Zobrazeno 1 - 10
of 784
pro vyhledávání: '"A W, Welsh"'
Autor:
Justine W. Welsh, Rebecca M. Durham, Siara I. Sitar, Kathryn C. Modisette, Barbara D. Estrada, Michael L. Dennis
Publikováno v:
Psychiatric Research and Clinical Practice, Vol 6, Iss 4, Pp 143-150 (2024)
Objective Early identification of substance use during adolescence is imperative to reduce the risk of morbidity and mortality. The aim of this study was to determine the utility of the Global Appraisal of Individual Needs‐Quick Version 4 (GAIN‐Q
Externí odkaz:
https://doaj.org/article/028b3d8830034e328fb31d20cc4ff47e
Autor:
Yun Hu, Sébastien Paris, Narayan Sahoo, Qi Wang, Qianxia Wang, Hampartsoum B. Barsoumian, Ailing Huang, Jordan Da Silva, Célia Bienassis, Claudia S. Kettlun Leyton, Tiffany A. Voss, Fatemeh Masrorpour, Thomas Riad, Carola Leuschner, Nahum Puebla-Osorio, Saumil Gandhi, Quynh-Nhu Nguyen, Jing Wang, Maria Angelica Cortez, James W. Welsh
Publikováno v:
Journal of Nanobiotechnology, Vol 22, Iss 1, Pp 1-22 (2024)
Abstract Recent findings suggest that immunoradiotherapy (IRT), combining photon radiotherapy (XRT) or proton radiotherapy (PRT) with immune checkpoint blockade, can enhance systemic tumor control. However, the comparative efficacy of XRT and PRT in
Externí odkaz:
https://doaj.org/article/3c08becd51c4497faf642983fc0d91a9
Autor:
Kewen He, Nahum Puebla-Osorio, Hampartsoum B. Barsoumian, Duygu Sezen, Zahid Rafiq, Thomas S. Riad, Yun Hu, Ailing Huang, Tiffany A. Voss, Claudia S. Kettlun Leyton, Lily Jae Schuda, Ethan Hsu, Joshua Heiber, Maria-Angelica Cortez, James W. Welsh
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-14 (2024)
Abstract Background Combining interleukin-2 (IL-2) with radiotherapy (RT) and immune checkpoint blockade (ICB) has emerged as a promising approach to address ICB resistance. However, conventional IL-2 cytokine therapy faces constraints owing to its b
Externí odkaz:
https://doaj.org/article/d5dfdad3aeaf4ef7a03ae6638ec04617
Autor:
Joseph D. Butner, Prashant Dogra, Caroline Chung, Eugene J. Koay, James W. Welsh, David S. Hong, Vittorio Cristini, Zhihui Wang
Publikováno v:
npj Systems Biology and Applications, Vol 10, Iss 1, Pp 1-14 (2024)
Abstract We present a study where predictive mechanistic modeling is combined with deep learning methods to predict individual patient survival probabilities under immune checkpoint inhibitor (ICI) immunotherapy. This hybrid approach enables predicti
Externí odkaz:
https://doaj.org/article/ec3e14cd43a442aab424aba4348ea914
Autor:
Nahum Puebla-Osorio, Natalie Wall Fowlkes, Hampartsoum B. Barsoumian, Kristina Xega, Gitika Srivastava, Claudia Kettlun-Leyton, Sara Nizzero, Tiffany Voss, Thomas S. Riad, Christina Wong, Ailing Huang, Yun Hu, Joylise Mitchell, Mingee Kim, Zahid Rafiq, Kewen He, Duygu Sezen, Ethan Hsu, Fatemeh Masrorpour, Aurian Maleki, Carola Leuschner, Maria Angelica Cortez, Philipp Oertle, Marko Loparic, Marija Plodinec, Janet L. Markman, James W. Welsh
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
IntroductionEffective infiltration of chimeric antigen receptor T (CAR-T) cells into solid tumors is critical for achieving a robust antitumor response and improving therapeutic outcomes. While CAR-T cell therapies have succeeded in hematologic malig
Externí odkaz:
https://doaj.org/article/e15d8e28463245d5a2e2e3d70c939f5b
Autor:
Yun Hu, Alexey Revenko, Hampartsoum Barsoumian, Genevieve Bertolet, Natalie Wall Fowlkes, Hadi Maazi, Morgan Maureen Green, Kewen He, Duygu Sezen, Tiffany A. Voss, Claudia S Kettlun Leyton, Fatemeh Masrorpour, Zahid Rafiq, Nahum Puebla-Osorio, Carola Leuschner, Robert MacLeod, Maria Angelica Cortez, James W. Welsh
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-15 (2024)
Abstract Background The combination of radiotherapy and immunotherapy (immunoradiotherapy) has been increasingly used for treating a wide range of cancers. However, some tumors are resistant to immunoradiotherapy. We have previously shown that MER pr
Externí odkaz:
https://doaj.org/article/bfe32f32799d4d64804e7e64eb090fe4
Autor:
Cecilia A. Hinojosa , PhD, Siara I. Sitar , MS, Joshua C. Zhao , BS, Joshua D. Barbosa , MD, Denise A. Hien , PhD, ABPP, Justine W. Welsh , MD, Negar Fani , PhD, Sanne J.H. van Rooij , PhD
Publikováno v:
Chronic Stress, Vol 8 (2024)
Substance use disorder (SUD) is a significant health problem, and trauma exposure is a known risk factor for the escalation of substance use. However, the shared neural mechanisms through which trauma is associated with substance use are still unknow
Externí odkaz:
https://doaj.org/article/3a21842e155d48c88fe37c507efb5a34
Autor:
Kewen He, Nahum Puebla-Osorio, Hampartsoum B. Barsoumian, Duygu Sezen, Zahid Rafq, Thomas S. Riad, Yun Hu, Ailing Huang, Tifany A. Voss, Claudia S. Kettlun Leyton, Lily Jae Schuda, Ethan Hsu, Joshua Heiber, Maria-Angelica Cortez, James W. Welsh
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/6dc555a438aa4754a8956da5b8b452ea
Autor:
Justine W Welsh, Siara I Sitar, Michael J Parks, Samantha C Patton, Jacqueline E Braughton, Lance A Waller, Quyen M Ngo
Publikováno v:
JMIR Human Factors, Vol 10, p e48701 (2023)
BackgroundThe use of virtual treatment services increased dramatically during the COVID-19 pandemic. Unfortunately, large-scale research on virtual treatment for substance use disorder (SUD), including factors that may influence outcomes, has not adv
Externí odkaz:
https://doaj.org/article/53e1177cf9804006a391edffc341b91b
Autor:
Hampartsoum B. Barsoumian, Jerry Hsu, Selene Nanez, Yun Hu, Ethan Y. Hsu, Thomas S. Riad, Nahum Puebla-Osorio, Maria Angelica Cortez, James W. Welsh
Publikováno v:
Immuno, Vol 3, Iss 1, Pp 74-85 (2023)
Since the momentous discovery of X-rays, high-dose radiotherapy (H-XRT) has been a cornerstone for combating cancer. The high-energy electromagnetic waves induce direct damage to tumor-cells’ DNA, thereby halting cell growth and proliferation, and
Externí odkaz:
https://doaj.org/article/d82617074f4e4d829e76cb19dd1dd2bf