Effect of A-769662, a direct AMPK activator, on Tlr-4 expression and activity in mice heart tissue

Autor: Maryam Rameshrad, Nasrin Maleki-Dizaji, Hamid Soraya, Negisa Seyed Toutounchi, Abolfazl Barzegari, Alireza Garjani

Publikováno v: Iranian Journal of Basic Medical Sciences, Vol 19, Iss 12, Pp 1308-1317 (2016)

Objective(s): TLR-4 activates a number of inflammatory signaling pathways. Also, AMPK could be involved in anti-inflammatory signaling. The aim of this study was to identify whether stimulation of AMPK could inhibit LPS-induced Tlr-4 gene expression

Externí odkaz: https://doaj.org/article/f655effc9910457c86ac31cce8008040

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AMPK-dependent activation of the Cyclin Y/CDK16 complex controls autophagy

Autor: Elena Buerova, Kei Sakamoto, Christian Preisinger, Bernhard Lüscher, Jörg Vervoorts, Mareike Bütepage, Sarah Krieg, Stephan Geley, Dipanjan Chanda, Carolina M. Pfaff, Marc Dohmen, Georgios Agalaridis, Saifeldin N. Shehata, Xiaoqing Zhu, Jan Amelang, Elisabeth Pfeiffenberger, Dietbert Neumann

Publikováno v: Nature Communications, 11(1):1032. Nature Publishing Group
Dohmen, M, Krieg, S, Agalaridis, G, Zhu, X, Shehata, S N, Pfeiffenberger, E, Amelang, J, Bütepage, M, Buerova, E, Pfaff, C M, Chanda, D, Geley, S, Preisinger, C, Sakamoto, K, Lüscher, B, Neumann, D & Vervoorts, J 2020, ' AMPK-dependent activation of the Cyclin Y/CDK16 complex controls autophagy ', Nature Communications, vol. 11, no. 1, 1032 . https://doi.org/10.1038/s41467-020-14812-0
Nature Communications
Nature Communications, Vol 11, Iss 1, Pp 1-18 (2020)

The AMP-activated protein kinase (AMPK) is a master sensor of the cellular energy status that is crucial for the adaptive response to limited energy availability. AMPK is implicated in the regulation of many cellular processes, including autophagy. H

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a596c455e15e84047461fa9d0ca10bb8
https://lirias.kuleuven.be/handle/20.500.12942/716305

New insights in the AMPK regulation in chicken spermatozoa: Role of direct AMPK activator and relationship between AMPK and PKA pathways

Autor: Isabelle Grasseau, Elisabeth Blesbois, Thi Mong Diep Nguyen

Publikováno v: Theriogenology
Theriogenology, Elsevier, 2019, 140, pp.1-7. ⟨10.1016/j.theriogenology.2019.07.031⟩

International audience; Energy balance is an important feature for spermatozoa functions. The 5'-AMP-activated protein kinase (AMPK), a sensor of cell energy, has been implicated as a mediator between spermatozoa functions and energy balance. We rece

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60f42fce859f4fe14e2619f4ec24163a
https://pubmed.ncbi.nlm.nih.gov/31419697

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