Zobrazeno 1 - 10
of 567
pro vyhledávání: '"A W, Kopf"'
Autor:
Ben Schneider, Katrina W. Kopf, Emma Mason, Maggie Dawson, David Coronado Escobar, Susan M. Majka
Publikováno v:
Pulmonary Circulation, Vol 13, Iss 3, Pp n/a-n/a (2023)
Abstract Pulmonary vascular dysfunction is characterized by remodeling and loss of microvessels in the lung and is a major manifestation of chronic lung diseases (CLD). In murine models of CLD, the small arterioles and capillaries are the first and m
Externí odkaz:
https://doaj.org/article/de6ad536960d4185aaa46beb58df8ece
Autor:
Elizabeth F Redente, Katrina W Kopf, Ali N Bahadur, Annette Robichaud, Lennart K Lundblad, Lindsay T McDonald
Publikováno v:
PLoS ONE, Vol 18, Iss 2, p e0281452 (2023)
The advent of micro-computed tomography (microCT) has provided significant advancement in our ability to generate clinically relevant assessments of lung health and disease in small animal models. As microCT use to generate outcomes analysis in pulmo
Externí odkaz:
https://doaj.org/article/9fb76362416949ed9c978530522b9132
Autor:
Alicia N. Rizzo, Sarah M. Haeger, Kaori Oshima, Yimu Yang, Alison M. Wallbank, Ying Jin, Marie Lettau, Lynda A. McCaig, Nancy E. Wickersham, J. Brennan McNeil, Igor Zakharevich, Sarah A. McMurtry, Christophe J. Langouët-Astrié, Katrina W. Kopf, Dennis R. Voelker, Kirk C. Hansen, Ciara M. Shaver, V. Eric Kerchberger, Ryan A. Peterson, Wolfgang M. Kuebler, Matthias Ochs, Ruud A.W. Veldhuizen, Bradford J. Smith, Lorraine B. Ware, Julie A. Bastarache, Eric P. Schmidt
Publikováno v:
JCI Insight, Vol 7, Iss 2 (2022)
Acute respiratory distress syndrome (ARDS) is a common cause of respiratory failure yet has few pharmacologic therapies, reflecting the mechanistic heterogeneity of lung injury. We hypothesized that damage to the alveolar epithelial glycocalyx, a lay
Externí odkaz:
https://doaj.org/article/31aa2a1550884c5a8f8b113a7914671a
Autor:
Farida Ahangari, Christine Becker, Daniel G. Foster, Maurizio Chioccioli, Meghan Nelson, Keriann Beke, Xing Wang, Aurelien Justet, Taylor Adams, Benjamin Readhead, Carly Meador, Kelly Correll, Loukia N. Lili, Helen M. Roybal, Kadi-Ann Rose, Shuizi Ding, Thomas Barnthaler, Natalie Briones, Giuseppe DeIuliis, Jonas C. Schupp, Qin Li, Norihito Omote, Yael Aschner, Lokesh Sharma, Katrina W. Kopf, Björn Magnusson, Ryan Hicks, Anna Backmark, Charles S. Dela Cruz, Ivan Rosas, Leslie P. Cousens, Joel T. Dudley, Naftali Kaminski, Gregory P. Downey
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 206:1463-1479
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f4ff1d88506d695f84699d6c88253f8e
https://doi.org/10.1164/rccm.202010-3832oc
https://doi.org/10.1164/rccm.202010-3832oc
Autor:
Katrina W. Kopf, Julie W. Harral, Emily A. Staker, Megan E. Summers, Irina Petrache, Vitaly Kheyfets, David C. Irwin, Susan M. Majka
Publikováno v:
Pulmonary Circulation, Vol 10 (2020)
Pulmonary hypertension may arise as a complication of chronic lung disease typically associated with tissue hypoxia, as well as infectious agents or injury eliciting a type 2 immune response. The onset of pulmonary hypertension in this setting (class
Externí odkaz:
https://doaj.org/article/5964050858144c489d71a1ec34be4ad0
Autor:
Patrick S. Hume, Jazalle McClendon, Katrina W. Kopf, Julie W. Harral, Joanna M. Poczobutt, Alexandra L. McCubbrey, Bradford J. Smith, Peter M. Henson, Susan M. Majka, Irina Petrache, William J. Janssen
