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Akademický článek

Radiation-induced morphea of the breast – characterization and treatment of fibroblast dysfunction with repurposed mesalazine

Autor: Stephan R. Künzel, Erik Klapproth, Nick Zimmermann, Susanne Kämmerer, Mario Schubert, Karolina Künzel, Maximilian Hoffmann, Stephan Drukewitz, Anne Vehlow, Jiri Eitler, Marieke Arriens, Jessica Thiel, Romy Kronstein-Wiedemann, Maximiliane Tietze, Stefan Beissert, Bertold Renner, Ali El-Armouche, Claudia Günther

Publikováno v: Scientific Reports, Vol 14, Iss 1, Pp 1-17 (2024)

Abstract Radiation-induced morphea (RIM) is a rare complication of radiotherapy presenting as inflammatory fibrosis, most commonly reported in breast cancer patients. As underlying disease mechanisms are not well understood, targeted therapies are la

Externí odkaz: https://doaj.org/article/ca14d9c2e1744a85acf698b849bb68f5

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Akademický článek

Neutrophils isolated from systemic lupus erythematosus patients exhibit a distinct functional phenotype

Autor: Neelakshi R. Jog, Catriona A. Wagner, Teresa Aberle, Eliza F. Chakravarty, Cristina Arriens, Joel M. Guthridge, Judith A. James

Publikováno v: Frontiers in Immunology, Vol 15 (2024)

Neutrophil dysregulation, particularly of a low-density subset, is associated with systemic lupus erythematosus (SLE); however, the exact role of normal-density neutrophils in SLE remains unknown. This study compares activation and functional phenoty

Externí odkaz: https://doaj.org/article/39ecd1bed286419da5fbcca3181ab3fc

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Akademický článek

Protocol for virtual physical examination in an observational, longitudinal study evaluating virtual outcome measures in SLE

Autor: Cynthia Aranow, Maria Dall'Era, Meggan Mackay, Diane L Kamen, Wei Tang, Mimi Y Kim, Cristina Arriens, Anca D Askanase, Leila Khalili, Julia Barasch

Publikováno v: Lupus Science and Medicine, Vol 10, Iss 2 (2023)

Objective There is a lack of data on the use of telemedicine (TM) in SLE. SLE outcome measures remain complex, and clinicians and clinical trialists have raised concerns about the accuracy of virtual disease activity measures. This study evaluates th

Externí odkaz: https://doaj.org/article/c2f0777d2f184261811fc1b174d00200

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Akademický článek

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Akademický článek

Ancestry-based differences in the immune phenotype are associated with lupus activity

Publikováno v: JCI Insight, Vol 8, Iss 16 (2023)

Systemic lupus erythematosus (SLE) affects 1 in 537 Black women, which is >2-fold more than White women. Black patients develop the disease at a younger age, have more severe symptoms, and have a greater chance of early mortality. We used a multiomic

Externí odkaz: https://doaj.org/article/e17965113ade415ab50fbba3c6fd56ef

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Akademický článek

Phenological mismatch is less important than total nectar availability for checkerspot butterflies.

Autor: Crone, Elizabeth E.¹ (AUTHOR) ecrone@ucdavis.edu, Arriens, June V.¹ (AUTHOR), Brown, Leone M.¹ (AUTHOR)

Publikováno v: Ecology. Nov2024, p1. 17p. 5 Illustrations.

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