Zobrazeno 1 - 10
of 113
pro vyhledávání: '"A. B. Adesida"'
Autor:
A. K. Aissiou, S. Jha, K. Dhunnoo, Z. Ma, D. X. Li, R. Ravin, M. Kunze, K. Wong, A. B. Adesida
Publikováno v:
npj Microgravity, Vol 9, Iss 1, Pp 1-12 (2023)
Abstract Spaceflight and simulated spaceflight microgravity induced osteoarthritic-like alterations at the transcriptomic and proteomic levels in the articular and meniscal cartilages of rodents. But little is known about the effect of spaceflight or
Externí odkaz:
https://doaj.org/article/97153d5c193e4e92a62f16d4a333a754
Autor:
Zhiyao Ma, David Xinzheyang Li, Ryan K. W. Chee, Melanie Kunze, Aillette Mulet-Sierra, Mark Sommerfeldt, Lindsey Westover, Daniel Graf, Adetola B. Adesida
Publikováno v:
Scientific Data, Vol 9, Iss 1, Pp 1-9 (2022)
Abstract Osteoarthritis (OA) primarily affects mechanical load-bearing joints, with the knee being the most common. The prevalence, burden and severity of knee osteoarthritis (KOA) are disproportionately higher in females, but hormonal differences al
Externí odkaz:
https://doaj.org/article/a53b45f6ca7c42a9b0b53f4e2d5f1927
Autor:
Xiaoyi Lan, Yan Liang, Margaret Vyhlidal, Esra JN Erkut, Melanie Kunze, Aillette Mulet-Sierra, Martin Osswald, Khalid Ansari, Hadi Seikaly, Yaman Boluk, Adetola B Adesida
Publikováno v:
Journal of Tissue Engineering, Vol 13 (2022)
The removal of skin cancer lesions on the nose often results in the loss of nasal cartilage. The cartilage loss is either surgically replaced with autologous cartilage or synthetic grafts. However, these replacement options come with donor-site morbi
Externí odkaz:
https://doaj.org/article/94568f7fa85f4f2cb9b1d1ba837138be
Autor:
Zhiyao Ma, David Xinzheyang Li, Melanie Kunze, Aillette Mulet-Sierra, Lindsey Westover, Adetola B. Adesida
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 10 (2022)
Background: Osteoarthritis (OA) primarily affects mechanical load-bearing joints. The knee joint is the most impacted by OA. Knee OA (KOA) occurs in almost all demographic groups, but the prevalence and severity are disproportionately higher in femal
Externí odkaz:
https://doaj.org/article/48b6ebd7ae6640f7bf7d40abe6fc6b07
Autor:
Xiaoyi Lan, Zhiyao Ma, Alexander R. A. Szojka, Melanie Kunze, Aillette Mulet-Sierra, Margaret J. Vyhlidal, Yaman Boluk, Adetola B. Adesida
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 9 (2021)
Objective: The avascular inner regions of the knee menisci cannot self-heal. As a prospective treatment, functional replacements can be generated by cell-based 3D bioprinting with an appropriate cell source and biomaterial. To that end, human meniscu
Externí odkaz:
https://doaj.org/article/c1eb2524b1bd4b0fac780747b86453a6
Autor:
Alexander R. A. Szojka, David Xinzheyang Li, Malou E. J. Sopcak, Zhiyao Ma, Melanie Kunze, Aillette Mulet-Sierra, Samer M. Adeeb, Lindsey Westover, Nadr M. Jomha, Adetola B. Adesida
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 9 (2021)
Meniscus fibrochondrocytes (MFCs) experience simultaneous hypoxia and mechanical loading in the knee joint. Experimental conditions based on these aspects of the native MFC environment may have promising applications in human meniscus tissue engineer
Externí odkaz:
https://doaj.org/article/8dcb5e4b7e43432d9ac2d4b2df2cf4a2
Autor:
Samia Rahman, Alexander R. A. Szojka, Yan Liang, Melanie Kunze, Victoria Goncalves, Aillette Mulet-Sierra, Nadr M. Jomha, Adetola B. Adesida
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
ObjectiveArticular cartilage of the knee joint is avascular, exists under a low oxygen tension microenvironment, and does not self-heal when injured. Human infrapatellar fat pad-sourced mesenchymal stem cells (IFP-MSC) are an arthroscopically accessi
Externí odkaz:
https://doaj.org/article/f0e4a17213264b52b79ff98593272bce
Autor:
Pranidhi Baddam, Daniel Young, Garett Dunsmore, Chunpeng Nie, Farah Eaton, Shokrollah Elahi, Juan Jovel, Adetola B. Adesida, Antoine Dufour, Daniel Graf
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
The nasal septum cartilage is a specialized hyaline cartilage important for normal midfacial growth. Abnormal midfacial growth is associated with midfacial hypoplasia and nasal septum deviation (NSD). However, the underlying genetics and associated f
Externí odkaz:
https://doaj.org/article/45cda7719d7f48a0ad2ccbbdd07c933a
Autor:
Alexander RA Szojka, Rita de Cássia Marqueti, David Xinzheyang Li, Clayton W Molter, Yan Liang, Melanie Kunze, Aillette Mulet-Sierra, Nadr M Jomha, Adetola B Adesida
Publikováno v:
Journal of Tissue Engineering, Vol 12 (2021)
This study investigates the transcriptome response of meniscus fibrochondrocytes (MFCs) to the low oxygen and mechanical loading signals experienced in the knee joint using a model system. We hypothesized that short term exposure to the combined trea
Externí odkaz:
https://doaj.org/article/1872f10f7232417fa7d0fc28f4f8525a
Autor:
Matthew Anderson-Baron, Yan Liang, Melanie Kunze, Aillette Mulet-Sierra, Martin Osswald, Khalid Ansari, Hadi Seikaly, Adetola B. Adesida
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 8 (2021)
ObjectiveHuman nasal septal chondrocytes (NC) are a promising minimally invasive derivable chondrogenic cell source for cartilage repair. However, the quality of NC-derived cartilage is variable between donors. Coculture of NC with mesenchymal stem c
Externí odkaz:
https://doaj.org/article/401bcd0dce4b468bae9bc687874b2d58