Immuno-oncological drugs application in the treatment of metastatic cutaneous melanoma with lymph nodes metastases of rare localization: a case report

Autor: A. P. Polyakov, L. V. Bolotina, A. L. Kornietskaya, D. S. Kudashkina, D. V. Sidorov, A. A. Troitskiy, A. R. Gevorkov

Publikováno v: Опухоли головы и шеи, Vol 12, Iss 1, Pp 114-119 (2022)

Cutaneous melanoma is characterized by an aggressive course associated with a tendency to metastasis. For a long time, the prognosis of patients with metastatic melanoma remained extremely poor. However, the introduction of immunooncological drugs in

Externí odkaz: https://doaj.org/article/ea24c848bd484110b4f97cd901fa2716

A Two-Week $IXPE$ Monitoring Campaign on Mrk 421

Autor: Maksym, W. Peter, Liodakis, Ioannis, Saade, M. Lynne, Kim, Dawoon E., Middei, Riccardo, Di Gesu, Laura, Kiehlmann, Sebastian, Matzeu, Gabriele, Agudo, Iván, Marscher, Alan P., Ehlert, Steven R., Jorstad, Svetlana G., Kaaret, Philip, Marshall, Herman L., Pacciani, Luigi, Perri, Matteo, Puccetti, Simonetta, Kouch, Pouya M., Lindfors, Elina, Aceituno, Francisco José, Bonnoli, Giacomo, Casanova, Víctor, Escudero, Juan, Agís-González, Beatriz, Husillos, César, Morcuende, Daniel, Otero-Santos, Jorge, Sota, Alfredo, Piirola, Vilppu, Imazawa, Ryo, Sasada, Mahito, Fukazawa, Yasushi, Kawabata, Koji S., Uemura, Makoto, Mizuno, Tsunefumi, Nakaoka, Tatsuya, Akitaya, Hiroshi, McCall, Callum, Jermak, Helen E., Steele, Iain A., Borman, George A., Grishina, Tatiana S., Hagen-Thorn, Vladimir A., Kopatskaya, Evgenia N., Larionova, Elena G., Morozova, Daria A., Savchenko, Sergey S., Shishkina, Ekaterina V., Troitskiy, Ivan S., Troitskaya, Yulia V., Vasilyev, Andrey A., Zhovtan, Alexey V., Myserlis, Ioannis, Gurwell, Mark, Keating, Garrett, Rao, Ramprasad, Pauley, Colt, Angelakis, Emmanouil, Kraus, Alexander, Berdyugin, Andrei V., Kagitani, Masato, Kravtsov, Vadim, Poutanen, Juri, Sakanoi, Takeshi, Kang, Sincheol, Lee, Sang-Sung, Kim, Sang-Hyun, Cheong, Whee Yeon, Jeong, Hyeon-Woo, Song, Chanwoo, Blinov, Dmitry, Shablovinskaya, Elena, Antonelli, Lucio Angelo, Bachetti, Matteo, Baldini, Luca, Baumgartner, Wayne H., Bellazzini, Ronaldo, Bianchi, Stefano, Bongiorno, Stephen D., Bonino, Raffaella, Brez, Alessandro, Bucciantini, Niccoló, Capitanio, Fiamma, Castellano, Simone, Cavazzuti, Elisabetta, Chen, Chien-Ting, Ciprini, Stefano, Costa, Enrico, De Rosa, Alessandra, Del Monte, Ettore, Di Lalla, Niccoló, Di Marco, Alessandro, Donnarumma, Immacolata, Doroshenko, Victor, Dovčiak, Michal, Enoto, Teruaki, Evangelista, Yuri, Fabiani, Sergio, Ferrazzoli, Riccardo, Garcia, Javier A., Gunji, Shuichi, Hayashida, Kiyoshi, Heyl, Jeremy, Iwakiri, Wataru, Karas, Vladimir, Kislat, Fabian, Kitaguchi, Takao, Kolodziejczak, Jeffery J., Krawczynski, Henric, La Monaca, Fabio, Latronico, Luca, Maldera, Simone, Manfreda, Alberto, Marin, Frédéric, Marinucci, Andrea, Massaro, Francesco, Matt, Giorgio, Mitsuishi, Ikuyuki, Muleri, Fabio, Negro, Michela, Ng, C. -Y., O'Dell, Stephen L., Omodei, Nicola, Oppedisano, Chiara, Papitto, Alessandro, Pavlov, George G., Peirson, Abel Lawrence, Pesce-Rollins, Melissa, Petrucci, Pierre-Olivier, Pilia, Maura, Possenti, Andrea, Ramsey, Brian D., Rankin, John, Ratheesh, Ajay, Roberts, Oliver J., Romani, Roger W., Sgró, Carmelo, Slane, Patrick, Soffitta, Paolo, Spandre, Gloria, Swartz, Douglas A., Tamagawa, Toru, Tavecchio, Fabrizio, Taverna, Roberto, Tawara, Yuzuru, Tennant, Allyn F., Thomas, Nicholas E., Tombesi, Francesco, Trois, Alessio, Tsygankov, Sergey S., Turolla, Roberto, Vink, Jacco, Weisskopf, Martin C., Wu, Kinwah, Xie, Fei, Zane, Silvia

X-ray polarization is a unique new probe of the particle acceleration in astrophysical jets made possible through the Imaging X-ray Polarimetry Explorer. Here we report on the first dense X-ray polarization monitoring campaign on the blazar Mrk 421.

