Zobrazeno 1 - 10
of 25
pro vyhledávání: '"A W Wyke"'
Publikováno v:
European Journal of Biochemistry. 127:553-558
The cell-wall composition and degree of cross-linking of peptidoglycan in a strain of Staphylococcus aureus (strain MR-1) which is highly resistant to methicillin were similar to those of other strains of S. aureus. When the organism was grown in the
Autor:
Richard Jones, Valerie G. Brunton, Anne W. Wyke, Margaret C. Frame, David G.C. Owens, Egle Avizienyte
Publikováno v:
British Journal of Cancer
Elevated expression and/or activity of c-Src, the prototype of the Src family of protein tyrosine kinases, is associated with the development of human colon cancer. However, despite the known pleiotropic effects of these kinases in promoting (a) cell
Autor:
D W Owens, Valerie G. Brunton, A W Wyke, G W McLean, Eric Kenneth Parkinson, Margaret C. Frame, C Paraskeva
Publikováno v:
Molecular Biology of the Cell. 11:51-64
Despite the importance of epithelial cell contacts in determining cell behavior, we still lack a detailed understanding of the assembly and disassembly of intercellular contacts. Here we examined the role of the catalytic activity of the Src family k
Autor:
Anne W. Wyke, Valerie G. Brunton, Gordon W. McLean, Robert Jones, Margaret C. Frame, Egle Avizienyte, M. Andrew Westhoff
Publikováno v:
Nature cell biology. 4(8)
Although Src expression and activity are often elevated in colon cancer, the precise consequences of overexpression of the non-catalytic Src homology (SH) domains, or enhanced catalytic activity, are unknown. We show that, in KM12C colon cancer cells
Publikováno v:
Cancer research. 61(23)
Although focal adhesion kinase (FAK) is elevated in epithelial cancers, it is not known whether FAK expression influences tumor development in vivo. We found that fak +/- heterozygous mice display reduced 7,12-dimethylbenz[a]anthracene-induced papill
Publikováno v:
Cell growthdifferentiation : the molecular biology journal of the American Association for Cancer Research. 4(8)
Activation of the tyrosine kinase of a temperature sensitive v-Src mutant of Rous sarcoma virus in quiescent Rat-1 cells leads to passage through the cell cycle. This is accompanied by a transient increase of the DNA binding activity of the transcrip
Publikováno v:
Cellular signalling. 4(3)
When Rat-1 cells bearing the ts LA29 mutant of Rous sarcoma virus (Rat1 LA29) are shifted from restrictive to permissive temperature, the pp60v-Src tyrosine kinase is activated and there is an increase in the cellular level of sn1,2-diacylglycerol (D
Publikováno v:
Oncogene. 5(2)
Rat-1 cells infected with a temperature sensitive mutant of RSV (ts LA 29 Rat-1) can be rendered quiescent by serum deprivation at restrictive temperature. Shift to permissive conditions activates the v-src protein tyrosine kinase within 10 minutes a
Autor:
Anne W. Wyke, H. R. Perkins
Publikováno v:
Journal of General Microbiology. 88:159-168
SUMMARY: A soluble extract from Corynebacterium poinsettiae able to synthesize the nucleotide precursor of its peptidoglycan was prepared. This extract contained all the enzymes necessary for the synthesis of the peptide side-chain. The specificity o
Publikováno v:
FEMS Microbiology Letters. 10:119-122