Výsledky vyhledávání - "A. A. Svidlov"

Akademický článek

Ratio of AT and GC Pairs in the Zones of Open States Genesis in DNA Molecules

Autor: Anna Dorohova, Oksana Lyasota, Alexander Svidlov, Anastasia Anashkina, Elena Tekutskaya, Stepan Dzhimak, Mikhail Drobotenko

Publikováno v: Frontiers in Bioscience-Landmark, Vol 29, Iss 11, p 381 (2024)

Background: There is an assumption about the presence of a specific nucleotides sequence in DNA molecule, which contributes to the genesis of open states (OS). In addition, it would be logical to assume that OS zones should form in DNA regions with a

Externí odkaz: https://doaj.org/article/2f606105297941d9b0b85ae4a3027a47

Zobrazit plný text záznamu

Akademický článek

Fluctuations in Medium Viscosity May Affect the Stability of the CAG Tract in the ATXN2 Gene

Autor: Anna Dorohova, Oksana Lyasota, Stepan Dzhimak, Alexandr Svidlov, Olga Leontyeva, Mikhail Drobotenko

Publikováno v: Biomedicines, Vol 12, Iss 10, p 2396 (2024)

Background: Trinucleotide repeats are the cause of many neurodegenerative diseases that are currently incurable. In this regard, the question of the causes of occurrence and methods of prevention or treatment of diseases caused by the expansion of re

Externí odkaz: https://doaj.org/article/a5d50008605f45bd93535a87e14a23f0

Zobrazit plný text záznamu

Akademický článek

Abnormal open states patterns in the ATXN2 DNA sequence depends on the CAG repeats length

Autor: Drobotenko, Mikhail I., Lyasota, Oksana M., Hernandez-Caceres, Jose Luis, Labrada, Roberto Rodriguez, Svidlov, Alexandr A., Dorohova, Аnna A., Baryshev, Mikhail G., Nechipurenko, Yury D., Pérez, Luis Velázquez, Dzhimak, Stepan S.

Publikováno v: In International Journal of Biological Macromolecules September 2024 276 Part 1

Zobrazit plný text záznamu

Akademický článek

Fluctuations in Medium Viscosity May Affect the Stability of the CAG Tract in the ATXN2 Gene.

Autor: Dorohova, Anna, Lyasota, Oksana, Dzhimak, Stepan, Svidlov, Alexandr, Leontyeva, Olga, Drobotenko, Mikhail

Publikováno v: Biomedicines; Oct2024, Vol. 12 Issue 10, p2396, 12p

Zobrazit plný text záznamu

Akademický článek

Stability of the CAG Tract in the ATXN2 Gene Depends on the Localization of CAA Interruptions

Autor: Oksana Lyasota, Anna Dorohova, Jose Luis Hernandez-Caceres, Alexandr Svidlov, Elena Tekutskaya, Mikhail Drobotenko, Stepan Dzhimak

Publikováno v: Biomedicines, Vol 12, Iss 8, p 1648 (2024)

It is known that the presence of CAA codons in the CAG tract affects the nature and time of disease onset caused by the expansion of trinucleotide repeats. The mechanisms leading to the occurrence of these diseases should be sought not only at the le

Externí odkaz: https://doaj.org/article/33bf1eb4b93a4f2ab02fd43b554f3116

Zobrazit plný text záznamu