Zobrazeno 1 - 10
of 223
pro vyhledávání: '"A W, O'Reilly"'
Autor:
Deirdre Green, Kate Richards, Brendan Doyle, Chris Thompson, Arnold Hill, Michael W O’Reilly, Mark Sherlock
Publikováno v:
Endocrinology, Diabetes & Metabolism Case Reports, Vol 1, Iss 1, Pp 1-5 (2024)
Adrenocortical carcinoma (ACC) is a rare malignant tumour arising from the adrenal cortex, with an estimated annual incidence of one to two patients per million. Ectopic ACCs are extremely rare. The majority of ACCs are sporadic; however, ACC has bee
Externí odkaz:
https://doaj.org/article/1772afb154a3463e9a8f91c46f7280ab
Publikováno v:
Endocrine Connections, Vol 13, Iss 2, Pp 1-15 (2024)
Despite the availability of adrenal hormone replacement therapy, patients with adrenal insufficiency can be affected by reduced fertility and parity. Patients with well-managed adrenal insufficiency are expected to have uneventful pregnancies and fav
Externí odkaz:
https://doaj.org/article/20d4f45dd5d245ac98b9ff623dc3afd9
Autor:
Mirna Elghobashy, Gar Mun Lau, Meri Davitadze, Caroline D. T. Gillett, Michael W. O’Reilly, Wiebke Arlt, PCOS SEva Working Group, Antje Lindenmeyer, Punith Kempegowda
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
ObjectiveTo understand and explore the perceptions and opinions of women with polycystic ovary syndrome (PCOS) and further delineate the variations across age and ethnicity.DesignQualitative survey focussed on lived experiences of people with PCOS. P
Externí odkaz:
https://doaj.org/article/05582af44f4044388c4db218520c4034
Autor:
Anuradhaa Subramanian, Siang Ing Lee, Katherine Phillips, Konstantinos A. Toulis, Punith Kempegowda, Michael W. O’Reilly, Nicola J. Adderley, Shakila Thangaratinam, Wiebke Arlt, Krishnarajah Nirantharakumar
Publikováno v:
BMC Medicine, Vol 20, Iss 1, Pp 1-13 (2022)
Abstract Background Polycystic ovary syndrome (PCOS) affects up to one in five women of childbearing age. Observational studies assessing the association between maternal PCOS and adverse obstetric outcomes have reported varying results, depending on
Externí odkaz:
https://doaj.org/article/47821d0f7f3f4333ac50aa2eba4e178c
Autor:
Gar Mun Lau, Mirna Elghobashy, Mansi Thanki, Shirley Ibegbulam, Pallavi Latthe, Caroline D. T. Gillett, Michael W. O’Reilly, Wiebke Arlt, Antje Lindenmeyer, Punith Kempegowda, PCOS SEva Working Group
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
IntroductionPCOS-related literature is mostly dominated by the medical perspective. However, the condition’s lifelong, far reaching, and multifaceted impacts highlight the importance to gain the perspectives from those with PCOS. Therefore, we perf
Externí odkaz:
https://doaj.org/article/6a3b72bf7ef148c28f892917a8fa8e5a
Autor:
Zarina Brady, Aoife Garrahy, Claire Carthy, Michael W. O’Reilly, Christopher J. Thompson, Mark Sherlock, Amar Agha, Mohsen Javadpour
Publikováno v:
BMC Endocrine Disorders, Vol 21, Iss 1, Pp 1-8 (2021)
Abstract Background Transsphenoidal surgery (TSS) to resect an adrenocorticotropic hormone (ACTH)-secreting pituitary adenoma is the first-line treatment for Cushing’s disease (CD), with increasing usage of endoscopic transsphenoidal (ETSS) techniq
Externí odkaz:
https://doaj.org/article/bea8c637837f47639d566b6cfe0bf168
Publikováno v:
Therapeutic Advances in Endocrinology and Metabolism, Vol 13 (2022)
Polycystic ovary syndrome (PCOS) is the most common endocrine condition affecting women. It has traditionally been viewed as a primarily reproductive disorder; however, it is increasingly recognized as a lifelong metabolic disease. Women with PCOS ar
Externí odkaz:
https://doaj.org/article/fdc6f9b051654ba7a85031b3b9208156
Autor:
Milad Darrat, Mohammad Binhussein, Alan Beausang, Clare Faul, Michael W O’Reilly, Mohsen Javadpour, Amar Agha
Publikováno v:
Endocrinology, Diabetes & Metabolism Case Reports, Vol 1, Iss 1, Pp 1-4 (2020)
Pituitary adenomas are the commonest sellar tumours. Pituitary metastases are very rare, with the most common primaries being breast and lung cancers. We report the case of an 83-year-old man with a history of breast carcinoma who presented with rece
Externí odkaz:
https://doaj.org/article/a6755edb3ca1485e8b250882d94469b8
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
To date, almost all solid malignancies have implicated insulin-like growth factor (IGF) signalling as a driver of tumour growth. However, the remarkable level of crosstalk between sex hormones, the IGF-1 receptor (IGF-1R) and its ligands IGF-1 and 2
Externí odkaz:
https://doaj.org/article/de530fe41a67448bab73cab72e587c85
Publikováno v:
European Journal of Endocrinology. 188:R98-R109
For many decades, the prevailing paradigm in endocrinology was that testosterone and 5α-dihydrotestosterone are the only potent androgens in the context of human physiology. The more recent identification of adrenal derived 11-oxygenated androgens a