Zobrazeno 1 - 3
of 3
pro vyhledávání: '"A. Andrew Aprikyan"'
Autor:
David C. Dale, Vahagn Makaryan, Audrey Anna Bolyard, Merideth L. Kelley, Breanna Fletcher, A. Andrew Aprikyan
Publikováno v:
Journal of Leukocyte Biology. 102:1143-1151
Mutations in ELANE, the gene for neutrophil elastase (NE), a protease expressed early in neutrophil development, are the most frequent cause of cyclic (CyN) and severe congenital neutropenia (SCN). We hypothesized that inhibitors of NE, acting either
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7a29fe4e0b08754c0ab1819494ca3e0
https://doi.org/10.1189/jlb.5a1016-445r
https://doi.org/10.1189/jlb.5a1016-445r
Autor:
Vahagn Makaryan, Yigal Dror, Willem Kulik, David C. Dale, Andranik Andrew Aprikyan, Frédéric M. Vaz, Christopher Allen
Publikováno v:
European Journal of Haematology. 88:195-209
Barth syndrome (BTHS), a rare, X-linked, recessive disease, is characterized by neutropenia and cardiomyopathy. BTHS is caused by loss-of-function mutations of the tafazzin (TAZ) gene. We developed a model of BTHS by transfecting human HL60 myeloid p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::13af68b7ff20cd165532bd32552d0a81
https://doi.org/10.1111/j.1600-0609.2011.01725.x
https://doi.org/10.1111/j.1600-0609.2011.01725.x
Publikováno v:
Seminars in Hematology. 39:89-94
Cyclic neutropenia is a rare hematologic disorder, characterized by repetitive episodes of fever, mouth ulcers, and infections attributable to recurrent severe neutropenia. Fluctuations in blood cells are due to oscillatory production of cells by the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::efa40b8d4f4dc7897fcb9e70e38ebc19
https://doi.org/10.1053/shem.2002.31917
https://doi.org/10.1053/shem.2002.31917