reactive protein (CRP) is a routinely measured blood biomarker for inflammation. Elevated levels of circulating CRP are associated with response to infection, risk for a number of complex common diseases, and psychosocial stress. The objective of t
Externí odkaz:
https://doaj.org/article/49502ef044f94001bfa77f70d2b56f26