Early life stress, low-grade systemic inflammation and weaker suppression of the default mode network (DMN) during face processing in Schizophrenia

Autor: Sinead King, David Mothersill, Laurena Holleran, Saahithh Redddi Patlola, Tom Burke, Ross McManus, Marcus Kenyon, Colm McDonald, Brian Hallahan, Aiden Corvin, Derek W. Morris, John P. Kelly, Declan P. McKernan, Gary Donohoe

Publikováno v: Translational Psychiatry, Vol 13, Iss 1, Pp 1-7 (2023)

Abstract Childhood trauma (CT) is associated with lower cognitive and social cognitive function in schizophrenia. Recent evidence suggests that the relationship between CT and cognition is mediated by both low-grade systemic inflammation and reduced

Externí odkaz: https://doaj.org/article/17c375194589468c9b8d64ca5de505dc

Grain refinement in titanium prevents low temperature oxygen embrittlement

Autor: Yan Chong, Reza Gholizadeh, Tomohito Tsuru, Ruopeng Zhang, Koji Inoue, Wenqiang Gao, Andy Godfrey, Masatoshi Mitsuhara, J. W. Morris, Andrew M. Minor, Nobuhiro Tsuji

Publikováno v: Nature Communications, Vol 14, Iss 1, Pp 1-11 (2023)

Oxygen has long been considered as a detrimental impurity in pure titanium since it can severely deteriorate the ductility. Here, the authors propose a simple, yet effective strategy via grain refinement to solve this long-standing issue, while prese

Externí odkaz: https://doaj.org/article/ef9eef807f9c45debfccd4d53d8da35c

The Atacama Cosmology Telescope: A Measurement of the DR6 CMB Lensing Power Spectrum and Its Implications for Structure Growth

Autor: Frank J. Qu, Blake D. Sherwin, Mathew S. Madhavacheril, Dongwon Han, Kevin T. Crowley, Irene Abril-Cabezas, Peter A. R. Ade, Simone Aiola, Tommy Alford, Mandana Amiri, Stefania Amodeo, Rui An, Zachary Atkins, Jason E. Austermann, Nicholas Battaglia, Elia Stefano Battistelli, James A. Beall, Rachel Bean, Benjamin Beringue, Tanay Bhandarkar, Emily Biermann, Boris Bolliet, J Richard Bond, Hongbo Cai, Erminia Calabrese, Victoria Calafut, Valentina Capalbo, Felipe Carrero, Julien Carron, Anthony Challinor, Grace E. Chesmore, Hsiao-mei Cho, Steve K. Choi, Susan E. Clark, Rodrigo Córdova Rosado, Nicholas F. Cothard, Kevin Coughlin, William Coulton, Roohi Dalal, Omar Darwish, Mark J. Devlin, Simon Dicker, Peter Doze, Cody J. Duell, Shannon M. Duff, Adriaan J. Duivenvoorden, Jo Dunkley, Rolando Dünner, Valentina Fanfani, Max Fankhanel, Gerrit Farren, Simone Ferraro, Rodrigo Freundt, Brittany Fuzia, Patricio A. Gallardo, Xavier Garrido, Vera Gluscevic, Joseph E. Golec, Yilun Guan, Mark Halpern, Ian Harrison, Matthew Hasselfield, Erin Healy, Shawn Henderson, Brandon Hensley, Carlos Hervías-Caimapo, J. Colin Hill, Gene C. Hilton, Matt Hilton, Adam D. Hincks, Renée Hložek, Shuay-Pwu Patty Ho, Zachary B. Huber, Johannes Hubmayr, Kevin M. Huffenberger, John P. Hughes, Kent Irwin, Giovanni Isopi, Hidde T. Jense, Ben Keller, Joshua Kim, Kenda Knowles, Brian J. Koopman, Arthur Kosowsky, Darby Kramer, Aleksandra Kusiak, Adrien La Posta, Alex Lague, Victoria Lakey, Eunseong Lee, Zack Li, Yaqiong Li, Michele Limon, Martine Lokken, Thibaut Louis, Marius Lungu, Niall MacCrann, Amanda MacInnis, Diego Maldonado, Felipe Maldonado, Maya Mallaby-Kay, Gabriela A. Marques, Jeff McMahon, Yogesh Mehta, Felipe Menanteau, Kavilan Moodley, Thomas W. Morris, Tony Mroczkowski, Sigurd Naess, Toshiya Namikawa, Federico Nati, Laura Newburgh, Andrina Nicola, Michael D. Niemack, Michael R. Nolta, John Orlowski-Scherer, Lyman A. Page, Shivam Pandey, Bruce Partridge, Heather Prince, Roberto Puddu, Federico Radiconi, Naomi Robertson, Felipe Rojas, Tai Sakuma, Maria Salatino, Emmanuel Schaan, Benjamin L. Schmitt, Neelima Sehgal, Shabbir Shaikh, Carlos Sierra, Jon Sievers, Cristóbal Sifón, Sara Simon, Rita Sonka, David N. Spergel, Suzanne T. Staggs, Emilie Storer, Eric R. Switzer, Niklas Tampier, Robert Thornton, Hy Trac, Jesse Treu, Carole Tucker, Joel Ullom, Leila R. Vale, Alexander Van Engelen, Jeff Van Lanen, Joshiwa van Marrewijk, Cristian Vargas, Eve M. Vavagiakis, Kasey Wagoner, Yuhan Wang, Lukas Wenzl, Edward J. Wollack, Zhilei Xu, Fernando Zago, Kaiwen Zheng

