Zobrazeno 1 - 10
of 503
pro vyhledávání: '"A. A. Goryaev"'
Autor:
E. A. Ustyugova, M. V. Savkina, A. A. Goryaev, V. P. Bondarev, V. A. Merkulov, E. V. Melnikova
Publikováno v:
Биопрепараты: Профилактика, диагностика, лечение, Vol 19, Iss 4, Pp 206-214 (2019)
Cancer remains one of the leading causes of death. Conventional treatment methods, including radiation and chemotherapy, have limited effectiveness. Therefore, the development of novel approaches to cancer treatment is an urgent challenge. Biomedical
Externí odkaz:
https://doaj.org/article/2ce87045f1364aa9a88f4d52e4152e63
Publikováno v:
Биопрепараты: Профилактика, диагностика, лечение, Vol 19, Iss 2, Pp 72-80 (2019)
This review focuses on DNA and RNA vaccines whose potential use was first considered at the end of the 20th century. However, not a single bacterial plasmid-based or mRNA vaccine has been used since that time in public healthcare for the prevention o
Externí odkaz:
https://doaj.org/article/d3ae939836ab40ef8c05cbe24a0d75b1
Autor:
E. V. Melnikova, A. A. Goryaev, M. V. Savkina, O. V. Merkulova, A. A. Chaplenko, O. A. Rachinskaya, I. S. Semenova, G. A. Trusov, V. A. Merkulov
Publikováno v:
Биопрепараты: Профилактика, диагностика, лечение, Vol 18, Iss 3, Pp 150-160 (2018)
The intensive development of cellular technologies stipulates the introduction at the global level of medicinal products based on viable human cells, which in most countries are referred to as biomedical cell products. The authors conducted a compara
Externí odkaz:
https://doaj.org/article/51aeb52e8ae041dda03622515c700a68
Publikováno v:
Биопрепараты: Профилактика, диагностика, лечение, Vol 18, Iss 3, Pp 140-149 (2018)
Advances in ex vivo technologies of human genome editing have made it possible to develop new approaches to the treatment of genetic, oncological, infectious and other diseases, which may involve the use of biomedical cell products. However, despite
Externí odkaz:
https://doaj.org/article/8d31812f168f4b598133faa1ea672afe
Autor:
L. V. Sayapina, I. I. Khoreva, N. P. Baidalova, A. A. Goryaev, D. S. Davydov, V. P. Postupailo, V. A. Merkulov
Publikováno v:
Проблемы особо опасных инфекций, Vol 0, Iss 1, Pp 98-102 (2018)
Objective of the study is to assess and analyze the long-term data on annual control of residual virulence of Francisella tularensis 15 NIIEG vaccine strain for clarifying the value of the parameter and amending the regulatory documentation. Material
Externí odkaz:
https://doaj.org/article/32b42f7244934e77bf514a7d23eb59ae
Publikováno v:
Биопрепараты: Профилактика, диагностика, лечение, Vol 18, Iss 1, Pp 42-49 (2018)
Cholera is an acute diarrheal disease caused by toxigenic strains of Vibrio cholerae O1 and O139 serogroups. It still remains a major global healthcare problem. According to WHO, about 100,000 people die from cholera every year, despite the modern me
Externí odkaz:
https://doaj.org/article/1cdd8da308f447d494422d366e15b874
Autor:
I. V. Kasina, A. A. Goryaev, L. I. Rashchepkin, O. V. Fadeykina, T. I. Nemirovskaya, O. B. Ustinnikova, O. A. Lobovikova, S. A. Alekseeva, R. A. Volkova, A. A. Movsesyants
Publikováno v:
Биопрепараты: Профилактика, диагностика, лечение, Vol 0, Iss 4, Pp 32-38 (2018)
The article presents the results obtained in the study of a new batch of a candidate branch reference standard for live tularemic vaccine (vaccine BRS). The candidate vaccine BRS was represented by a commercial batch of a product that met all applica
Externí odkaz:
https://doaj.org/article/402089cd51bf4536ab529a98c07a863a
Autor:
I. V. Kasina, L. I. Raschepkin, A. A. Goryaev, S. A. Alekseeva, T. I. Nemirovskaya, A. A. Movsesyants
Publikováno v:
Биопрепараты: Профилактика, диагностика, лечение, Vol 16, Iss 4, Pp 253-259 (2018)
The results of the tests for the quality assessment of live tularemia vaccine under the Federal State Budgetary Institution «Scientific Centre for Expert Evaluation of Medicinal Products» of the Ministry of Health of the Russian Federation in 2011-
Externí odkaz:
https://doaj.org/article/e09f056c4d354f0db26581b3766a45d9
Publikováno v:
Проблемы особо опасных инфекций, Vol 0, Iss 2, Pp 87-91 (2015)
Investigated have been 8 cultures of Francisella tularensis strain 15 NIIEG (lyophilized in 1953, 1966, 1969, 1987, 1990, 2003, 2012, and 2013, respectively) stored at the State Collection of Microorganisms of the Scientific Center on Expertise of Me
Externí odkaz:
https://doaj.org/article/5993b3dcb2604324ae963af7405767c9
Publikováno v:
Проблемы особо опасных инфекций, Vol 0, Iss 4(110), Pp 49-52 (2011)
Worked out is the multilocus PCR test-system which makes it possible to identify Vibrio cholerae O1 strains on the basis of rfb gene detection, to determine their biovar - either Classical or El Tor by testing cas3 or rtxC genes respectively, and at
Externí odkaz:
https://doaj.org/article/6a3ca27d47714162abe9e6deab28029f