Výsledky vyhledávání - "A. Umriukhin"

Akademický článek

Dose-Response Effect of Various Concentrations of Cl-Containing Water-Soluble Derivatives of C60 Fullerenes on a Selective Regulation of Gene Expression in Human Embryonic Lung Fibroblasts (HELF)

Autor: Svetlana V. Kostyuk, Elena M. Malinovskaya, Pavel E. Umriukhin, Elena N. Mikheeva, Elizaveta S. Ershova, Ekaterina A. Savinova, Larisa V. Kameneva, Pavel A. Troshin, Olga A. Kraevaya, Ivan V. Rodionov, Svetlana E. Kostyuk, Tatyana A. Salimova, Sergey I. Kutsev, Natalia N. Veiko

Publikováno v: Frontiers in Bioscience-Landmark, Vol 29, Iss 10, p 352 (2024)

Background: The new synthesized water-soluble derivatives of C60 fullerenes are of a great interest to researchers since they can potentially be promising materials for drug delivery, bioimaging, biosonding, and tissue engineering. Surface functional

Externí odkaz: https://doaj.org/article/2e1e21d53a374970a98361ecfc195cd8

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Akademický článek

Impact of Serotonin Transporter Absence on Brain Insulin Receptor Expression, Plasma Metabolome Changes, and ADHD-like Behavior in Mice fed a Western Diet

Autor: Daniel C. Anthony, Fay Probert, Anna Gorlova, Jenna Hebert, Daniel Radford-Smith, Zlata Nefedova, Aleksei Umriukhin, Andrey Nedorubov, Raymond Cespuglio, Boris Shulgin, Aleksey Lyundup, Klaus Peter Lesch, Tatyana Strekalova

Publikováno v: Biomolecules, Vol 14, Iss 8, p 884 (2024)

The impaired function of the serotonin transporter (SERT) in humans has been linked to a higher risk of obesity and type 2 diabetes, especially as people age. Consuming a “Western diet” (WD), which is high in saturated fats, cholesterol, and suga

Externí odkaz: https://doaj.org/article/2b9262aba5ef4959863634dd07723836

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Akademický článek

Lipopolysaccharide triggers exacerbated microglial activation, excessive cytokine release and behavioural disturbances in mice with truncated Fused-in-Sarcoma Protein (FUS)

Autor: Alexander Trofimov, Dmitrii Pavlov, Anand Goswami, Anna Gorlova, Kirill Chaprov, Aleksei Umriukhin, Allan Kalueff, Alexey Deykin, Klaus-Peter Lesch, Daniel Clive Anthony, Tatyana Strekalova

Publikováno v: Brain, Behavior, & Immunity - Health, Vol 33, Iss , Pp 100686- (2023)

CNS inflammation, including microglial activation, in response to peripheral infections are known to contribute to the pathology of both familial and sporadic neurodegenerative disease. The relationship between Fused-in-Sarcoma Protein (FUS)-mediated

Externí odkaz: https://doaj.org/article/80e012cd55704c19bdc25c3f316432fc

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Akademický článek

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Akademický článek

Ribosomal, Telomere, and Mitochondrial Repeat Copy Number Variations in Female Genomes during Ovarian Stimulation and the Prediction of In Vitro Fertilization Outcome: A Pilot Study

Autor: Natalia Nikolaevna Veiko, Elizaveta Sergeevna Ershova, Lev Nikolaevich Porokhovnik, Maria Petrovna Klimenko, Peter Afanasievich Klimenko, Pavel Evgenievich Umriukhin, Еdmund Viktorovich Kostyuk, Mark Arkadievich Kurtser, Oksana Nikolaevna Agafonova, Tatyana Agaragimovna Salimova, Sergey Ivanovich Kutsev, Vera Leonidovna Izhevskaya, Svetlana Viktorovna Kostyuk

Publikováno v: Frontiers in Bioscience-Scholar, Vol 15, Iss 3, p 9 (2023)

Introduction: Individual risk assessment of assisted reproductive technologies is essential for personalized treatment strategies. Genetic and genomic indicators of the response to stress by cells could provide individual prognostic indicators for in

Externí odkaz: https://doaj.org/article/87b291689d6d4e90ad03fd739d65a68b

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Akademický článek

Oxidized Cell-Free DNA Rapidly Skews the Transcriptional Profile of Brain Cells toward Boosting Neurogenesis and Neuroplasticity

Autor: Anton D. Filev, Svetlana V. Kostyuk, Pavel E. Umriukhin, Vladimir M. Pisarev

Publikováno v: Current Issues in Molecular Biology, Vol 43, Iss 3, Pp 1583-1591 (2021)

Cell-free DNA (cfDNA) is liberated and accumulated in neural tissue due to cell damage. The oxidative and nitrosative stress in the brain that accompanies various pathological conditions has been shown to increase the oxidation of cellular and cell-f

Externí odkaz: https://doaj.org/article/31c52e51946a4a27b24b18a495462092

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Akademický článek

Mild cognitive impairment is associated with low copy number of ribosomal genes in the genomes of elderly people

Autor: Natalia N. Veiko, Elizaveta S. Ershova, Roman V. Veiko, Pavel E. Umriukhin, Marat V. Kurmyshev, Georg P. Kostyuk, Sergey I. Kutsev, Svetlana V. Kostyuk

Publikováno v: Frontiers in Genetics, Vol 13 (2022)

Introduction: Mild cognitive impairments (MCI) accompanying aging are associated with oxidative stress. The ability of cells to respond to stress is determined by the protein synthesis level, which depends on the ribosomes number. Ribosomal deficit w

Externí odkaz: https://doaj.org/article/2469864b4a2c4dc3b31bfb3bca208572

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Akademický článek

Immunomodulatory effects of new phytotherapy on human macrophages and TLR4- and TLR7/8-mediated viral-like inflammation in mice

Autor: Olesia Schapovalova, Anna Gorlova, Johannes de Munter, Elisaveta Sheveleva, Mikhail Eropkin, Nikita Gorbunov, Michail Sicker, Aleksei Umriukhin, Sergiy Lyubchyk, Klaus-Peter Lesch, Tatyana Strekalova, Careen A. Schroeter

Publikováno v: Frontiers in Medicine, Vol 9 (2022)

BackgroundWhile all efforts have been undertaken to propagate the vaccination and develop remedies against SARS-CoV-2, no satisfactory management of this infection is available yet. Moreover, poor availability of any preventive and treatment measures

Externí odkaz: https://doaj.org/article/86489358180a4a7399457cebf2d4d4a3

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