Publikováno v: The Astrophysical Journal, Vol 962, Iss 2, p 112 (2024)

We present new measurements of cosmic microwave background (CMB) lensing over 9400 deg ^2 of the sky. These lensing measurements are derived from the Atacama Cosmology Telescope (ACT) Data Release 6 (DR6) CMB data set, which consists of five seasons

Externí odkaz: https://doaj.org/article/0a0dc3b0ed0348eb991e69b7238030ba

Using brain cell-type-specific protein interactomes to interpret neurodevelopmental genetic signals in schizophrenia

Autor: Yu-Han H. Hsu, Greta Pintacuda, Ruize Liu, Eugeniu Nacu, April Kim, Kalliopi Tsafou, Natalie Petrossian, William Crotty, Jung Min Suh, Jackson Riseman, Jacqueline M. Martin, Julia C. Biagini, Daya Mena, Joshua K.T. Ching, Edyta Malolepsza, Taibo Li, Tarjinder Singh, Tian Ge, Shawn B. Egri, Benjamin Tanenbaum, Caroline R. Stanclift, Annie M. Apffel, Steven A. Carr, Monica Schenone, Jake Jaffe, Nadine Fornelos, Hailiang Huang, Kevin C. Eggan, Kasper Lage, Stephan Ripke, Benjamin M. Neale, Aiden Corvin, James T.R. Walters, Kai-How Farh, Peter A. Holmans, Phil Lee, Brendan Bulik-Sullivan, David A. Collier, Tune H. Pers, Ingrid Agartz, Esben Agerbo, Margot Albus, Madeline Alexander, Farooq Amin, Silviu A. Bacanu, Martin Begemann, Richard A. Belliveau, Jr., Judit Bene, Sarah E. Bergen, Elizabeth Bevilacqua, Tim B. Bigdeli, Donald W. Black, Richard Bruggeman, Nancy G. Buccola, Randy L. Buckner, William Byerley, Wiepke Cahn, Guiqing Cai, Dominique Campion, Rita M. Cantor, Vaughan J. Carr, Noa Carrera, Stanley V. Catts, Kimberley D. Chambert, Raymond C.K. Chan, Ronald Y.L. Chan, Eric Y.H. Chen, Wei Cheng, Eric FC. Cheung, Siow Ann Chong, C. Robert Cloninger, David Cohen, Nadine Cohen, Paul Cormican, Nick Craddock, James J. Crowley, David Curtis, Michael Davidson, Kenneth L. Davis, Franziska Degenhardt, Jurgen Del Favero, Ditte Demontis, Dimitris Dikeos, Timothy Dinan, Srdjan Djurovic, Gary Donohoe, Elodie Drapeau, Jubao Duan, Frank Dudbridge, Naser Durmishi, Peter Eichhammer, Johan Eriksson, Valentina Escott-Price, Laurent Essioux, Ayman H. Fanous, Martilias S. Farrell, Josef Frank, Lude Franke, Robert Freedman, Nelson B. Freimer, Marion Friedl, Joseph I. Friedman, Menachem Fromer, Giulio Genovese, Lyudmila Georgieva, Ina Giegling, Paola Giusti-Rodríguez, Stephanie Godard, Jacqueline I. Goldstein, Vera Golimbet, Srihari Gopal, Jacob Gratten, Lieuwe de Haan, Christian Hammer, Marian L. Hamshere, Mark Hansen, Thomas Hansen, Vahram Haroutunian, Annette M. Hartmann, Frans A. Henskens, Stefan Herms, Joel N. Hirschhorn, Per Hoffmann, Andrea Hofman, Mads V. Hollegaard, David