Zobrazeno 1 - 10 of 12 pro vyhledávání: '"A-M. C. Dingemans"'
1
Akademický článek
Early Loss of Fat Mass During Chemoradiotherapy Predicts Overall Survival in Locally Advanced Squamous Cell Carcinoma of the Lung, but Not in Locally Advanced Squamous Cell Carcinoma of the Head and Neck
Autor: A. C. H. Willemsen, J. H. R. J. Degens, L. W. J. Baijens, A-M. C. Dingemans, A. Hoeben, F. J. P. Hoebers, D. K. M. De Ruysscher, A. M. W. J. Schols
Publikováno v: Frontiers in Nutrition, Vol 7 (2020)
Background: Cancer cachexia is highly prevalent in advanced non-small cell lung cancer (NSCLC) and locally advanced head and neck squamous cell carcinoma (LAHNSCC), and compromises treatment tolerance and overall survival (OS). NSCLC and LAHNSCC pati
Externí odkaz: https://doaj.org/article/7ecdaf9223d94f939be8668d6b57f480
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2
Akademický článek
Large cell neuroendocrine carcinoma with a solitary brain metastasis and low Ki-67: a unique subtype
Autor: B C M Hermans, J L Derks, H J M Groen, J A Stigt, R J van Suylen, L M Hillen, E C van den Broek, E J M Speel, A-M C Dingemans
Publikováno v: Endocrine Connections, Vol 8, Iss 12, Pp 1600-1606 (2019)
Introduction: Stage IV large cell neuroendocrine carcinoma (LCNEC) of the lung generally presents as disseminated and aggressive disease with a Ki-67 proliferation index (PI) 40–80%. LCNEC can be subdivided in two main subtypes: the first harboring
Externí odkaz: https://doaj.org/article/72a03e609bec496c9e62c8012b2c040a
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3
Topoisomerase IIα and other drug resistance markers in advanced non-small cell lung cancer
Autor: Paul van der Valk, Pieter E. Postmus, Simone W. Span, Jannette van Ark-Otte, Giuseppe Giaccone, A.-M. C. Dingemans, Giorgio V. Scagliotti
Publikováno v: Lung Cancer. 32:117-128
Resistance to chemotherapy is common in non-small cell lung cancer. The aim of this study was to investigate the prognostic impact of in vitro established drug resistance markers on the response to chemotherapy in patients with advanced non-small cel
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f8cdc4c15c9ee4c1851300eb02ece62
https://doi.org/10.1016/s0169-5002(00)00224-5
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4
Determinants of CPT-11 and SN-38 activities in human lung cancer cells
Autor: Marc A. Kedde, H.M. Pinedo, W. J. M. Jansen, W.J.F. van der Vijgh, Epie Boven, J. van Ark-Otte, G. Giaccone, A.-M. C. Dingemans
Publikováno v: British Journal of Cancer
Scopus-Elsevier
Irinotecan (CPT-11) is a semisynthetic camptothecin derivative with a broad spectrum of anti-tumour activity. Carboxylesterase (CE) catalyses the conversion of CPT-11 to SN-38 (7-ethyl-10-hydroxycamptothecin), the active form of CPT-11. The antiproli
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98836466550d1a225bf88c5f4cb5fb17
http://europepmc.org/articles/PMC2150393
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5
MRP is frequently expressed in human lung-cancer cell lines, in non-small-cell lung cancer and in normal lung
Autor: Herbert M. Pinedo, Rik J. Scheper, A.-M. C. Dingemans, M. J. Flens, Adi F. Gazdar, Giuseppe Giaccone, G. Rubio, Jannette van Ark-Otte, Henk J. Broxterman
Publikováno v: International Journal of Cancer. 66:760-767
The multidrug resistance-associated protein (MRP), a new membrane transporter related to non-Pgp multidrug resistance, is overexpressed in some drug-selected cancer-cell lines. The role of MRP in unselected cell lines and in human cancer is unknown.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d0fb8c0ff8355aa2fedd0a783427d755
https://doi.org/10.1002/(sici)1097-0215(19960611)66:6<760::aid-ijc9>3.0.co
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7
