Zobrazeno 1 - 10
of 104
pro vyhledávání: '"A. Aartse"'
Autor:
E. I. M. M. Reiss, M. M. van Haaren, J. van Schooten, M. A. F. Claireaux, P. Maisonnasse, A. Antanasijevic, J. D. Allen, I. Bontjer, J. L. Torres, W-H Lee, G. Ozorowski, N. Vázquez Bernat, M. Kaduk, Y. Aldon, J. A. Burger, H. Chawla, A. Aartse, M. Tolazzi, H. Gao, P. Mundsperger, M. Crispin, D. C. Montefiori, G. B. Karlsson Hedestam, G. Scarlatti, A. B. Ward, R. Le Grand, R. Shattock, N. Dereuddre-Bosquet, R. W. Sanders, M. J. van Gils
Publikováno v:
npj Vaccines, Vol 7, Iss 1, Pp 1-13 (2022)
Abstract The HIV-1 envelope glycoprotein (Env) trimer is the key target for vaccines aimed at inducing neutralizing antibodies (NAbs) against HIV-1. The clinical candidate immunogen ConM SOSIP.v7 is a stabilized native-like HIV-1 Env trimer based on
Externí odkaz:
https://doaj.org/article/d919d26129cb4d55a6a5afbc08a9a26e
Autor:
Iván del Moral-Sánchez, Edmund G. Wee, Yuejiao Xian, Wen-Hsin Lee, Joel D. Allen, Alba Torrents de la Peña, Rebeca Fróes Rocha, James Ferguson, André N. León, Sylvie Koekkoek, Edith E. Schermer, Judith A. Burger, Sanjeev Kumar, Robby Zwolsman, Mitch Brinkkemper, Aafke Aartse, Dirk Eggink, Julianna Han, Meng Yuan, Max Crispin, Gabriel Ozorowski, Andrew B. Ward, Ian A. Wilson, Tomáš Hanke, Kwinten Sliepen, Rogier W. Sanders
Publikováno v:
npj Vaccines, Vol 9, Iss 1, Pp 1-18 (2024)
Abstract Recombinant native-like HIV-1 envelope glycoprotein (Env) trimers are used in candidate vaccines aimed at inducing broadly neutralizing antibodies. While state-of-the-art SOSIP or single-chain Env designs can be expressed as native-like trim
Externí odkaz:
https://doaj.org/article/9406da7e97304295838f177acd6e13b0
Autor:
Petra Mooij, Daniella Mortier, Aafke Aartse, Alexandre B. Murad, Ricardo Correia, António Roldão, Paula M. Alves, Zahra Fagrouch, Dirk Eggink, Norbert Stockhofe, Othmar G. Engelhardt, Ernst J. Verschoor, Marit J. van Gils, Willy M. Bogers, Manuel J. T. Carrondo, Edmond J. Remarque, Gerrit Koopman
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
The first exposure to influenza is presumed to shape the B-cell antibody repertoire, leading to preferential enhancement of the initially formed responses during subsequent exposure to viral variants. Here, we investigated whether this principle rema
Externí odkaz:
https://doaj.org/article/fe0da1bcfd6c40f6beed32ab73a26fdd
Akademický článek
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Autor:
Marloes Grobben, Hannah G. Juncker, Karlijn van der Straten, A. H. Ayesha Lavell, Michiel Schinkel, David T. P. Buis, Maarten F. Wilbrink, Khadija Tejjani, Mathieu A. F. Claireaux, Aafke Aartse, Christianne J. M. de Groot, Dasja Pajkrt, Marije K. Bomers, Jonne J. Sikkens, Marit J. van Gils, Johannes B. van Goudoever, Britt J. van Keulen
Publikováno v:
Microbiology Spectrum, Vol 10, Iss 4 (2022)
ABSTRACT Infants may develop severe viral respiratory tract infections because their immune system is still developing in the first months after birth. Human milk provides passive humoral immunity during the first months of life. During the COVID-19
Externí odkaz:
https://doaj.org/article/909569c5a9de4c9f987a368a0d96bc0e
Akademický článek
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Autor:
Aafke Aartse, Dirk Eggink, Mathieu Claireaux, Sarah van Leeuwen, Petra Mooij, Willy M. Bogers, Rogier W. Sanders, Gerrit Koopman, Marit J. van Gils
Publikováno v:
Vaccines, Vol 9, Iss 7, p 717 (2021)
Antibody responses against the influenza A virus hemagglutinin (HA)-protein are studied intensively because they can protect against (re)infection. Previous studies have focused on antibodies targeting the head or stem domains, while other possible s
Externí odkaz:
https://doaj.org/article/d7481aee16c94446af19c78274fa4907
Autor:
Mathieu Claireaux, Tom G. Caniels, Marlon de Gast, Julianna Han, Denise Guerra, Gius Kerster, Barbera D. C. van Schaik, Aldo Jongejan, Angela I. Schriek, Marloes Grobben, Philip J. M. Brouwer, Karlijn van der Straten, Yoann Aldon, Joan Capella-Pujol, Jonne L. Snitselaar, Wouter Olijhoek, Aafke Aartse, Mitch Brinkkemper, Ilja Bontjer, Judith A. Burger, Meliawati Poniman, Tom P. L. Bijl, Jonathan L. Torres, Jeffrey Copps, Isabel Cuella Martin, Steven W. de Taeye, Godelieve J. de Bree, Andrew B. Ward, Kwinten Sliepen, Antoine H. C. van Kampen, Perry D. Moerland, Rogier W. Sanders, Marit J. van Gils
Publikováno v:
Nature communications, 13(1):4539. Nature Publishing Group
Delineating the origins and properties of antibodies elicited by SARS-CoV-2 infection and vaccination is critical for understanding their benefits and potential shortcomings. Therefore, we investigate the SARS-CoV-2 spike (S)-reactive B cell repertoi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2eb4a9d4da7b0060c19cdda4b2f4305a
https://pure.amc.nl/en/publications/a-public-antibody-class-recognizes-an-s2-epitope-exposed-on-open-conformations-of-sarscov2-spike(18966f61-4342-4b87-96d4-a1f2c2baf771).html
https://pure.amc.nl/en/publications/a-public-antibody-class-recognizes-an-s2-epitope-exposed-on-open-conformations-of-sarscov2-spike(18966f61-4342-4b87-96d4-a1f2c2baf771).html
Autor:
Aafke Aartse, Daniella Mortier, Petra Mooij, Sam Hofman, Marlies M. van Haaren, Martin Corcoran, Gunilla B. Karlsson Hedestam, Dirk Eggink, Mathieu Claireaux, Willy M. J. M. Bogers, Marit J. van Gils, Gerrit Koopman
Publikováno v:
Frontiers in immunology, 13:1026951. Frontiers Media S.A.
Several studies have shown that the first encounter with influenza virus shapes the immune response to future infections or vaccinations. However, a detailed analysis of the primary antibody response is lacking as this is difficult to study in humans
Akademický článek
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