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 323:L391-L399
The pathogenesis of chronic obstructive pulmonary disease (COPD), a prevalent disease primarily caused by cigarette smoke exposure, is incompletely elucidated. Studies in humans and mice have suggested that hypoxia-inducible factor-1α (HIF-1α) may
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3b4e0cbf8b8ed9730a30f9a5660570a
https://doi.org/10.1152/ajplung.00491.2021
https://doi.org/10.1152/ajplung.00491.2021
Autor:
Yael Aschner, Kelly A. Correll, Keriann M. Beke, Daniel G. Foster, Helen M. Roybal, Meghan R. Nelson, Carly L. Meador, Matthew Strand, Kelsey C. Anderson, Camille M. Moore, Paul R. Reynolds, Katrina W. Kopf, Ellen L. Burnham, Gregory P. Downey
Publikováno v:
Am J Physiol Lung Cell Mol Physiol
The acute respiratory distress syndrome (ARDS) is a major healthcare problem, accounting for significant mortality and long-term disability. Approximately 25% of patients with ARDS will develop an overexuberant fibrotic response, termed fibroprolifer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fa08fc7732d4e28a737d67dcf8eb6d6
https://europepmc.org/articles/PMC9255711/
https://europepmc.org/articles/PMC9255711/
Autor:
Harry A Smith, Elysia Min, Kent Riemondy, Max A. Seibold, Brian J. Day, Katrina W. Kopf, Reena Berman, Jie Huang, Gregory P. Downey, Cecile S. Rose, Hong Wei Chu
Publikováno v:
Toxicol Sci
Upon returning from deployment to Afghanistan, a substantial number of U.S. military personnel report deployment-related lung disease (DRLD) symptoms, including those consistent with an asthma-like airways disease. DRLD is thought to be caused by pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1756dbebe0541f1956f08b65412d4772
https://doi.org/10.1093/toxsci/kfab065
https://doi.org/10.1093/toxsci/kfab065
Autor:
Farida Ahangari, Christine Becker, Daniel G. Foster, Maurizio Chioccioli, Meghan Nelson, Keriann Beke, Xing Wang, Benjamin Readhead, Carly Meador, Kelly Correll, Loukia Lili, Helen M. Roybal, Kadi-Ann Rose, Shuizi Ding, Thomas Barnthaler, Natalie Briones, Giuseppe Deluliis, Jonas C. Schupp, Qin Li, Norihito Omote, Yael Aschner, Katrina W. Kopf, Björn Magnusson, Ryan Hicks, Anna Backmark, Leslie P. Cousens, Joel T. Dudley, Naftali Kaminski, Gregory P. Downey
Idiopathic Pulmonary Fibrosis (IPF) is a chronic, progressive, and often fatal disorder. Two FDA approved anti-fibrotic drugs, nintedanib and pirfenidone, slow the rate of decline in lung function, but responses are variable and side effects are comm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::efdaa42632cbc2204f92aadf099cae97
https://doi.org/10.1101/2022.01.04.474955
https://doi.org/10.1101/2022.01.04.474955
Autor:
K.M. Beke, Daniel Foster, K.A. Correll, Matthew Strand, Yael Aschner, K. W. Kopf, Gregory P. Downey, H.M. Roybal, Paul R. Reynolds, Ellen L. Burnham, C. M. Moore
Publikováno v:
TP113. TP113 ACUTE LUNG INJURY AND REPAIR.
Rationale: Acute Respiratory Distress Syndrome (ARDS) is a major healthcare issue resulting in high morbidity and mortality. Up to 25% of patients with ARDS will develop pathological fibrosis, termed Fibroproliferative ARDS (FP-ARDS). In this subset
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::37625d50d9afc3f2fea3935f0182ba69
https://doi.org/10.1164/ajrccm-conference.2021.203.1_meetingabstracts.a4373
https://doi.org/10.1164/ajrccm-conference.2021.203.1_meetingabstracts.a4373