Zobrazeno 1 - 10
of 4 714
pro vyhledávání: '"A W Gray"'
Autor:
Kira M. Hoffman, Kelsey Copes-Gerbitz, Sarah Dickson-Hoyle, Mathieu Bourbonnais, Jodi Axelson, Amy Cardinal Christianson, Lori D. Daniels, Robert W. Gray, Peter Holub, Nicholas Mauro, Dinyar Minocher, Dave Pascal
Publikováno v:
FACETS, Vol 9, Iss , Pp 1-11 (2024)
Western Canada is increasingly experiencing impactful and complex wildfire seasons. In response, there are urgent calls to implement prescribed and cultural fire as a key solution to this complex challenge. Unfortunately, there has been limited inves
Externí odkaz:
https://doaj.org/article/f9992d71a8314ee6aff49c3559b7c0dd
Autor:
Zinab O. Doha, Xiaoyan Wang, Nicholas L. Calistri, Jennifer Eng, Colin J. Daniel, Luke Ternes, Eun Na Kim, Carl Pelz, Michael Munks, Courtney Betts, Sunjong Kwon, Elmar Bucher, Xi Li, Trent Waugh, Zuzana Tatarova, Dylan Blumberg, Aaron Ko, Nell Kirchberger, Jennifer A. Pietenpol, Melinda E. Sanders, Ellen M. Langer, Mu-Shui Dai, Gordon Mills, Koei Chin, Young Hwan Chang, Lisa M. Coussens, Joe W. Gray, Laura M. Heiser, Rosalie C. Sears
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-21 (2023)
Abstract Triple-negative breast cancer (TNBC) patients have a poor prognosis and few treatment options. Mouse models of TNBC are important for development of new therapies, however, few mouse models represent the complexity of TNBC. Here, we develop
Externí odkaz:
https://doaj.org/article/2f5efa1be7d149bcb492c236e0e02ed5
Autor:
Marc-André Parisien, Quinn E. Barber, Mathieu L. Bourbonnais, Lori D. Daniels, Mike D. Flannigan, Robert W. Gray, Kira M. Hoffman, Piyush Jain, Scott L. Stephens, Steve W. Taylor, Ellen Whitman
Publikováno v:
Communications Earth & Environment, Vol 4, Iss 1, Pp 1-11 (2023)
Abstract In the province of British Columbia, Canada, four of the most severe wildfire seasons of the last century occurred in the past 7 years: 2017, 2018, 2021, and 2023. To investigate trends in wildfire activity and fire-conducive climate, we con
Externí odkaz:
https://doaj.org/article/46d83568643946b9a3138a881930154a
Autor:
Maikel Izquierdo, De Lin, Sandra O'Neill, Lauren A Webster, Christy Paterson, John Thomas, Mirtha Elisa Aguado, Enrique Colina Araújo, Daniel Alpízar-Pedraza, Halimatu Joji, Lorna MacLean, Anthony Hope, David W Gray, Martin Zoltner, Mark C Field, Jorge González-Bacerio, Manu De Rycker
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 18, Iss 2, p e0011956 (2024)
BackgroundChagas disease is caused by the protozoan parasite Trypanosoma cruzi and leads to ~10,000 deaths each year. Nifurtimox and benznidazole are the only two drugs available but have significant adverse effects and limited efficacy. New chemothe
Externí odkaz:
https://doaj.org/article/eda16b548238447697b8e6f336b5e1ca
Design of the Global Health chemical diversity library v2 for screening against infectious diseases.
Autor:
Caroline Wilson, J Mark F Gardner, David W Gray, Beatriz Baragana, Paul G Wyatt, Alex Cookson, Stephen Thompson, Cesar Mendoza-Martinez, Michael J Bodkin, Ian H Gilbert, Gary J Tarver
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 17, Iss 12, p e0011799 (2023)
There is a need for novel chemical matter for phenotypic and target-based screens to find starting points for drug discovery programmes in neglected infectious diseases and non-hormonal contraceptives that disproportionately affect Low- and Middle-In
Externí odkaz:
https://doaj.org/article/ae7dc23b661c42e4b35f3b3a4b1a1f7f
Autor:
Lucas Pagano, Guillaume Thibault, Walid Bousselham, Jessica L. Riesterer, Xubo Song, Joe W. Gray
Publikováno v:
Frontiers in Bioinformatics, Vol 3 (2023)
Electron microscopy (EM) enables imaging at a resolution of nanometers and can shed light on how cancer evolves to develop resistance to therapy. Acquiring these images has become a routine task.However, analyzing them is now a bottleneck, as manual
Externí odkaz:
https://doaj.org/article/475cacb7b29c4ee498b9be62b982df58
Autor:
Archana Machireddy, Guillaume Thibault, Kevin G. Loftis, Kevin Stoltz, Cecilia E. Bueno, Hannah R. Smith, Jessica L. Riesterer, Joe W. Gray, Xubo Song
Publikováno v:
Frontiers in Bioinformatics, Vol 3 (2023)
Focused ion beam-scanning electron microscopy (FIB-SEM) images can provide a detailed view of the cellular ultrastructure of tumor cells. A deeper understanding of their organization and interactions can shed light on cancer mechanisms and progressio
Externí odkaz:
https://doaj.org/article/bc3ae797726a4f60909e38b700bc6248
Autor:
Matus Valach, Sandrine Moreira, Celine Petitjean, Corinna Benz, Anzhelika Butenko, Olga Flegontova, Anna Nenarokova, Galina Prokopchuk, Tom Batstone, Pascal Lapébie, Lionnel Lemogo, Matt Sarrasin, Paul Stretenowich, Pragya Tripathi, Euki Yazaki, Takeshi Nara, Bernard Henrissat, B. Franz Lang, Michael W. Gray, Tom A. Williams, Julius Lukeš, Gertraud Burger
Publikováno v:
BMC Biology, Vol 21, Iss 1, Pp 1-17 (2023)
Abstract Background Diplonemid flagellates are among the most abundant and species-rich of known marine microeukaryotes, colonizing all habitats, depths, and geographic regions of the world ocean. However, little is known about their genomes, biology
Externí odkaz:
https://doaj.org/article/d52b66df69fd49b39786a1f81803704a
Autor:
Erik Burlingame, Luke Ternes, Jia-Ren Lin, Yu-An Chen, Eun Na Kim, Joe W. Gray, Young Hwan Chang
Publikováno v:
Frontiers in Bioinformatics, Vol 3 (2023)
Introduction: Tissue-based sampling and diagnosis are defined as the extraction of information from certain limited spaces and its diagnostic significance of a certain object. Pathologists deal with issues related to tumor heterogeneity since analyzi
Externí odkaz:
https://doaj.org/article/60189829c99e49eba6f2198e25d9a4ac
Publikováno v:
Production and Manufacturing Research: An Open Access Journal, Vol 10, Iss 1, Pp 294-320 (2022)
Management of variability in raw materials is critical in food manufacturing systems, where the variability of input attributes is a result of its biological nature. We present a methodology for the analysis of such production systems that provides a
Externí odkaz:
https://doaj.org/article/e7d9b6c849f949859e5ef1e2a228a9d4