M. Hougaard, Masashi Ikeda, Inge Joa, Antonio Julià, René S. Kahn, Luba Kalaydjieva, Sena Karachanak-Yankova, Juha Karjalainen, David Kavanagh, Matthew C. Keller, James L. Kennedy, Andrey Khrunin, Yunjung Kim, Janis Klovins, James A. Knowles, Bettina Konte, Vaidutis Kucinskas, Zita Ausrele Kucinskiene, Hana Kuzelova-Ptackova, Anna K. Kähler, Claudine Laurent, Jimmy Lee, S. Hong Lee, Sophie E. Legge, Bernard Lerer, Miaoxin Li, Tao Li, Kung-Yee Liang, Jeffrey Lieberman, Svetlana Limborska, Carmel M. Loughland, Jan Lubinski, Jouko Lönnqvist, Milan Macek, Patrik K.E. Magnusson, Brion S. Maher, Wolfgang Maier, Jacques Mallet, Sara Marsal, Manuel Mattheisen, Morten Mattingsdal, Robert W. McCarley, Colm McDonald, Andrew M. McIntosh, Sandra Meier, Carin J. Meijer, Bela Melegh, Ingrid Melle, Raquelle I. Mesholam-Gately, Andres Metspalu, Patricia T. Michie, Lili Milani, Vihra Milanova, Younes Mokrab, Derek W. Morris, Ole Mors, Kieran C. Murphy, Robin M. Murray, Inez Myin-Germeys, Bertram Müller-Myhsok, Mari Nelis, Igor Nenadic, Deborah A. Nertney, Gerald Nestadt, Kristin K. Nicodemus, Liene Nikitina-Zake, Laura Nisenbaum, Annelie Nordin, Eadbhard O'Callaghan, Colm O'Dushlaine, F. Anthony O'Neill, Sang-Yun Oh, Ann Olincy, Line Olsen, Jim Van Os, Christos Pantelis, George N. Papadimitriou, Sergi Papiol, Elena Parkhomenko, Michele T. Pato, Tiina Paunio, Milica Pejovic-Milovancevic, Diana O. Perkins, Olli Pietiläinen, Jonathan Pimm, Andrew J. Pocklington, John Powell, Alkes Price, Ann E. Pulver, Shaun M. Purcell, Digby Quested, Henrik B. Rasmussen, Abraham Reichenberg, Mark A. Reimers, Alexander L. Richards, Joshua L. Roffman, Panos Roussos, Douglas M. Ruderfer, Veikko Salomaa, Alan R. Sanders, Ulrich Schall, Christian R. Schubert, Thomas G. Schulze, Sibylle G. Schwab, Edward M. Scolnick, Rodney J. Scott, Larry J. Seidman, Jianxin Shi, Engilbert Sigurdsson, Teimuraz Silagadze, Jeremy M. Silverman, Kang Sim, Petr Slominsky, Jordan W. Smoller, Hon-Cheong So, Chris C.A. Spencer, Eli A. Stahl, Hreinn Stefansson, Stacy Steinberg, Elisabeth Stogmann, Richard E. Straub, Eric Strengman, Jana Strohmaier, T Scott Stroup, Mythily Subramaniam, Jaana Suvisaari, Dragan M. Svrakic, Jin P. Szatkiewicz, Erik Söderman, Srinivas Thirumalai, Draga Toncheva, Sarah Tosato, Juha Veijola, John Waddington, Dermot Walsh, Dai Wang, Qiang Wang, Bradley T. Webb, Mark Weiser, Dieter B. Wildenauer, Nigel M. Williams, Stephanie Williams, Stephanie H. Witt, Aaron R. Wolen, Emily H.M. Wong, Brandon K. Wormley, Hualin Simon Xi, Clement C. Zai, Xuebin Zheng, Fritz Zimprich, Naomi R. Wray, Kari Stefansson, Peter M. Visscher, Rolf