Zobrazeno 1 - 10
of 28
pro vyhledávání: '"A. Alexandru Naum"'
Autor:
Alexandru Naum, Mikko J. Järvisalo, Marco Bucci, Kjell Någren, Pirjo Nuutila, Piero A. Salvadori, Ronald Borra, Patricia Iozzo, Juhani Knuuti, Timo Savunen, Barbara A. Fielding, Anne Roivainen, Jan Kiss, Kirsi A. Virtanen, Ele Ferrannini, Letizia Guiducci
Publikováno v:
Gastroenterology, 139(3), 846-856. W B SAUNDERS CO-ELSEVIER INC
BACKGROUND & AIMS: Hepatic lipotoxicity results from and contributes to obesity-related disorders. It is a challenge to study human metabolism of fatty acids (FAs) in the liver. We combined (11)C-palmitate imaging by positron emission tomography (PET
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::caea40fbbafe5edd79c5c68e2df071cc
https://ora.ox.ac.uk/objects/uuid:b553708d-99e7-4c4a-8796-4db6ddf79b3d
https://ora.ox.ac.uk/objects/uuid:b553708d-99e7-4c4a-8796-4db6ddf79b3d
Autor:
Sami Länkimäki, Tove J. Grönroos, Merja Haaparanta, Olli Eskola, Juhani Knuuti, Sarita Forsback, Päivi Marjamäki, Jan Kiss, Olof Solin, Alexandru Naum, Jörgen Bergman, Timo Savunen
Publikováno v:
European Journal of Nuclear Medicine and Molecular Imaging. 39:800-810
Purpose 6-[18F]Fluorodopamine (4-(2-aminoethyl)-5-[18F]fluorobenzene-1,2-diol, 6-[18F]FDA) is a tracer for imaging sympathetically innervated tissues. Previous electrophilic labelling methods produced 6-[18F]FDA with low specific radioactivity (SA) w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fd3b492787cd0ced7520b6d92b2fb465
https://doi.org/10.1007/s00259-011-2032-5
https://doi.org/10.1007/s00259-011-2032-5
Autor:
Alexandru Naum, Jeroen J. Bax, Juhani Knuuti, Heikki Ukkonen, Antti Saraste, Juhani Koistinen, Laurens F. Tops
Publikováno v:
European Journal of Nuclear Medicine and Molecular Imaging. 36:2042-2048
Right ventricular (RV) apical pacing induces dyssynchrony by a left bundle branch block type electrical activation sequence in the heart and may impair left ventricular (LV) function. Whether these functional changes are accompanied by changes in myo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca54651e2be275451d201d0f9ee185aa
https://doi.org/10.1007/s00259-009-1200-3
https://doi.org/10.1007/s00259-009-1200-3
Autor:
Kjell Någren, Lionel H. Opie, Birger Hesse, Erik Engblom, K.E. Juhani Airaksinen, Patricia Iozzo, Alexandru Naum, Mika Scheinin, Juhani Knuuti, Helena Tuunanen, Heikki Ukkonen, Pirjo Nuutila
Publikováno v:
Circulation. 118:1250-1258
Background— The anti-ischemic agent trimetazidine improves ejection fraction in heart failure that is hypothetically linked to inhibitory effects on cardiac free fatty acid (FFA) oxidation. However, FFA oxidation remains unmeasured in humans. We in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55b5c57c107461998cd7e9bfcb0662d1
https://doi.org/10.1161/circulationaha.108.778019
https://doi.org/10.1161/circulationaha.108.778019
Autor:
Alexandru Naum, Juhani Knuuti, Ronald Borra, Patricia Iozzo, Sara Rigazio, Mikko Kankaanpää, Kjell Någren, Helena Tuunanen, Pirjo Nuutila, Hanna-Riikka Lehto, Riitta Parkkola, Claudia Simi
Publikováno v:
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM, 295(2), E413-E419. AMER PHYSIOLOGICAL SOC
Lipolysis may regulate liver free fatty acid (FFA) uptake and triglyceride accumulation; both are potential causes of insulin resistance and liver damage. We evaluated whether 1) systemic FFA release is the major determinant of liver FFA uptake in fa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d1ef0e85759534cae4516171ad171c5
