Genetically Modified DR5-Specific TRAIL Variant DR5-B Revealed Dual Antitumor and Protumoral Effect in Colon Cancer Xenografts and an Improved Pharmacokinetic Profile

Autor: Anne V. Yagolovich, Artem A. Artykov, Tatiana A. Karmakova, Maria S. Vorontsova, Andrey A. Pankratov, Alexander A. Andreev-Andrievsky, Dmitry A. Dolgikh, Mikhail P. Kirpichnikov, Marine E. Gasparian

Publikováno v: Translational Oncology, Vol 13, Iss 4, Pp - (2020)

Despite the weak clinical efficacy of TRAIL death receptor agonists, a search is under way for new agents that more efficiently activate apoptotic signaling. We previously created a TRAIL DR5-selective variant DR5-B without affinity for the DR4, DcR1

Externí odkaz: https://doaj.org/article/c1516f30f4fe485cbf6d4dab2de65f2c

[Mechanisms of the wound-healing action of native collagen type I in ischemic model full-thickness skin wounds on the example - medical devices Collost «(part I)]

Autor: A A Bolgarina, Vasily N. Manskikh, O V Fadeeva, R B Gabitov, E A Lagereva, A A Andreev-Andrievsky, E V Telyatnikova, V S Shcherbakova

Publikováno v: Khirurgiia. (10)

Active collagen type I successfully used in regenerative medicine. However, despite the large amount of material of cellular and molecular mechanisms underlying skin repair, the molecular mechanisms of wound healing with use collagen type I, not stud

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5396a8ba9c7ae00ee08991a6748194e
https://pubmed.ncbi.nlm.nih.gov/33047590

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Hypertension - experimental models

Autor: S. Clotet, M. J. Soler, M. Rebull, J. Pascual, M. Riera, A. G. Kucher, M. M. Parastaeva, O. N. Beresneva, G. T. Ivanova, M. I. Zaraysky, A. V. Artemeva, I. G. Kaukov, A. V. Smirnov, M. Roszkowska-Chojecka, A. Walkowska, O. Gawrys, K. Olszynski, E. Kompanowska-Jezierska, I. Baranowska, E. M. Kompanowska-Jezierska, M. M. Roszkowska-Chojecka, L. Dobrowolski, B. Badzynska, K. H. Olszynski, A. W. Lipkowski, J. Sadowski, Y. Kobayashi, N. Hirawa, Y. Okuyama, M. Fujita, A. Fujiwara, S. Saka, K. Yatsu, Y. Toya, G. Yasuda, S. Umemura, E. B. Oliveira-Sales, E. Maquigussa, P. Semedo, L. G. Pereira, N. O. S. Camara, C. T. Bergamaschi, R. R. Campos, M. A. Boim, M. A. Potenza, V. Sirolli, F. Addabbo, N. Di Pietro, L. Amoroso, C. Pipino, A. Pandolfi, M. Montagnani, M. Bonomini, Y. J. Quiroz, M. Rivero, K. Yaguas, L. Moran, B. Rodriguez-Iturbe, J. Lee, N. J. Heo, S. Kim, K. W. Joo, J. S. Han, W. Rapp, S. Raab, U. Sprecher, J. Funk, C. M. Apfel, K. Conde-Knape, Y. Qin, L. Mou, X. Li, M. E. Ilatovskaya, A. A. Andreev-Andrievsky, V. F. Pozdnev, A. V. Iliyn, N. A. Medvedeva, J. Malyszko, E. Koc-Zorawska, E. Zbroch, J. S. Malyszko, M. Zorawski, M. Mysliwiec, H. Wakui, K. Tamura, S.-i. Masuda, Y. Tsurumi-Ikeya, T. Kanaoka, T. Fujikawa, S. Suzuki, M. Yabana, S. Iimuro, E. Imai, S. Matsuo, T. Watanabe, K. Nitta, T. Akizawa, H. Makino, Y. Ohashi, A. Hishida

Publikováno v: Nephrology Dialysis Transplantation. 28:i325-i330

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::01eba968bd55541bb29f5ead1c91572e
https://doi.org/10.1093/ndt/gft128

[Experimental studies with mice on the program of the biosatellite BION-M1 mission]

Autor: Aa, Andreev-Andrievsky, Elizabeth Shenkman, As, Popova, On, Dolguikh, Kv, Anokhin, Pe, Soldatov, Ea, Ilyin, Vn, Sychev

Publikováno v: Europe PubMed Central

Purpose of the BION-M1 project was laying the evidence and technological basis for addressing the medical issues of future remote space exploration missions by humans. The program of researches with the use of mice was focused on elicitation of cellu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::9ee9f7be940fa042efde8931e1ab589a
https://pubmed.ncbi.nlm.nih.gov/25033610