Adolfsson, Ole A. Andreassen, Douglas H.R. Blackwood, Elvira Bramon, Joseph D. Buxbaum, Anders D. Børglum, Sven Cichon, Ariel Darvasi, Enrico Domenici, Hannelore Ehrenreich, Tõnu Esko, Pablo V. Gejman, Michael Gill, Hugh Gurling, Christina M. Hultman, Nakao Iwata, Assen V. Jablensky, Erik G. Jönsson, Kenneth S. Kendler, George Kirov, Jo Knight, Todd Lencz, Douglas F. Levinson, Qingqin S. Li, Jianjun Liu, Anil K. Malhotra, Steven A. McCarroll, Andrew McQuillin, Jennifer L. Moran, Preben B. Mortensen, Bryan J. Mowry, Markus M. Nöthen, Roel A. Ophoff, Michael J. Owen, Aarno Palotie, Carlos N. Pato, Tracey L. Petryshen, Danielle Posthuma, Marcella Rietschel, Brien P. Riley, Dan Rujescu, Pak C. Sham, Pamela Sklar, David St Clair, Daniel R. Weinberger, Jens R. Wendland, Thomas Werge, Mark J. Daly, Patrick F. Sullivan, Michael C. O'Donovan, Shengying Qin, Akira Sawa, Rene Kahn, Kyung Sue Hong, Wenzhao Shi, Ming Tsuang, Masanari Itokawa, Gang Feng, Stephen J. Glatt, Xiancang Ma, Jinsong Tang, Yunfeng Ruan, Feng Zhu, Yasue Horiuchi, Byung Dae Lee, Eun-Jeong Joo, Woojae Myung, Kyooseob Ha, Hong-Hee Won, Ji Hyung Baek, Young Chul Chung, Sung-Wan Kim, Agung Kusumawardhani, Wei J. Chen, Hai-Gwo Hwu, Akitoyo Hishimoto, Ikuo Otsuka, Ichiro Sora, Tomoko Toyota, Takeo Yoshikawa, Hiroshi Kunugi, Kotaro Hattori, Sayuri Ishiwata, Shusuke Numata, Tetsuro Ohmori, Makoto Arai, Yuji Ozeki, Kumiko Fujii, Se Joo Kim, Heon-Jeong Lee, Yong Min Ahn, Se Hyun Kim, Kazufumi Akiyama, Kazutaka Shimoda, Makoto Kinoshita

Publikováno v: iScience, Vol 26, Iss 5, Pp 106701- (2023)

Summary: Genetics have nominated many schizophrenia risk genes and identified convergent signals between schizophrenia and neurodevelopmental disorders. However, functional interpretation of the nominated genes in the relevant brain cell types is oft

Externí odkaz: https://doaj.org/article/49cc77d8d4ee4572b1f6ef76532d303e

Influence of infrastructure, ecology, and underpass-dimensions on multi-year use of Standard Gauge Railway underpasses by mammals in Tsavo, Kenya

Autor: Fredrick Lala, Patrick I. Chiyo, Patrick Omondi, Benson Okita-Ouma, Erustus Kanga, Michael Koskei, Lydia Tiller, Aaron W. Morris, William J. Severud, Joseph K. Bump

Publikováno v: Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)

Abstract Rail and road infrastructure is essential for economic growth and development but can cause a gradual loss in biodiversity and degradation of ecosystem function and services. We assessed the influence of underpass dimensions, fencing, proxim

Externí odkaz: https://doaj.org/article/9c1c471c953d42af92ef3d42e710e725