Pharmacokinetic Model of Tenofovir and Emtricitabine and Their Intracellular Metabolites in Patients in the ANRS 134-COPHAR 3 Trial Using Dose Records

Autor: Julie Bertrand, Aurélie Barrail-Tran, Lucie Fayette, Rada Savic, Cécile Goujard, Elina Teicher, Caroline Barau, Alain Pruvost, Anne-Marie Taburet, France Mentré, Céline Verstuyft, A. Barrail-Tran, A. Brunet, M.-J. Commoy, S. Couffin-Cadiergues, D. Descamps, X. Duval, C. Goujard, C. Le Guellec, F. Mentré, G. Nembot, A.-M. Taburet, B. Vrijens, •• Ajana, •• Aissi, •• Baclet, •• Besnier, •• Bollens, •• Boulanger, •• Brochier, •• Brunet, •• Chaix, •• Ciuchete, •• Ghosn, •• Duval, •• Ferret, •• Gaubin, •• Goujard, •• Girard, •• Kouadio, •• Lupin, •• Parienti, •• Parrinello, •• Poinçon de la Blanchardière, •• May, •• Marien, •• Medintzeff, •• Metivier, •• Mole, •• Molina, •• Nau, •• Ouazene, •• Pintado, •• Quertainmont, •• Ramani, •• Rami, •• Sellier, •• Simon, •• Talbi, •• Thoirain, •• Verdon, •• Trépo, •• Wassoumbou, •• Yazdanpanah, •• Barrail-Tran, •• Gagneux, •• Delhotal, •• Hoizey, •• Houdret, •• Leguellec, •• Peytavin, •• Poirier, •• Sauvageon, •• Taburet, •• André, •• Soulié, •• Calvez, •• Morand-Joubert, •• Harchi, •• Bocket, •• Mourez, •• Palmer, •• Pallier, •• Deschamps, •• Mazeron, •• Bolmann, •• Storto, •• Thanh Thuy, G. Unal, X. Panhard, R. Savic

Publikováno v: Antimicrobial Agents and Chemotherapy. 67

Tenofovir (TFV) and emtricitabine (FTC) are part of the recommended highly active antiretroviral therapy (ART). Both molecules show a large interindividual pharmacokinetic (PK) variability.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::79edc80bf1b79fa9ec9c15a7af7db223
https://doi.org/10.1128/aac.02339-18

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Levels of fusidic acid in skin blister fluid and serum after repeated administration of two dosages (250 and 500 mg)

Autor: H. Sorensen, Loïc Vaillant, A. M. Taburet, Gérard Lorette, Laurent Machet

Publikováno v: Scopus-Elsevier

The fusidic acid steady-state concentrations in serum (S) and skin suction blister fluid (SBF) after oral doses of 250 and 500 mg administered twice daily for 6 days, as film-coated tablets of sodium fusidate, were studied in eight healthy subjects.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d09356edaf1c90b2e36ab30d81761ce3
https://doi.org/10.1111/j.1365-2133.1992.tb00105.x

Worsening pneumonitis due to a pharmacokinetic drug-drug interaction between everolimus and voriconazole in a renal transplant patient

Autor: H. François, P. Eloy, C. Lecefel, Benjamin Wyplosz, A.-M. Taburet, V. Amilien, B. Chauvin, L. Massias, V. Furlan

Publikováno v: Journal of clinical pharmacy and therapeutics. 40(1)

Summary What is known and objective Azole antifungals, prescribed prophylactically to avoid severe infections in immunosuppressed organ transplant recipients, can interact with drug substrates of CYP3A4. We report serious adverse effects due to inter

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a750a7fee34724866ed9565bd6947e46
https://pubmed.ncbi.nlm.nih.gov/25417855

Pharmacokinetics of rifampin and isoniazid in tuberculosis-HIV-coinfected patients receiving nevirapine- or efavirenz-based antiretroviral treatment

Autor: N B, Bhatt, C, Barau, A, Amin, E, Baudin, B, Meggi, C, Silva, V, Furlan, B, Grinsztejn, A, Barrail-Tran, M, Bonnet, A M, Taburet, Christine, Rouzioux

Publikováno v: Antimicrobial agents and chemotherapy. 58(6)

This is a substudy of the Agence Nationale de Recherches sur le Sida et les Hépatites Virales (ANRS) Comparison of Nevirapine and Efavirenz for the Treatment of HIV-TB Co-infected Patients (ANRS 12146-CARINEMO) trial, which assessed the pharmacokine

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6871634ce3b92917ca12fccec618380
https://pubmed.ncbi.nlm.nih.gov/24663014