Zobrazeno 1 - 10
of 289
pro vyhledávání: '"A W, Linnane"'
Publikováno v:
Journal of Controversies in Biomedical Research, Vol 1, Iss 1, Pp 23-27 (2015)
The production of intracellular reactive oxygen species and reactive nitrogen species has long been proposed as leading to the random deleterious modification of macromolecules (i.e., nucleic acids, proteins) with an associated progressive developmen
Externí odkaz:
https://doaj.org/article/4fc4c464a3f344608101a16f468a7b06
Autor:
Luis Vitetta, Rachel Manuel, Joyce Yusi Zhou, Anthony W. Linnane, Sean Hall, Samantha Coulson
Publikováno v:
Pharmaceuticals, Vol 7, Iss 9, Pp 954-989 (2014)
At the time of birth, humans experience an induced pro-inflammatory beneficial event. The mediators of this encouraged activity, is a fleet of bacteria that assault all mucosal surfaces as well as the skin. Thus initiating effects that eventually pro
Externí odkaz:
https://doaj.org/article/34429632ab824e0f9d886854427662c0
Publikováno v:
Toxins, Vol 5, Iss 11, Pp 2042-2057 (2013)
A host of compounds are retained in the body of uremic patients, as a consequence of progressive renal failure. Hundreds of compounds have been reported to be retention solutes and many have been proven to have adverse biological activity, and recogn
Externí odkaz:
https://doaj.org/article/5396b38c9ab44d40874e4bec6ca82fe3
Publikováno v:
Pathogens, Vol 2, Iss 4, Pp 606-626 (2013)
Natural medicines are an attractive option for patients diagnosed with common and debilitating musculoskeletal diseases such as Osteoarthritis (OA) or Rheumatoid Arthritis (RA). The high rate of self-medication with natural products is due to (1) lac
Externí odkaz:
https://doaj.org/article/f4024794060842e99d208f1b9db09bba
Autor:
Paul P. Masci, Caroline Airey, Janet Schloss, Maree Colosimo, Anthony W. Linnane, Luis Vitetta
Publikováno v:
Supportive Care in Cancer. 25:195-204
© 2016, Springer-Verlag Berlin Heidelberg. Introduction: Chemotherapy-induced peripheral neuropathy (CIPN) is a debilitating side effect resulting from neurotoxic chemotherapeutic agents. This study aimed to assess the efficacy and safety of an oral
Autor:
Anthony W. Linnane, Luis Vitetta
Publikováno v:
Inflammopharmacology. 22:69-72
The formations of reactive oxygen species (ROS) and reactive nitrogen species (RNS) have long been considered as major contributors to the dysregulation of the inflammatory response. Reactive oxygen species and RNS productions often are reported to b
Publikováno v:
Pathogens
Pathogens, Vol 2, Iss 4, Pp 606-626 (2013)
Pathogens, Vol 2, Iss 4, Pp 606-626 (2013)
Natural medicines are an attractive option for patients diagnosed with common and debilitating musculoskeletal diseases such as Osteoarthritis (OA) or Rheumatoid Arthritis (RA). The high rate of self-medication with natural products is due to (1) lac
Autor:
Anthony W. Linnane
Publikováno v:
IUBMB Life. 62:527-530
Age-related decline in stress responses of human myocardium may not be explained by changes in mtDNA
Autor:
Ruchong Ou, Franklin L. Rosenfeldt, Francis Miller, Chunfang Zhang, Phillip Nagley, Vincent W.S. Liu, Salvatore Pepe, Justin A. Mariani, Anthony W. Linnane
Publikováno v:
Mechanisms of Ageing and Development. 130:742-747
Elderly patients undergoing cardiac surgery are more likely to suffer postoperative heart failure than younger patients. This phenomenon is mirrored by an age-related loss of mitochondrial function and by an in vitro loss of myocardial contractile fo
Autor:
Anthony W. Linnane, Hayden Eastwood
Publikováno v:
Annals of the New York Academy of Sciences. 1067:47-55
The overarching role of coenzyme Q10 in gene regulation, bioenergy formation, cellular redox poise regulation, and hydrogen peroxide formation is presented. Coenzyme Q10 has a central role acting as a prooxidant in the generation of H2O2. Contrary to