Zobrazeno 1 - 10
of 4 658
pro vyhledávání: '"A. A. Sverdlov"'
Dose selection is critical in pharmaceutical drug development, as it directly impacts therapeutic efficacy and patient safety of a drug. The Generalized Multiple Comparison Procedures and Modeling (MCP-Mod) approach is commonly used in Phase II trial
Externí odkaz:
http://arxiv.org/abs/2410.11716
Autor:
Ryeznik, Yevgen, Sverdlov, Oleksandr
In this paper, we present Insertus.jl, the Julia package that can help the user generate a randomization sequence of a given length for a multi-arm trial with a pre-specified target allocation ratio and assess the operating characteristics of the cho
Externí odkaz:
http://arxiv.org/abs/2407.14248
Autor:
Saifei Liu, John D. Horowitz, Bogda Koczwara, Aaron L. Sverdlov, Natalie Packer, Robyn A. Clark
Publikováno v:
Cardio-Oncology, Vol 10, Iss 1, Pp 1-11 (2024)
Abstract Background The association between cardiovascular disease and carcinogenesis is bidirectional and well-established. Furthermore, cancer treatment improves overall patient survival, potentially at the cost of incremental and fatal cardiovascu
Externí odkaz:
https://doaj.org/article/80443f6f88e14947a8018773960f12af
Autor:
Kerstine Carter, Olga Kuznetsova, Volodymyr Anisimov, Johannes Krisam, Colin Scherer, Yevgen Ryeznik, Oleksandr Sverdlov
Publikováno v:
BMC Medical Research Methodology, Vol 24, Iss 1, Pp 1-22 (2024)
Abstract Background When running a randomized controlled trial (RCT), a clinical site may face a situation when an eligible trial participant is to be randomized to the treatment that is not available at the site. In this case, there are two options:
Externí odkaz:
https://doaj.org/article/6409d535618d494eb89ff5cf9a7acc55
Autor:
Illarionov, Yury Yu., Knobloch, Theresia, Uzlu, Burkay, Banshikov, Alexander G., Ivanov, Iliya A., Sverdlov, Viktor, Vexler, Mikhail I., Waltl, Michael, Wang, Zhenxing, Manna, Bibhas, Neumaier, Daniel, Lemme, Max C., Sokolov, Nikolai S., Grasser, Tibor
Graphene is a promising material for applications as a channel in graphene field-effect transistors (GFETs) which may be used as a building block for optoelectronics, high-frequency devices and sensors. However, these devices require gate insulators
Externí odkaz:
http://arxiv.org/abs/2309.11233
Autor:
Volodymyr Sverdlov, Yurii Karpenko
Publikováno v:
Біологічні студії, Vol 18, Iss 3, Pp 157-174 (2024)
The Ukrainian Polissia is a distinctive region in terms of biodiversity, with a significant number of northern and boreal species and communities, as well as Central European species in the Western Polissia. The research region stretches from west to
Externí odkaz:
https://doaj.org/article/769717cf99624b08bdafa451fce6f4c7
Autor:
Shanathan Sritharan, BMed, MPH, MHLM, Bradley Wilsmore, BSc(Hons), MBBS, PhD, John Wiggers, BA(Hons), PhD, Lloyd Butel-Simoes, BMed, Kristy Fakes, B Med Sci (Path), MPH, PhD, Michael McGee, MBBS, MHLM, Rhonda Walker, MHS, Mikaela White, B Nurs, Lucy Leigh, B MedRadSci, B Math, PhD, Nicholas Collins, BMed, Andrew Boyle, MBBS, PhD, Aaron L. Sverdlov, MBBS, PhD, Trent Williams, B Nurs, PhD
Publikováno v:
JACC: Advances, Vol 3, Iss 11, Pp 101328- (2024)
Background: Cardiovascular disease (CVD) is a leading cause of morbidity and mortality and residing in a rural and remote region is associated with an increased risk. The impact of rurality on CVD outcomes needs to be fully elucidated. Objectives: Th
Externí odkaz:
https://doaj.org/article/ddafc5a62e5c4ede90f696e11b4f260c
Autor:
Racine-Poon, Amy (AUTHOR), Praestgaard, Jens (AUTHOR), Sverdlov, Oleksandr (AUTHOR) alex.sverdlov@novartis.com
Publikováno v:
Statistics in Biopharmaceutical Research. Nov2024, p1-13. 13p. 4 Illustrations.
Autor:
Uschner, Diane1 (AUTHOR) duschner@bsc.gwu.edu, Sverdlov, Oleksandr2 (AUTHOR), Carter, Kerstine3 (AUTHOR), Chipman, Jonathan4,5 (AUTHOR), Kuznetsova, Olga6 (AUTHOR), Renteria, Jone1 (AUTHOR), Lane, Adam7 (AUTHOR), Barker, Chris8 (AUTHOR), Geller, Nancy9 (AUTHOR), Proschan, Michael10 (AUTHOR), Posch, Martin11 (AUTHOR), Tarima, Sergey12 (AUTHOR), Bretz, Frank11,13 (AUTHOR), Rosenberger, William F.14 (AUTHOR)
Publikováno v:
Statistics in Biopharmaceutical Research. Oct-Dec2024, Vol. 16 Issue 4, p405-413. 9p.
Autor:
Litwin, Sheldon E., Komtebedde, Jan, Borlaug, Barry A., Kaye, David M., Hasenfuβ, Gerd, Kawash, Rami, Hoendermis, Elke, Hummel, Scott L., Cikes, Maja, Gustafsson, Finn, Chung, Eugene S., Mohan, Rajeev C., Sverdlov, Aaron L., Swarup, Vijendra, Winkler, Sebastian, Hayward, Christopher S., Bergmann, Martin W., Bugger, Heiko, McKenzie, Scott, Nair, Ajith, Rieth, Andreas, Burkhoff, Daniel, Cutlip, Donald E., Solomon, Scott D., van Veldhuisen, Dirk J., Leon, Martin B., Shah, Sanjiv J.
Publikováno v:
In American Heart Journal December 2024 278:106-116