Externí odkaz: http://arxiv.org/abs/2410.19983

Testing particle acceleration in blazar jets with continuous high-cadence optical polarization observations

Autor: Liodakis, Ioannis, Kiehlmann, Sebastian, Marscher, Alan P., Zhang, Haocheng, Blinov, Dmitry, Jorstad, Svetlana G., Agudo, Iván, Benítez, Erika, Berdyugin, Andrei, Bonnoli, Giacomo, Casadio, Carolina, Chen, Chien-Ting, Chen, Wen-Ping, Ehlert, Steven R., Escudero, Juan, Grishina, Tatiana S., Hiriart, David, Hsu, Angela, Imazawa, Ryo, Jermak, Helen E., Jose, Jincen, Kaaret, Philip, Kopatskaya, Evgenia N., Lalchand, Bhavana, Larionova, Elena G., Lindfors, Elina, López, José M., McCall, Callum, Morozova, Daria A., Palaiologou, Efthymios, Pandey, Shivangi, Poutanen, Juri, Rakshit, Suvendu, Reig, Pablo, Sasada, Mahito, Savchenko, Sergey S., Shablovinskaya, Elena, Neha, Sharma, Shrestha, Manisha, Steele, Iain A., Troitskiy, Ivan S., Troitskaya, Yulia V., Uemura, Makoto, Vasilyev, Andrey A., Weaver, Zachary, Wiersema, Klaas, Weisskopf, Martin C.

Publikováno v: A&A 689, A200 (2024)

Variability can be the pathway to understanding the physical processes in astrophysical jets, however, the high-cadence observations required to test particle acceleration models are still missing. Here we report on the first attempt to produce conti

Externí odkaz: http://arxiv.org/abs/2406.15554

The variability patterns of the TeV blazar PG 1553+113 from a decade of MAGIC and multi-band observations

