Zobrazeno 1 - 10
of 17
pro vyhledávání: '"A W, Siadak"'
Autor:
Russell J. Sanderson, Michelle A. Hering, Stephanie F. James, Michael M.C. Sun, Svetlana O. Doronina, Anthony W. Siadak, Peter D. Senter, Alan F. Wahl
Publikováno v:
Clinical Cancer Research. 11:843-852
Effective antibody-drug conjugates (ADC) combine high drug-linker stability in circulation and efficient intratumoral release of drug. Conjugation of monomethyl auristatin E (MMAE) to the anti-CD30 monoclonal antibody (mAb), cAC10, produced a selecti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bec13f19ba43e444582eba88f397050f
https://doi.org/10.1158/1078-0432.843.11.2
https://doi.org/10.1158/1078-0432.843.11.2
Autor:
Juliet G. Carbon, Mariya T. Sweetwyne, Rolf A. Brekken, E. Helene Sage, Amy D. Bradshaw, Carrie Murri, Anthony W. Siadak, Gail Workman
Publikováno v:
Journal of Histochemistry & Cytochemistry. 52:723-733
SPARC (osteonectin, BM-40) is a matricellular glycoprotein that is expressed in many embryogenic and adult tissues undergoing remodeling or repair. SPARC modulates cellular interaction with the extracellular matrix (ECM), inhibits cell adhesion and p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0172d8b2582507d36ac2ad83201e6e40
https://doi.org/10.1369/jhc.3a6153.2004
https://doi.org/10.1369/jhc.3a6153.2004
Autor:
Lucas C. Armstrong, Kurt D. Hankenson, Charlotte E. Stiles, Anthony W. Siadak, Benny Björkblom, Paul Bornstein
Publikováno v:
Molecular Biology of the Cell
The matricellular protein thrombospondin 2 (TSP2) regulates a variety of cell–matrix interactions. A prominent feature of TSP2-null mice is increased microvascular density, particularly in connective tissues synthesized after injury. We investigate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f74a9a791ec6e51491b98206992d3e4
https://doi.org/10.1091/mbc.e01-09-0066
https://doi.org/10.1091/mbc.e01-09-0066
Autor:
Russell J, Sanderson, Michelle A, Hering, Stephanie F, James, Michael M C, Sun, Svetlana O, Doronina, Anthony W, Siadak, Peter D, Senter, Alan F, Wahl
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 11(2 Pt 1)
Effective antibody-drug conjugates (ADC) combine high drug-linker stability in circulation and efficient intratumoral release of drug. Conjugation of monomethyl auristatin E (MMAE) to the anti-CD30 monoclonal antibody (mAb), cAC10, produced a selecti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2e2feb729bdaaeea268c5151afd69276
https://pubmed.ncbi.nlm.nih.gov/15701875
https://pubmed.ncbi.nlm.nih.gov/15701875
Autor:
E. Helene Sage, Rolf A. Brekken, Anthony W. Siadak, Amy D. Bradshaw, Paul E. Framson, Juliet G. Carbon, Carrie Murri, Millicent M. Sullivan, Gail Workman
Publikováno v:
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society. 52(6)
Hevin, also known as SC1, MAST 9, SPARC-like 1, RAGS1 and ECM2, is a member of the SPARC-related family of matricellular proteins. Mouse hevin is 53% identical to mouse SPARC, and both proteins share a follistatin-like module and an extracellular Ca2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2105f882e184d1fb1f074f50ad0516a8
https://pubmed.ncbi.nlm.nih.gov/15150282
https://pubmed.ncbi.nlm.nih.gov/15150282
Publikováno v:
Biochemistry. 36(9)
CD6 is a member of the scavenger receptor cysteine rich protein superfamily (SRCRSF). This family includes many cell surface proteins whose three-dimensional structures and functions are presently not well understood. The extracellular region of CD6
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::404149e323094f7f8e24645a0be15aef
https://pubmed.ncbi.nlm.nih.gov/9054570
https://pubmed.ncbi.nlm.nih.gov/9054570
Autor:
J A, Ledbetter, J A, Francisco, C B, Siegall, L K, Gilliland, D, Hollenbaugh, A, Aruffo, A W, Siadak, N, Mischel-Petty, L S, Grosmaire, M L, Gordon, T J, Brown, P, Moran-Davis, R S, Mittler, P A, Kiener, S G, Nadler
Publikováno v:
Critical reviews in immunology. 17(5-6)
A single-chain Fv (sFv) was expressed from the variable regions of the CD40-specific mAb G28-5. The molecule bound CD40 with a high affinity (2.2 nM) and was a monomer in solution. Surprisingly, G28-5 sFv was a potent CD40 agonist that rapidly crossl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::171a70b06a698b40ba223ec40c0805fd
https://pubmed.ncbi.nlm.nih.gov/9419430
https://pubmed.ncbi.nlm.nih.gov/9419430
Two murine monoclonal antibodies, IIG5 (IgG3) and IVE8 (IgG2a), that bind to Pseudomonas aeruginosa type a flagella and type b flagella, respectively, were prepared by conventional hybridoma methodology. Specificity of each monoclonal antibody for ty
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d428fc3517a7d4415339107ccca8f57
https://europepmc.org/articles/PMC313741/
https://europepmc.org/articles/PMC313741/
Publikováno v:
The Journal of Immunology. 127:1920-1923
We have undertaken a direct comparison of 8 different murine monoclonal antibodies that recognize antigens shared by human T cells and certain malignant B cells. Immune precipitation, lysostripping, and competitive binding experiments indicate that t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6c149a0558d043e3eab0e70b8a5898d2
https://doi.org/10.4049/jimmunol.127.5.1920
https://doi.org/10.4049/jimmunol.127.5.1920