Zobrazeno 1 - 10
of 2 394
pro vyhledávání: '"A. A Spasov"'
Publikováno v:
Research Results in Pharmacology 10(1): 1-6 (2024)
Introduction: Kappa-opioid receptor (KOR) signaling in the basolateral amygdala (BLA) underlies KOR agonist-induced aversion. In this study, we aimed to understand the individual and combined effects of KOR agonist U-50488 and p38 MAPK inhibitor SB20
Externí odkaz:
http://arxiv.org/abs/2402.05815
Autor:
Dimitri, Giovanna Maria, Spasov, Simeon, Duggento, Andrea, Passamonti, Luca, Li`o, Pietro, Toschi, Nicola
Recently, it has become progressively more evident that classic diagnostic labels are unable to reliably describe the complexity and variability of several clinical phenotypes. This is particularly true for a broad range of neuropsychiatric illnesses
Externí odkaz:
http://arxiv.org/abs/2303.15963
Publikováno v:
Folia Medica, Vol 66, Iss 3, Pp 421-425 (2024)
In recent years, the role of radiation oncology in treating various pediatric cancers has been extensively researched and developed. The dosage of radiotherapy, when combined with chemotherapy, was either reduced in some oncological diseases or modif
Externí odkaz:
https://doaj.org/article/de876211573a445fa65a474e6a32b983
Autor:
Olga N. Zhukovskaya, Natalya V. Eliseeva, Pavel M. Vassiliev, Gleb V. Pridvorov, Olesya Yu. Grechko, Anatoly S. Morkovnik, Alexander A. Spasov
Publikováno v:
Research Results in Pharmacology, Vol 10, Iss 2, Pp 119-133 (2024)
Introduction: The creation of new opioid analgesics that are devoid of the main undesirable effects – euphoria, respiratory depression, tolerance – is an important task for the treatment of pain syndrome. Eighteen salts of 9-pyrrolidinoethyl-(1a)
Externí odkaz:
https://doaj.org/article/16cc6b6bf0cf4b1b9e72fe962ebf69f9
Graphs are a natural representation of brain activity derived from functional magnetic imaging (fMRI) data. It is well known that clusters of anatomical brain regions, known as functional connectivity networks (FCNs), encode temporal relationships wh
Externí odkaz:
http://arxiv.org/abs/2301.11408
Autor:
Delgado, Jorge, Koev, Plamen, Marco, Ana, Martinez, Jose-Javier, Pena, Juan Manuel, Persson, Per-Olof, Spasov, Steven
We present a method to derive new explicit expressions for bidiagonal decompositions of Vandermonde and related matrices such as the (q-, h-) Bernstein-Vandermonde ones, among others. These results generalize the existing expressions for nonsingular
Externí odkaz:
http://arxiv.org/abs/2210.10148
In medicine, curated image datasets often employ discrete labels to describe what is known to be a continuous spectrum of healthy to pathological conditions, such as e.g. the Alzheimer's Disease Continuum or other areas where the image plays a pivota
Externí odkaz:
http://arxiv.org/abs/2209.12279
The lack of large labeled medical imaging datasets, along with significant inter-individual variability compared to clinically established disease classes, poses significant challenges in exploiting medical imaging information in a precision medicine
Externí odkaz:
http://arxiv.org/abs/2209.12005
Autor:
D. A. Babkov, A. S. Taran, A. A. Shevchenko, L. V. Naumenko, O. N. Zhukovskaya, A. M. Efremov, E. N. Bezsonova, N. A. Lozinskaya, A. A. Spasov
Publikováno v:
Acta Biomedica Scientifica, Vol 9, Iss 1, Pp 116-128 (2024)
Background. Melatonin is an endogenous regulator of intraocular pressure (IOP), but its effectiveness as a drug for glaucoma treatment is limited.The aim of the study. To develop and to validate a virtual screening method to identify bioisosteric ana
Externí odkaz:
https://doaj.org/article/f1d1f8168ad943f3b9de3398ea2a659c
Autor:
Antonets, Anastasia A., Spitsyna, Ekaterina V., Tyurin, Vladimir Yu., Mazur, Dmitrii M., Yakovlev, Dmitry S., Babkov, Denis A., Pshenichnikova, Mariya S., Spasov, Alexander A., Milaeva, Elena R., Nazarov, Alexey A.
Publikováno v:
In Journal of Inorganic Biochemistry January 2025 262