Zobrazeno 1 - 10
of 20
pro vyhledávání: '"A W, Teass"'
Autor:
Dale W. Porter, Jeffery McLaurin, Kurt Brumbaugh, Vincent Castranova, Christoper M. Beighley, Lyndell Millecchia, Alexander W. Teass, Dawn Ramsey, Amir Khan, Victor A. Robinson, Patsy Willard
Publikováno v:
Toxicological Sciences. 90:188-197
Our laboratory has previously reported results from a rat silica inhalation study which determined that, even after silica exposure ended, pulmonary inflammation and damage progressed with subsequent fibrosis development. In the present study, the re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53ecd7258e6c58172463fff29d5f2065
https://doi.org/10.1093/toxsci/kfj075
https://doi.org/10.1093/toxsci/kfj075
Autor:
Dawn Ramsey, Kurt Brumbaugh, Vincent Castranova, Lori A. Battelli, Victor A. Robinson, Amir Khan, Alexander W. Teass, Ann F. Hubbs, Dale W. Porter, Robert R. Mercer, Jeff McLaurin
Publikováno v:
Toxicological Sciences. 79:370-380
Human epidemiologic studies have found that silicosis may develop or progress even after occupational exposure has ended, suggesting that there is a threshold lung burden above which silica-induced pulmonary disease progresses without further exposur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1724eeefa3bdc4aae44dcf32761ba61a
https://doi.org/10.1093/toxsci/kfh110
https://doi.org/10.1093/toxsci/kfh110
Autor:
Jeff McLaurin, Victor A. Robinson, Alexander W. Teass, Douglas Landsittel, Patsy Willard, Donna Pack, Dawn Ramsey, Ann F. Hubbs, Dale W. Porter, Lyndell Millecchia, Vincent Castranova, Amir Khan
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 283:L485-L493
In previous reports from this study, measurements of pulmonary inflammation, bronchoalveolar lavage cell cytokine production and nuclear factor-κB activation, cytotoxic damage, and fibrosis were detailed. In this study, we investigated the temporal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87aab098fea57c368f8cbe8141d63cb2
https://doi.org/10.1152/ajplung.00427.2001
https://doi.org/10.1152/ajplung.00427.2001
Autor:
Vincent Castranova, Mark Barger, Amir Khan, Jane Ma, Dale W. Porter, Jeff McLaurin, Dawn Ramsey, Douglas Landsittel, Jianping Ye, Alexander W. Teass, Victor A. Robinson
Publikováno v:
Inhalation Toxicology. 14:349-367
In vitro studies suggest that silica-induced lung disease may be linked to processes regulated by nuclear factor-kappa B (NF-kappa B) activation, but this has not been examined in vivo. Rats were exposed to a silica aerosol of 15 mg/m(3) (6 h/day, 5
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37fae4b68e45cbdbceb90a8d1e13a489
https://doi.org/10.1080/08958370252870998
https://doi.org/10.1080/08958370252870998
Autor:
Val Vallyathan, Donna Pack, Vincent Castranova, Mark Barger, Dawn Ramsey, Steven S. Leonard, Jane Y. C. Ma, Jeffrey L. McLaurin, Alex W. Teass, Nar S. Dalal
Publikováno v:
Environmental Health Perspectives
Fracturing quartz produces silica-based radicals on the fracture planes and generates hydroxyl radicals (.OH) in aqueous media. .OH production has been shown to be directly associated with quartz-induced cell damage and phagocyte activation in vitro.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d0edc79a0490e378cc1d17e91d8a4e2
https://doi.org/10.1289/ehp.97105s51319
https://doi.org/10.1289/ehp.97105s51319
Autor:
Gabriele Sabbioni, D. Gayle DeBord, Kenneth K. Brown, Avima M. Ruder, Robert P. Streicher, Dennis R. Roberts, Elizabeth M. Ward, Alexander W. Teass, Glenn Talaska
Publikováno v:
JNCI Journal of the National Cancer Institute. 88:1046-1053
Background: In April 1991, an excess of bladder cancer cases among workers employed at a chemical manufacturing facility in Niagara Falls, NY, was reported. This excess was primarily confined to 708 workers who had ever been employed in the rubber ch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e80b666b0dfeb4e41337d39261ca2ed
https://doi.org/10.1093/jnci/88.15.1046
https://doi.org/10.1093/jnci/88.15.1046
Autor:
Dawn Ramsey, Jean Xiang, Dale A. Shoemaker, Nar S. Dalai, Linda Bowman, Alex W. Teass, Jack Blackford, Diane Schwegler-Berry, Jeff McLaurin, Paul A. Baron, Vincent Castranova, Donna Pack, Ann F. Hubbs, Kenneth C. Weber, Mark Barger, Amir Khan, Charles P. Childress, Jane Y. C. Ma, Val Vallyathan, Jack R. Pretty, Lloyd E. Stettler, William H. Pailes, Philip R. Miles, Richard D. Dey
Publikováno v:
Applied Occupational and Environmental Hygiene. 11:937-941
We have reported previously that grinding crystalline silica generates radicals on its cleavage planes and that this fresh dust is more cytotoxic in vitro than aged silica. The objective of the present study was to determine if freshly fractured sili
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::259e87c699a8f8c733b6ad953e0ac701
https://doi.org/10.1080/1047322x.1996.10389993
https://doi.org/10.1080/1047322x.1996.10389993
Publikováno v:
Applied Occupational and Environmental Hygiene. 10:557-565
A urinalysis method for o-toluidine and aniline was developed for biological monitoring. Urine specimens were made 4.7 M in sodium hydroxide and heated at 80°C for 2 hours to convert the metabolites acetanilide and N-acetyl-o-toluidine to the free a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::57f70e95065313dc9bd3ecd603fbd515
https://doi.org/10.1080/1047322x.1995.10389074
https://doi.org/10.1080/1047322x.1995.10389074
Publikováno v:
Applied Occupational and Environmental Hygiene. 7:231-240
A method for the estimation of formaldehyde dose from inhalable dust/fibers using a commercially available inhalable sampler was developed. Filters containing sampled dust/fibers were placed in 10 ml of distilled water and incubated at 37°C for 4 ho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a98993e5199747b13c354fe9ff83df16
https://doi.org/10.1080/1047322x.1992.10389766
https://doi.org/10.1080/1047322x.1992.10389766
Autor:
Vincent Castranova, Lyndell Millecchia, Alexander W. Teass, Jane Y. C. Ma, Ann F. Hubbs, Dale W. Porter
Publikováno v:
Oxygen/Nitrogen Radicals: Cell Injury and Disease ISBN: 9781461353881
Numerous investigations have been conducted to elucidate mechanisms involved in the initiation and progression of silicosis. However, most of these studies involved bolus exposure of rats to silica, i.e. intratracheal instillation or a short duration
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::90370e86df206be265984347286a67d2
https://doi.org/10.1007/978-1-4615-1087-1_20
https://doi.org/10.1007/978-1-4615-1087-1_20