https://doi.org/10.1152/ajpendo.00744.2007
https://doi.org/10.1152/ajpendo.00744.2007
Autor:
Pirjo Nuutila, Juhani Knuuti, Lionel H. Opie, Birger Hesse, Erik Engblom, K.E. Juhani Airaksinen, Alexandru Naum, Heikki Ukkonen, Patricia Iozzo, Kjell Någren, Helena Tuunanen
Publikováno v:
Circulation. 114:2130-2137
Background— Metabolic modulators that enhance myocardial glucose metabolism by inhibiting free fatty acid (FFA) metabolism may improve cardiac function in heart failure patients. We studied the effect of acute FFA withdrawal on cardiac function in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7e5657f6729634241c3195d4e305fae
https://doi.org/10.1161/circulationaha.106.645184
https://doi.org/10.1161/circulationaha.106.645184
Autor:
Mikko J. Järvisalo, Vesa Oikonen, Pirjo Nuutila, Marko S. Laaksonen, Mika Teräs, Helena Tuunanen, Alexandru Naum, Juhani Knuuti, Jukka Kemppainen
Publikováno v:
European Journal of Nuclear Medicine and Molecular Imaging. 32:1378-1383
Patient motion during dynamic PET studies is a well-documented source of errors. The purpose of this study was to investigate the incidence of frame-to-frame motion in dynamic ( 15)O-water myocardial perfusion PET studies, to test the efficacy of mot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9534f299c934780d5b5f729197faf57c
https://doi.org/10.1007/s00259-005-1846-4
https://doi.org/10.1007/s00259-005-1846-4
Autor:
Matti Luotolahti, Juhani Knuuti, Pirjo Nuutila, Tapani Rönnemaa, Alexandru Naum, Jan Sundell, H Laine, Tuula Janatuinen, Olli T. Raitakari
Publikováno v:
Diabetic Medicine. 22:45-51
Aims Subjects with Type 1 diabetes have impaired coronary vasoreactivity but the independent role of glycaemic control on myocardial perfusion is less clear. We examined the effect of lifetime glycaemic exposure on coronary vasoreactivity in 43 other
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad4aa8e2074137d835ed3d6725c70654
https://doi.org/10.1111/j.1464-5491.2005.01356.x
https://doi.org/10.1111/j.1464-5491.2005.01356.x
Autor:
Jeroen J. Bax, K.E. Juhani Airaksinen, Juhani Knuuti, Juhani Koistinen, Riikka Kalliokoski, Antti Ylitalo, Kira Q. Stolen, Stephan G. Nekolla, Alexandru Naum, Jan Sundell, Erik Engblom
Publikováno v:
Journal of the American College of Cardiology. 43:1027-1033
ObjectivesThe effects of long-term cardiac resynchronization therapy (CRT) on left ventricular (LV) energetics and metabolic reserve were evaluated.BackgroundCardiac resynchronization therapy is a new therapy for patients with drug-refractory severe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ee2af3f439608b984019eeaa36abc6c
https://doi.org/10.1016/j.jacc.2003.10.044
https://doi.org/10.1016/j.jacc.2003.10.044
Publikováno v:
Acta Radiologica Short Reports
Acta Radiologica Open, Vol 1, Iss 8, Pp 1-3 (2012)
Acta Radiologica Open, Vol 1, Iss 8, Pp 1-3 (2012)
Background The standardized uptake value (SUV) is the most common estimate of metabolic activity used in clinical positron emission tomography (PET). Several biological and technological factors influence the accurate SUV calculation. Purpose To asse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d37fa557e52f26aa674663e56a4aa09a
https://doi.org/10.1258/arsr.2012.120038
https://doi.org/10.1258/arsr.2012.120038