Synthesis, Spectroscopic Analysis and Assessment of the Biological Activity of New Hydrazine and Hydrazide Derivatives of 3-Formylchromone

Autor: Krzysztof Słomiak, Andrzej Łazarenkow, Lilianna Chęcińska, Joachim Kusz, Justyn Ochocki, Jolanta Nawrot-Modranka

Publikováno v: Molecules, Vol 23, Iss 8, p 2067 (2018)

The hydrazine and hydrazide derivatives of benzo-γ-pyrones with fluorine substituents remain an unexplored group of chemical compounds. This preliminary study reports the synthesis, structural assessment, initial microbiological screening and biolog

Externí odkaz: https://doaj.org/article/7e9def62fe244807ad8c6b0be68e5fd5

Synthesis, Spectroscopic Analysis and Assessment of the Biological Activity of New Hydrazine and Hydrazide Derivatives of 3-Formylchromone

Autor: Justyn Ochocki, Joachim Kusz, Krzysztof Słomiak, Lilianna Chęcińska, Jolanta Nawrot-Modranka, Andrzej Łazarenkow

Publikováno v: Molecules : A Journal of Synthetic Chemistry and Natural Product Chemistry
Molecules, Vol 23, Iss 8, p 2067 (2018)
Molecules
Volume 23
Issue 8

The hydrazine and hydrazide derivatives of benzo-&gamma
pyrones with fluorine substituents remain an unexplored group of chemical compounds. This preliminary study reports the synthesis, structural assessment, initial microbiological screening a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76a23c82100006aabb8a3340f68906fc
https://pubmed.ncbi.nlm.nih.gov/30126150

Synthesis, preliminary cytotoxicity evaluation of new 3-formylchromone hydrazones and phosphorohydrazone derivatives of coumarin and chromone

Autor: M. Różalski, U. Krajewska, E. Brzezińska, A. Łazarenkow, J. Nawrot-Modranka

Publikováno v: Medicinal Chemistry Research. 21:1861-1868

Reactions of chromone derivatives 1–4 with N-substituted hydrazines were described. Hydrazones (6, 7a, 8a–c, 9b–e, 10e, 11e, 12) were evaluated for cytotoxicity (MTT test) against HL-60 and NALM-6 leukemia cells. Phosphorohydrazone of 3-formylc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::372be9225dce52e6252e346d0ef31926
https://doi.org/10.1007/s00044-011-9703-4

The influence of chromone based hydrazones on lipid peroxidation and bFGF concentration in the HL-60 cell line

Autor: Aleksandra Piechota-Polanczyk, Andrzej Łazarenkow, Marek Mirowski, Anna Gorąca, Jolanta Nawrot-Modranka, Marta Michalska

Publikováno v: Scopus-Elsevier

Natural and synthetic derivatives of benzo-γ-pyrones (i.e. flavones, chromones, and coumarins) and their synthetic analogues possess a wide range of biological properties in vitro and in vivo. In this paper we investigated the influence of two hydra

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::568f1806efa7f640f4a4794a2cf418bd
https://pubmed.ncbi.nlm.nih.gov/23757450

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