Zobrazeno 1 - 10
of 162
pro vyhledávání: '"A. Arnal-Estapé"'
Autor:
Sally J. Adua, Anna Arnal-Estapé, Minghui Zhao, Bowen Qi, Zongzhi Z. Liu, Carolyn Kravitz, Heather Hulme, Nicole Strittmatter, Francesc López-Giráldez, Sampada Chande, Alexandra E. Albert, Mary-Ann Melnick, Bomiao Hu, Katerina Politi, Veronica Chiang, Nicola Colclough, Richard J. A. Goodwin, Darren Cross, Paul Smith, Don X. Nguyen
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
While EGFR-targeted therapies have clinical benefit, drug-resistant brain metastases present a major obstacle. Here, the authors identify a genetic signature in brain metastatic lesions associated with osimertinib resistance and find RhoA to have an
Externí odkaz:
https://doaj.org/article/3190ed6c2b6648c6bd0e559653995e8f
Akademický článek
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Autor:
Wesley L. Cai, Celeste B. Greer, Jocelyn F. Chen, Anna Arnal-Estapé, Jian Cao, Qin Yan, Don X. Nguyen
Publikováno v:
BMC Medical Genomics, Vol 13, Iss 1, Pp 1-18 (2020)
Abstract Background Few somatic mutations have been linked to breast cancer metastasis, whereas transcriptomic differences among primary tumors correlate with incidence of metastasis, especially to the lungs and brain. However, the epigenomic alterat
Externí odkaz:
https://doaj.org/article/ab87df052f1042da9558ebcc14ccc2e6
Autor:
Wingrove, Emily, Liu, Zongzhi Z., Patel, Kiran D., Arnal-Estapé, Anna, Cai, Wesley L., Melnick, Mary-Ann, Politi, Katerina, Monteiro, Cátia, Zhu, Lucía, Valiente, Manuel, Kluger, Harriet M., Chiang, Veronica L., Nguyen, Don X.
Publikováno v:
In Cell Reports 23 April 2019 27(4):1277-1292
Autor:
Maher Hanoun, Anna Arnal-Estapé, Maria Maryanovich, Ali H. Zahalka, Sarah K. Bergren, Chee W. Chua, Avigdor Leftin, Patrik N. Brodin, Michael M. Shen, Chandan Guha, Paul S. Frenette
Publikováno v:
Stem Cell Reports, Vol 12, Iss 6, Pp 1201-1211 (2019)
Summary: In the prostate, stem and progenitor cell regenerative capacities have been ascribed to both basal and luminal epithelial cells. Here, we show that a rare subset of mesenchymal cells in the prostate are epithelial-primed Nestin-expressing ce
Externí odkaz:
https://doaj.org/article/15df5a89ccbf40da95f5ba68658f136d
Publikováno v:
Cold Spring Harbor perspectives in medicine. 11(12)
Experimental preclinical models have been a cornerstone of lung cancer translational research. Work in these model systems has provided insights into the biology of lung cancer subtypes and their origins, contributed to our understanding of the mecha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b09c9c17ef606b4da5ad5816a49a244
https://pubmed.ncbi.nlm.nih.gov/34518338
https://pubmed.ncbi.nlm.nih.gov/34518338
Autor:
Zahalka, Ali H., Arnal-Estapé, Anna, Maryanovich, Maria, Nakahara, Fumio, Cruz, Cristian D., Finley, Lydia W. S., Frenette, Paul S.
Publikováno v:
Science, 2017 Oct . 358(6361), 321-326.
Externí odkaz:
https://www.jstor.org/stable/26400556
Akademický článek
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Autor:
Don X. Nguyen, Malaiyalam Mariappan, Paul D. Cao, Minghui Zhao, Zongzhi Liu, Gary W. Cline, Anna Arnal-Estapé, Wesley L. Cai, Sally J. Adua, Alexandra E. Albert
This figure shows that ASNS mediates protein translation during amino acid deprivation.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15356a23ce1ab1d69525e1eb42f4a183
https://doi.org/10.1158/1541-7786.22513200.v1
https://doi.org/10.1158/1541-7786.22513200.v1
Autor:
Don X. Nguyen, Malaiyalam Mariappan, Paul D. Cao, Minghui Zhao, Zongzhi Liu, Gary W. Cline, Anna Arnal-Estapé, Wesley L. Cai, Sally J. Adua, Alexandra E. Albert
Supplementary Table 2 shows differential gene expression in LUAD cells treated with ISRIB during asparagine deprivation.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cd874e05f1d07c112067fa22289a4fa
https://doi.org/10.1158/1541-7786.22513179
https://doi.org/10.1158/1541-7786.22513179