Zobrazeno 1 - 10
of 326
pro vyhledávání: '"A. B. Adesida"'
Autor:
Zhiyao Ma, David Xinzheyang Li, Xiaoyi Lan, Adam Bubelenyi, Margaret Vyhlidal, Melanie Kunze, Mark Sommerfeldt, Adetola B. Adesida
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-12 (2024)
Abstract Background Mechanical unloading of the knee articular cartilage results in cartilage matrix atrophy, signifying the osteoarthritic-inductive potential of mechanical unloading. In contrast, mechanical loading stimulates cartilage matrix produ
Externí odkaz:
https://doaj.org/article/a910cd89ada64d5eae23eda1dc460bbe
Autor:
Zhiyao Ma, David Xinzheyang Li, Ryan K. W. Chee, Melanie Kunze, Aillette Mulet-Sierra, Mark Sommerfeldt, Lindsey Westover, Daniel Graf, Adetola B. Adesida
Publikováno v:
Scientific Data, Vol 11, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/62ed8d5e49754c11a64282a5382ece08
Autor:
A. K. Aissiou, S. Jha, K. Dhunnoo, Z. Ma, D. X. Li, R. Ravin, M. Kunze, K. Wong, A. B. Adesida
Publikováno v:
npj Microgravity, Vol 9, Iss 1, Pp 1-12 (2023)
Abstract Spaceflight and simulated spaceflight microgravity induced osteoarthritic-like alterations at the transcriptomic and proteomic levels in the articular and meniscal cartilages of rodents. But little is known about the effect of spaceflight or
Externí odkaz:
https://doaj.org/article/97153d5c193e4e92a62f16d4a333a754
Autor:
Zhiyao Ma, David Xinzheyang Li, Ryan K. W. Chee, Melanie Kunze, Aillette Mulet-Sierra, Mark Sommerfeldt, Lindsey Westover, Daniel Graf, Adetola B. Adesida
Publikováno v:
Scientific Data, Vol 9, Iss 1, Pp 1-9 (2022)
Abstract Osteoarthritis (OA) primarily affects mechanical load-bearing joints, with the knee being the most common. The prevalence, burden and severity of knee osteoarthritis (KOA) are disproportionately higher in females, but hormonal differences al
Externí odkaz:
https://doaj.org/article/a53b45f6ca7c42a9b0b53f4e2d5f1927
Autor:
David Xinzheyang Li, Zhiyao Ma, Alexander RA Szojka, Xiaoyi Lan, Melanie Kunze, Aillette Mulet-Sierra, Lindsey Westover, Adetola B Adesida
Publikováno v:
Journal of Tissue Engineering, Vol 14 (2023)
Cartilage tissue engineering aims to generate functional replacements to treat cartilage defects from damage and osteoarthritis. Human bone marrow-derived mesenchymal stem cells (hBM-MSC) are a promising cell source for making cartilage, but current
Externí odkaz:
https://doaj.org/article/fd58a73541aa4f0d8ac41f4ed82150f9
Autor:
Xiaoyi Lan, Yan Liang, Margaret Vyhlidal, Esra JN Erkut, Melanie Kunze, Aillette Mulet-Sierra, Martin Osswald, Khalid Ansari, Hadi Seikaly, Yaman Boluk, Adetola B Adesida
Publikováno v:
Journal of Tissue Engineering, Vol 13 (2022)
The removal of skin cancer lesions on the nose often results in the loss of nasal cartilage. The cartilage loss is either surgically replaced with autologous cartilage or synthetic grafts. However, these replacement options come with donor-site morbi
Externí odkaz:
https://doaj.org/article/94568f7fa85f4f2cb9b1d1ba837138be
Autor:
Zhiyao Ma, David Xinzheyang Li, Melanie Kunze, Aillette Mulet-Sierra, Lindsey Westover, Adetola B. Adesida
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 10 (2022)
Background: Osteoarthritis (OA) primarily affects mechanical load-bearing joints. The knee joint is the most impacted by OA. Knee OA (KOA) occurs in almost all demographic groups, but the prevalence and severity are disproportionately higher in femal
Externí odkaz:
https://doaj.org/article/48b6ebd7ae6640f7bf7d40abe6fc6b07
Autor:
Xiaoyi Lan, Zhiyao Ma, Alexander R. A. Szojka, Melanie Kunze, Aillette Mulet-Sierra, Margaret J. Vyhlidal, Yaman Boluk, Adetola B. Adesida
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 9 (2021)
Objective: The avascular inner regions of the knee menisci cannot self-heal. As a prospective treatment, functional replacements can be generated by cell-based 3D bioprinting with an appropriate cell source and biomaterial. To that end, human meniscu
Externí odkaz:
https://doaj.org/article/c1eb2524b1bd4b0fac780747b86453a6
Autor:
Alexander R. A. Szojka, David Xinzheyang Li, Malou E. J. Sopcak, Zhiyao Ma, Melanie Kunze, Aillette Mulet-Sierra, Samer M. Adeeb, Lindsey Westover, Nadr M. Jomha, Adetola B. Adesida
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 9 (2021)
Meniscus fibrochondrocytes (MFCs) experience simultaneous hypoxia and mechanical loading in the knee joint. Experimental conditions based on these aspects of the native MFC environment may have promising applications in human meniscus tissue engineer
Externí odkaz:
https://doaj.org/article/8dcb5e4b7e43432d9ac2d4b2df2cf4a2
Autor:
Samia Rahman, Alexander R. A. Szojka, Yan Liang, Melanie Kunze, Victoria Goncalves, Aillette Mulet-Sierra, Nadr M. Jomha, Adetola B. Adesida
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
ObjectiveArticular cartilage of the knee joint is avascular, exists under a low oxygen tension microenvironment, and does not self-heal when injured. Human infrapatellar fat pad-sourced mesenchymal stem cells (IFP-MSC) are an arthroscopically accessi
Externí odkaz:
https://doaj.org/article/f0e4a17213264b52b79ff98593272bce