Zobrazeno 1 - 10
of 312
pro vyhledávání: '"A W, Tank"'
Autor:
Zhihao Zheng, Christopher S. Own, Adrian A. Wanner, Randal A. Koene, Eric W. Hammerschmith, William M. Silversmith, Nico Kemnitz, Ran Lu, David W. Tank, H. Sebastian Seung
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-11 (2024)
Abstract Serial section transmission electron microscopy (TEM) has proven to be one of the leading methods for millimeter-scale 3D imaging of brain tissues at nanoscale resolution. It is important to further improve imaging efficiency to acquire larg
Externí odkaz:
https://doaj.org/article/cd50b5dc025f445b9fa3853971c5a1c2
Autor:
P. Dylan Rich, Stephan Yves Thiberge, Benjamin B. Scott, Caiying Guo, D. Gowanlock R. Tervo, Carlos D. Brody, Alla Y. Karpova, Nathaniel D. Daw, David W. Tank
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract The precise neural mechanisms within the brain that contribute to the remarkable lifetime persistence of memory are not fully understood. Two-photon calcium imaging allows the activity of individual cells to be followed across long periods,
Externí odkaz:
https://doaj.org/article/d3f4113102e34dc08850517228dca327
Autor:
Lucas Pinto, Sue A. Koay, Ben Engelhard, Alice M. Yoon, Ben Deverett, Stephan Y. Thiberge, Ilana B. Witten, David W. Tank, Carlos D. Brody
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 16 (2022)
Externí odkaz:
https://doaj.org/article/3b79c2c3a0f04ffe9dd44f71daaa528e
Autor:
Sebastian Ströh, Eric W Hammerschmith, David W Tank, H Sebastian Seung, Adrian Andreas Wanner
Publikováno v:
eLife, Vol 11 (2022)
Electron microscopy of biological tissue has recently seen an unprecedented increase in imaging throughput moving the ultrastructural analysis of large tissue blocks such as whole brains into the realm of the feasible. However, homogeneous, high-qual
Externí odkaz:
https://doaj.org/article/fff3a7819e294d4badc95eca7958c24c
Publikováno v:
eLife, Vol 11 (2022)
Cortical areas seem to form a hierarchy of intrinsic timescales, but the relevance of this organization for cognitive behavior remains unknown. In particular, decisions requiring the gradual accrual of sensory evidence over time recruit widespread ar
Externí odkaz:
https://doaj.org/article/0a7c2f5766d142c7ac008d8afb9e09a8
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-7 (2019)
Disruption of cerebellar activity impairs working memory during evidence accumulation in mice. Here, the authors show that optogenetic perturbation of Purkinje cell activity disrupts the accurate accumulation of somatosensory information in working m
Externí odkaz:
https://doaj.org/article/de6e44beedb043dfbf9f02ffc63f0b8e
Publikováno v:
eLife, Vol 9 (2020)
How does the brain internally represent a sequence of sensory information that jointly drives a decision-making behavior? Studies of perceptual decision-making have often assumed that sensory cortices provide noisy but otherwise veridical sensory inp
Externí odkaz:
https://doaj.org/article/ab83e300f1414736bc8c16516b6839a6
Publikováno v:
eLife, Vol 9 (2020)
During spatial navigation, animals use self-motion to estimate positions through path integration. However, estimation errors accumulate over time and it is unclear how they are corrected. Here we report a new cell class (‘cue cell’) encoding vis
Externí odkaz:
https://doaj.org/article/55ba272338e3470d9a6e5f91e8dd61ee
Publikováno v:
J Physiol
A fundamental principle of biological motor control is that the neural commands driving movement must conform to the response properties of the motor plants they control. In the oculomotor system, characterizations of oculomotor plant dynamics tradit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::926011f4118d37648ad936bb56486f93
https://doi.org/10.1113/jp282496
https://doi.org/10.1113/jp282496
Autor:
Andrea Giovannucci, Johannes Friedrich, Pat Gunn, Jérémie Kalfon, Brandon L Brown, Sue Ann Koay, Jiannis Taxidis, Farzaneh Najafi, Jeffrey L Gauthier, Pengcheng Zhou, Baljit S Khakh, David W Tank, Dmitri B Chklovskii, Eftychios A Pnevmatikakis
Publikováno v:
eLife, Vol 8 (2019)
Advances in fluorescence microscopy enable monitoring larger brain areas in-vivo with finer time resolution. The resulting data rates require reproducible analysis pipelines that are reliable, fully automated, and scalable to datasets generated over
Externí odkaz:
https://doaj.org/article/d7b31fa323ac445a92728f820909d1e0