Zobrazeno 1 - 10
of 85
pro vyhledávání: '"A. Arockia Jeyaprakash"'
Autor:
Natalia Y. Kochanova, Petra Vizjak, Maria Alba Abad, William C. Earnshaw, A. Arockia Jeyaprakash, Georg Kustatscher
Publikováno v:
Wellcome Open Research, Vol 8 (2024)
Background Unicorn™ software on Äkta liquid chromatography instruments outputs chromatography profiles of purified biological macromolecules. While the plots generated by the instrument software are very helpful to inspect basic chromatogram prope
Externí odkaz:
https://doaj.org/article/ee935080b91b48e3bb133dcad9ca0ad1
Autor:
Natalia Y. Kochanova, Petra Vizjak, Maria Alba Abad, William C. Earnshaw, A. Arockia Jeyaprakash, Georg Kustatscher
Publikováno v:
Wellcome Open Research, Vol 8 (2023)
Background: UnicornTM software on Äkta liquid chromatography instruments outputs chromatography profiles of purified biological macromolecules. While the plots generated by the instrument software are very helpful to inspect basic chromatogram prope
Externí odkaz:
https://doaj.org/article/e04a79c7246140bdb577940e882246dc
Autor:
Andrea Rizzotto, Sylvain Tollis, Nhan T. Pham, Yijing Zheng, Maria Alba Abad, Jan Wildenhain, A. Arockia Jeyaprakash, Manfred Auer, Mike Tyers, Eric C. Schirmer
Publikováno v:
Cells, Vol 13, Iss 1, p 57 (2023)
Increased nuclear size correlates with lower survival rates and higher grades for prostate cancer. The short-chain dehydrogenase/reductase (SDR) family member DHRS7 was suggested as a biomarker for use in prostate cancer grading because it is largely
Externí odkaz:
https://doaj.org/article/ac36edf31ab54a338b9f8da30a7b02e4
Autor:
Cinthia Aguilera, Stefan Hümmer, Marc Masanas, Elisabeth Gabau, Miriam Guitart, A. Arockia Jeyaprakash, Miguel F. Segura, Anna Santamaria, Anna Ruiz
Publikováno v:
Frontiers in Neuroscience, Vol 15 (2021)
KIF1A is a microtubule-dependent motor protein responsible for fast anterograde transport of synaptic vesicle precursors in neurons. Pathogenic variants in KIF1A have been associated with a wide spectrum of neurological disorders. Here, we report a p
Externí odkaz:
https://doaj.org/article/a076fd12eddd46a3a646d90898b8af95
Autor:
Oscar Molina, Giulia Vargiu, Maria Alba Abad, Alisa Zhiteneva, A. Arockia Jeyaprakash, Hiroshi Masumoto, Natalay Kouprina, Vladimir Larionov, William C. Earnshaw
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-16 (2016)
Centromeres are centrochromatin domains with CENP-A and H3 nucleosomes carrying transcription-associated modifications. Here the authors target synthetic modules to the centromeres to show that transcription plus histone modifications are required fo
Externí odkaz:
https://doaj.org/article/7355b73cb5fc45f4a8cb124130f7a9aa
Autor:
Virginie Roure, Bethan Medina-Pritchard, Vasiliki Lazou, Luciano Rago, Eduard Anselm, Daniela Venegas, A. Arockia Jeyaprakash, Patrick Heun
Publikováno v:
Cell Reports, Vol 29, Iss 2, Pp 464-479.e5 (2019)
Summary: The centromere is an essential chromosomal region required for accurate chromosome segregation. Most eukaryotic centromeres are defined epigenetically by the histone H3 variant, centromere protein (CENP)-A, yet how its self-propagation is ac
Externí odkaz:
https://doaj.org/article/ebbc10f9431342a7a99291e7ca91baec
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 6 (2018)
Protein kinases are major regulators of mitosis, with over 30% of the mitotic proteome phosphorylated on serines, threonines and tyrosines. The human genome encodes for 518 kinases that have a structurally conserved catalytic domain and includes abou
Externí odkaz:
https://doaj.org/article/9d2336d823114ff0aed99f419f88cbb6
Autor:
Luisa Capalbo, Ioanna Mela, Maria Alba Abad, A. Arockia Jeyaprakash, J. Michael Edwardson, Pier Paolo D'Avino
Publikováno v:
Open Biology, Vol 6, Iss 10 (2016)
The chromosomal passenger complex (CPC)—composed of Aurora B kinase, Borealin, Survivin and INCENP—surveys the fidelity of genome segregation throughout cell division. The CPC has been proposed to prevent polyploidy by controlling the final separ
Externí odkaz:
https://doaj.org/article/b7fce02097a447bfb0029e65ece34214
Autor:
Koly Aktar, Thomas Davies, Ioanna Leontiou, Ivan Clark, Christos Spanos, Edward Wallace, Laura Tuck, A. Arockia Jeyaprakash, Kevin G. Hardwick
Cryptococcus neoformansis an opportunistic, human fungal pathogen which undergoes fascinating switches in cell cycle control and ploidy when it encounters stressful environments such as the human lung. Here we carry out a mechanistic analysis of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e6c720665a14ca92d6084ffe90f6a02d
https://doi.org/10.1101/2023.04.09.536157
https://doi.org/10.1101/2023.04.09.536157
Autor:
Marco Novais-Cruz, Maria Alba Abad, Wilfred FJ van IJcken, Niels Galjart, A Arockia Jeyaprakash, Helder Maiato, Cristina Ferrás
Publikováno v:
eLife, Vol 7 (2018)
Recent studies have challenged the prevailing dogma that transcription is repressed during mitosis. Transcription was also proposed to sustain a robust spindle assembly checkpoint (SAC) response. Here, we used live-cell imaging of human cells, RNA-se
Externí odkaz:
https://doaj.org/article/c3856abb5ad74415bb65bc3b4e3502e2