Zobrazeno 1 - 10 of 123 pro vyhledávání: '"A W Tinsley"'
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Akademický článek
Dietary Yeast Cell Wall Extract Alters the Proteome of the Skin Mucous Barrier in Atlantic Salmon (Salmo salar): Increased Abundance and Expression of a Calreticulin-Like Protein.
Autor: Giulia Micallef, Phillip Cash, Jorge M O Fernandes, Binoy Rajan, John W Tinsley, Ralph Bickerdike, Samuel A M Martin, Alan S Bowman
Publikováno v: PLoS ONE, Vol 12, Iss 1, p e0169075 (2017)
In order to improve fish health and reduce use of chemotherapeutants in aquaculture production, the immunomodulatory effect of various nutritional ingredients has been explored. In salmon, there is evidence that functional feeds can reduce the abunda
Externí odkaz: https://doaj.org/article/13509c07197247b88a77e885b31bc50d
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Ikaros is required to survive positive selection and to maintain clonal diversity during T-cell development in the thymus
Autor: Hee-won Yoon, Megan A. Luckey, Joo-Young Park, Andrew J. Sacks, Grace Kim, Jung-Hyun Park, Kevin W. Tinsley, Lionel Feigenbaum, Changwan Hong, Hilary R. Keller
Publikováno v: Blood. 122:2358-2368
The zinc-finger protein Ikaros is a key player in T-cell development and a potent tumor suppressor in thymocytes. To understand the molecular basis of its function, we disabled Ikaros activity in vivo using a dominant negative Ikaros transgene (DN-Ik
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ec8af2176d6ced4a1f1e342b3bfdd241
https://doi.org/10.1182/blood-2012-12-472076
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Methionine-enkephalin peptides in human teeth
Autor: Chhabil Dass, Genevieve H. Fridland, Francis S. Tanzer, Peter W. Tinsley, Dominic M. Desiderio, Emirgul Tolun, John T. Killmar
Publikováno v: International Journal of Peptide and Protein Research. 32:117-122
The presence of the free opioid pentapeptide methionine enkephalin (ME) and of ME-containing peptide(s) was established firmly in decalcified, depulped human teeth by using a combination of methods including RP-HPLC, radioimmunoassay, radioreceptoras
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2aa571fbc63454b1135a9ed9e6992e7c
https://doi.org/10.1111/j.1399-3011.1988.tb00671.x
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CD4-Dependent Signaling Is Required for a Late Checkpoint during Th2 Development Associated with Resistance to Activation-Induced Cell Death
Autor: Jennifer L. Brogdon, Kevin W. Tinsley, David Leitenberg, Anahita Ramezani, Zohreh Tatari-Calderone
Publikováno v: The Journal of Immunology. 175:5629-5636
Previous studies have found that class II-restricted T cells from CD4-deficient mice reconstituted with a tail-less CD4 transgene have a specific defect in the development of Th2 effector cells; however, the reason for this defect was not clear. Foll
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b8b2283cd2fb3b4aa8875b502361bb7
https://doi.org/10.4049/jimmunol.175.9.5629
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Tissue-engineered trachea from sheep marrow stromal cells with transforming growth factor β2 released from biodegradable microspheres in a nude rat recipient
Autor: Toshihiro Kushibiki, Kevin W. Tinsley, Charles A. Vacanti, Koji Kojima, Yasuhiko Tabata, Ronald A. Ignotz
Publikováno v: The Journal of Thoracic and Cardiovascular Surgery. 128:147-153
Objective The purpose of this study was to evaluate the feasibility of using autologous sheep marrow stromal cells cultured onto polyglycolic acid mesh to develop helical engineered cartilage equivalents for a functional tracheal replacement. We also
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac22b094236ea158c3d583d5afa3557f
https://doi.org/10.1016/j.jtcvs.2004.02.038
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Sepsis Induces Apoptosis and Profound Depletion of Splenic Interdigitating and Follicular Dendritic Cells
Autor: Katherine Chang, Paul E. Swanson, Mitchell H. Grayson, Richard S. Hotchkiss, Anne M. Drewry, Kevin W. Tinsley, Irene E. Karl
Publikováno v: The Journal of Immunology. 171:909-914
Dendritic cells are a phenotypically diverse group of APC that have unique capabilities to regulate the activity and survival of B and T cells. Although proper function of dendritic cells is essential to host control of invading pathogens, few studie
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b5e3944cbdb66159bcba834fdaea437
https://doi.org/10.4049/jimmunol.171.2.909
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Adoptive transfer of apoptotic splenocytes worsens survival, whereas adoptive transfer of necrotic splenocytes improves survival in sepsis
Autor: Richard S. Hotchkiss, Kevin W. Tinsley, Irene E. Karl, Katherine Chang, Christopher G. Davis, Benjamin S. Dunne, Dale F. Osborne, Mitchell H. Grayson
Publikováno v: Proceedings of the National Academy of Sciences. 100:6724-6729
In sepsis, both necrotic and apoptotic cell death can occur. Apoptotic cells induce anergy that could impair the host response, whereas necrotic cells cause immune activation that might result in enhanced antimicrobial defenses. We determined whether
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ddac799387ab11c6add561b5627fed56
https://doi.org/10.1073/pnas.1031788100
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Role of Apoptotic Cell Death in Sepsis
Autor: Richard S. Hotchkiss, Kevin W. Tinsley, Irene E. Karl
Publikováno v: Scandinavian Journal of Infectious Diseases. 35:585-592
Sepsis is the leading cause of morbidity and mortality in critically ill patients in many intensive care units. The pathophysiology of organ failure and death in patients with sepsis remain elusive. This review focuses on recent advances in our under
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc91f5e2fe91d667a366c4d98d22e1d4
https://doi.org/10.1080/00365540310015692
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