Zobrazeno 1 - 10
of 47
pro vyhledávání: '"A. A. V. Tortorella"'
Publikováno v:
European Psychiatry, Vol 66, Pp S1046-S1046 (2023)
Introduction The use of diagnostic categories, although useful, fails in capturing the psychopathological complexity of the individual case. As for schizophrenia spectrum disorders, positive symptoms are not always included in the presentation, so fu
Externí odkaz:
https://doaj.org/article/0b4887e8ba7346e18d04ee421e1aef8f
Autor:
G. Cappannini, S. Bianchi, G. Menculini, B. Semeraro, F. De Giorgi, K. Amantini, P. Moretti, A. A. V. Tortorella
Publikováno v:
European Psychiatry, Vol 66, Pp S197-S197 (2023)
Introduction Circadian rhythms, defined as endogenous oscillations that regulate metabolism, physiology and behaviour, may be frequently disrupted in mood disorders, influencing their clinical presentation and course (Srinivasan V. et al. World J Bio
Externí odkaz:
https://doaj.org/article/d52ddd1730334c4a82e97286b8c95a46
Autor:
M, Pezzi, E, Le Piane, A M, Giglio, L, Pagnotta, A, Scozzafava, V, Tortorella, A, Sergi, M, Verre
Publikováno v:
La Clinica terapeutica. 166(2)
Posterior Reversible Encephalopathy Syndrome (PRES) is a neurological complication associated with several medical conditions and it has been described in clinical findings of seizures, headache, vomiting, altered mental status, and visual changes an
Publikováno v:
Journal of Medicinal Chemistry. 41:3940-3947
Several 3, 3-dimethyl-N-[omega-(tetrahydronaphthalen-1-yl)alkyl]piperidine derivatives and some related compounds were prepared. Their affinities and sigma-subtype selectivities were investigated by radioligand binding assays, labeling sigma1 recepto
Publikováno v:
Journal of Medicinal Chemistry. 39:4255-4260
A series of substituted N-[(tetralin-1-yl)alkyl]piperidines and a number of related N-di-n-propyl[(tetralin-1-yl)alkyl]amines were prepared. Structural modifications such as piperidine substitutions, intermediate chain lengthening, and the nature of
Autor:
D. Conte-Camerino, Rosa Amoroso, Savina Ferorelli, Giancarlo Bettoni, A. De Luca, Fulvio Loiodice, V. Tortorella
Publikováno v:
ChemInform. 29
Publikováno v:
Minerva anestesiologica. 74(1-2)
We describe a case of severe serotonin syndrome. The patient was simultaneously taking the atypical antidepressant olanzapine and a tricyclical antidepressant, clomipramine. Symptoms included altered mental state resulting in coma, myoclonus, hyperre
Autor:
E. Vivoli, V. Tortorella, Filomena Corbo, Carlo Franchini, M. Muraglia, Carla Ghelardini, Nicoletta Galeotti, Rosanna Matucci, Giovanni Lentini
Publikováno v:
Journal of medicinal chemistry. 50(8)
Tocainide and related optically active chiral alpha-aminoanilides were synthesized and tested in vivo via the hot plate test to evaluate their central analgesic action. The aims of the study were to verify if a) the increase in lipophilicity, obtaine
Publikováno v:
British journal of pharmacology. 128(6)
1 The antiarrhythmic drug mexiletine (Mex) is also used against myotonia. Searching for a more efficient drug, a new compound (Me5) was synthesized substituting the methyl group on the chiral carbon atom of Mex by an isopropyl group. Effects of Me5 o
Publikováno v:
Journal of medicinal chemistry. 42(3)
Some 1-aryl-4-[(5-methoxy-1,2,3, 4-tetrahydronaphthalen-1-yl)-n-propyl]piperazines and their alkylamino and alkylamido analogues, previously studied as 5-HT1A ligands, were prepared in enantiomerically pure form, and their absolute configuration was