Expression of the human major vault protein LRP in human lung cancer samples and normal lung tissues
Autor: R.J. Scheper, P. van der Valk, R. M. Apolinario, A.-M. C. Dingemans, J. van Ark-Otte, G. Giaccone, Pieter E. Postmus
Publikováno v: Scopus-Elsevier
Summary Background: The recently discovered LRP protein has been shown to be involved in drug resistance and possibly in detoxification processes. Materials and methods: To study the relation between LRP expression and exposure to cigarette smoke, LR
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfb59d55260b9e79aa3bd4c527c41923
https://pubmed.ncbi.nlm.nih.gov/8879378
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8
120 Expression of lung resistance-related protein (LRP) in lung cancer
Autor: A.-M. C. Dingemans, Pieter E. Postmus, G. Giaccone, P. van der Valk, J. van Ark-Otte, R.J. Scheper
Publikováno v: European Journal of Cancer. 31:S28-S29
Expression of LRP seems to be of prognostic relevance in advanced ovarian cancer and acute myeloid leukemia. In this study we evaluated the expression of LRP in lung tumor samples derived from patients and its relation to survival, tumor differentiat
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b0aa336a3c16d3e73af4225035f1de15
https://doi.org/10.1016/0959-8049(95)95375-g
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9
Prognostic value of the expression of p53, bcl-2, and box oncoproteins, and neovascularization in patients with radically resected non-small-cell lung cancer
Autor: P. van der Valk, Pieter E. Postmus, Walter Devillé, A.-M. C. Dingemans, J. S. De Jong, H.M. Pinedo, J. van Ark-Otte, J. C. Van Mourik, Giuseppe Giaccone, R. M. Apolinario
Publikováno v: Scopus-Elsevier
PURPOSE To assess the prognostic value of p53, bcl-2, bax, and neovascularization in radically resected non-small-cell lung cancer (NSCLC) patients. PATIENTS AND METHODS Tumors from 116 patients were assessed by immunohistochemistry for expression of
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1f3f6ff113ff4463e347722fa5b84f0
http://www.scopus.com/inward/record.url?eid=2-s2.0-0030940210&partnerID=MN8TOARS
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10
Akademický článek
Integrative and comparative genomic analyses identify clinically relevant pulmonary carcinoid groups and unveil the supra-carcinoids
Autor: N. Alcala, N. Leblay, A. A. G. Gabriel, L. Mangiante, D. Hervas, T. Giffon, A. S. Sertier, A. Ferrari, J. Derks, A. Ghantous, T. M. Delhomme, A. Chabrier, C. Cuenin, B. Abedi-Ardekani, A. Boland, R. Olaso, V. Meyer, J. Altmuller, F. Le Calvez-Kelm, G. Durand, C. Voegele, S. Boyault, L. Moonen, N. Lemaitre, P. Lorimier, A. C. Toffart, A. Soltermann, J. H. Clement, J. Saenger, J. K. Field, M. Brevet, C. Blanc-Fournier, F. Galateau-Salle, N. Le Stang, P. A. Russell, G. Wright, G. Sozzi, U. Pastorino, S. Lacomme, J. M. Vignaud, V. Hofman, P. Hofman, O. T. Brustugun, M. Lund-Iversen, V. Thomas de Montpreville, L. A. Muscarella, P. Graziano, H. Popper, J. Stojsic, J. F. Deleuze, Z. Herceg, A. Viari, P. Nuernberg, G. Pelosi, A. M. C. Dingemans, M. Milione, L. Roz, L. Brcic, M. Volante, M. G. Papotti, C. Caux, J. Sandoval, H. Hernandez-Vargas, E. Brambilla, E. J. M. Speel, N. Girard, S. Lantuejoul, J. D. McKay, M. Foll, L. Fernandez-Cuesta
Publikováno v: Nature Communications, Vol 10, Iss 1, Pp 1-21 (2019)
The worldwide incidence of pulmonary carcinoids is increasing, but little is known about their molecular characteristics. Here, Alcala and colleagues present a multi-omics analysis of these tumours, revealing distinct molecular and prognostic subgrou
Externí odkaz: https://doaj.org/article/d910423db1664141b7a3767146ac820a
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