Autor: MAGIC Collaboration, Abe, H., Abe, S., Abhir, J., Acciari, V. A., Agudo, I., Aniello, T., Ansoldi, S., Antonelli, L. A., Engels, A. Arbet, Arcaro, C., Artero, M., Asano, K., Baack, D., Babić, A., Baquero, A., de Almeida, U. Barres, Batković, I., Baxter, J., González, J. Becerra, Bernardini, E., Bernete, J., Berti, A., Besenrieder, J., Bigongiari, C., Biland, A., Blanch, O., Bonnoli, G., Bošnjak, Ž., Burelli, I., Busetto, G., Campoy-Ordaz, A., Carosi, A., Carosi, R., Carretero-Castrillo, M., Castro-Tirado, A. J., Chai, Y., Cifuentes, A., Cikota, S., Colombo, E., Contreras, J. L., Cortina, J., Covino, S., D'Amico, G., D'Elia, V., Da Vela, P., Dazzi, F., De Angelis, A., De Lotto, B., Del Popolo, A., Delfino, M., Delgado, J., Mendez, C. Delgado, Depaoli, D., Di Pierro, F., Di Venere, L., Prester, D. Dominis, Donini, A., Dorner, D., Doro, M., Elsaesser, D., Emery, G., Escudero, J., Fariña, L., Fattorini, A., Foffano, L., Font, L., Fukami, S., Fukazawa, Y., López, R. J. García, Gasparyan, S., Gaug, M., Paiva, J. G. Giesbrecht, Giglietto, N., Giordano, F., Gliwny, P., Grau, R., Green, J. G., Hadasch, D., Hahn, A., Heckmann, L., Herrera, J., Hovatta, T., Hrupec, D., Hütten, M., Imazawa, R., Inada, T., Iotov, R., Ishio, K., Martínez, I. Jiménez, Jormanainen, J., Kerszberg, D., Kluge, G. W., Kobayashi, Y., Kouch, P. M., Kubo, H., Kushida, J., Lezáun, M. Láinez, Lamastra, A., Leone, F., Lindfors, E., Liodakis, I., Lombardi, S., Longo, F., López-Moya, M., López-Oramas, A., Loporchio, S., Lorini, A., Fraga, B. Machado de Oliveira, Majumdar, P., Makariev, M., Maneva, G., Mang, N., Manganaro, M., Mannheim, K., Mariotti, M., Martínez, M., Martínez-Chicharro, M., Mas-Aguilar, A., Mazin, D., Menchiari, S., Mender, S., Miceli, D., Miener, T., Miranda, J. M., Mirzoyan, R., González, M. Molero, Molina, E., Mondal, H. A., Moralejo, A., Morcuende, D., Nakamori, T., Nanci, C., Neustroev, V., Nigro, C., Nikolić, L., Nilsson, K., Nishijima, K., Ekoume, T. Njoh, Noda, K., Nozaki, S., Ohtani, Y., Okumura, A., Otero-Santos, J., Paiano, S., Palatiello, M., Paneque, D., Paoletti, R., Paredes, J. M., Pavlović, D., Persic, M., Pihet, M., Pirola, G., Podobnik, F., Moroni, P. G. Prada, Prandini, E., Principe, G., Priyadarshi, C., Rhode, W., Ribó, M., Rico, J., Righi, C., Sahakyan, N., Saito, T., Satalecka, K., Saturni, F. G., Schleicher, B., Schmidt, K., Schmuckermaier, F., Schubert, J. L., Schweizer, T., Sciaccaluga, A., Sitarek, J., Spolon, A., Stamerra, A., Strišković, J., Strom, D., Suda, Y., Suutarinen, S., Tajima, H., Takeishi, R., Tavecchio, F., Temnikov, P., Terauchi, K., Terzić, T., Teshima, M., Tosti, L., Truzzi, S., Tutone, A., Ubach, S., van Scherpenberg, J., Ventura, S., Verguilov, V., Viale, I., Vigorito, C. F., Vitale, V., Walter, R., Wunderlich, C., Yamamoto, T., collaborators, MWL, Jermak, H., Steele, I. A., Smith, P. S., Blinov, D., Raiteri, C. M., Villata, M., Mirzaqulov, D. O., Kurtanidze, S. O., Carosati, D., Savchenko, S. S., Acosta-Pulido, J. A., Borman, G. A., Bozhilov, V., Carnerero, M. I., Chigladze, R. A., Damljanovic, G., Ehgamberdiev, S. A., Feige, M., Grishina, T. S., Gupta, A. C., Hagen-Thorn, V. A., Ibryamov, S., Ivanidze, R. Z., Jorstad, S. G., Kania, J., Kimeridze, G. N., Kopatskaya, E. N., Kopp, M., Kunkel, L., Kurtanidze, O. M., Larionov, V. M., Larionova, E. G., Larionova, L. V., Lorey, C., Marchini, A., Marscher, A. P., Minev, M., Morozova, D. A., Nikolashvili, M. G., Ovcharov, E., Reinhart, D., Sadun, A. C., Scherbantin, A., Schneider, L., Semkov, E., Sigua, L. A., Steineke, R., Troitskaya, Yu. V., Troitskiy, I. S., Valcheva, A., Vasilyev, A. A., Vince, O., Zaharieva, E., Zottmann, N., Kiehlmann, S., Readhead, A., Max-Moerbeck, W., Reeves, R. A., Sandrinelli, A., Ramazani, V. Fallah, Giroletti, M., Righini, S., Marchili, N., Patricelli, B., Ghirlanda, G., Lico, R.

PG 1553+113 is one of the few blazars with a convincing quasi-periodic emission in the gamma-ray band. The source is also a very high-energy (VHE; >100 GeV) gamma-ray emitter. To better understand its properties and identify the underlying physical p

Externí odkaz: http://arxiv.org/abs/2403.02159

The Repeating Flaring Activity of Blazar AO 0235+164

Autor: Pedrosa, Juan Escudero, Agudo, Iván, Tramacere, Andrea, Marscher, Alan P., Jorstad, Svetlana, Weaver, Z. R., Casadio, Carolina, Thum, Clemens, Myserlis, Ioannis, Fuentes, Antonio, Traianou, Efthalia, Kim, Jae-Young, Kramer, Joana, López-Coto, Rubén, D'Ammando, Filippo, Bernardos, M., Bonnoli, Giacomo, Blinov, Dmitriy A., Borman, G. A., Grishina, T. S., Hagen-Thorn, V. A., Kopatskaya, E. N., Larionova, E. G., Larionov, V. M., Larionova, L. V., Morozova, D. A., Savchenko, S. S., Troitskiy, I. S., Troitskaya, Y. V., Vasilyev, A. A.

Context. Blazar AO 0235+164, located at redshift z = 0.94, has undergone several sharp multi-spectral-range flaring episodes during the last decades. In particular, the episodes peaking in 2008 and 2015, that received extensive multi-wavelength cover

Externí odkaz: http://arxiv.org/abs/2311.01157