Zobrazeno 1 - 10
of 79
pro vyhledávání: '"A W, Hutcheon"'
Autor:
Andrew W. Hutcheon, Ashok Segar, Edna Simpson, T. K. Sarkar, Steven D. Heys, Leslie G. Walker, Keith N. Ogston, Oleg Eremin, Mary B. Walker, Antoine K. Ah-See
Publikováno v:
The Breast. 18:17-25
Eighty women undergoing multimodality treatment for large (>4cm) or locally advanced (T3, T4, Tx, N2), breast cancers participated in a randomised controlled trial (RCT) to evaluate the immuno-modulatory effects of relaxation training and guided imag
Autor:
Alemu Fite, Andrew Craig Schofield, Marie Goua, Steven D. Heys, K. W. Wahle, Andrew W. Hutcheon
Publikováno v:
Prostaglandins, Leukotrienes and Essential Fatty Acids. 77:87-96
Response rates of tumours to docetaxel (DOCT) are 45-60% in advanced breast cancer but problems associated with side effects, drug resistance and high costs occur. Conjugated linoleic acids (CLAs) also have anti-tumorigenic activity that elicits simi
Autor:
Steven D. Heys, Scott Ian Kay Semple, Andrew Welch, Thomas William Redpath, Fiona J. Gilbert, Trevor Ahearn, A. W. Hutcheon, Roger T. Staff
Publikováno v:
Annals of Oncology. 17:1393-1398
Background: The aim of the study was to investigate whether pre-therapy vascular delivery assessment [using dynamic contrast enhanced magnetic resonance imaging (DCE-MRI)] can predict reduction in breast cancer metabolism [detected using 2-[ 18 F] fl
Autor:
T. K. Sarkar, Steven D. Heys, Keith N. Ogston, Andrew Craig Schofield, Iain D. Miller, A. W. Hutcheon, Shailesh Chaturvedi, Catherine McLaren
Publikováno v:
Breast Cancer Research and Treatment. 93:151-158
This study aimed to evaluate patterns of local and distant disease recurrence in patients having primary chemotherapy and compared patterns of relapse in patients with a complete pathological response with those who had residual breast disease. This
Publikováno v:
Breast Cancer Research and Treatment. 90:169-185
Primary chemotherapy achieves high clinical response rates and facilitates breast conservation in many patients with large and locally advanced breast cancer. It may also serve to indicate responsiveness to chemotherapeutic agents. A pathological com
Publikováno v:
Expert Opinion on Pharmacotherapy. 5:2147-2157
Developments in the role of adjuvant and neoadjuvant chemotherapy for the treatment of patients with breast cancer have focused on the taxes, in particular, docetaxel. This paper discusses the rationale for the introduction of docetaxel into the mana
Autor:
Trevor Ahearn, Scott Ian Kay Semple, Fiona J. Gilbert, E Smyth, Shailesh Chaturvedi, Thomas William Redpath, Roger T. Staff, Andrew W. Hutcheon, Steven D. Heys, Andrew Welch
Publikováno v:
European Radiology. 14:2038-2045
The objective of this study was to investigate the relationship between vascular and metabolic characteristics of breast tumours in vivo, using contrast-enhanced dynamic MRI and 2-[(18)F] fluoro-2-deoxy- d-glucose (FDG) PET imaging. Twenty patients w
Autor:
S. Payne, Andrew Craig Schofield, Andrew W. Hutcheon, Steven D. Heys, Iain D. Miller, E. Pavlidou, Andreas Spyrantis, Keith N. Ogston, T. K. Sarkar
Publikováno v:
Breast Cancer Research and Treatment. 86:181-189
Purpose. Primary chemotherapy is commonly used in patients with breast cancer to downstage the primary tumour prior to surgery. There is a need to establish, prior to commencement of chemotherapy, predictors of clinical and pathological response, whi
Autor:
Iain D. Miller, T. K. Sarkar, A. W. Hutcheon, S. Payne, Andrew Craig Schofield, Steven D. Heys, Keith N. Ogston, Ian C. Smith
Publikováno v:
The Breast. 12:320-327
The clinical and complete pathological response of a primary breast cancer to chemotherapy has been shown to be an important prognostic for survival. However, the majority of patients do not experience a complete pathological response to primary chem
Autor:
Simon Payne, A. W. Hutcheon, Ian D. Miller, Steven D. Heys, Stuart McIntosh, T. K. Sarkar, Keith N Ogston
Publikováno v:
The American Journal of Surgery. 185:525-531
Background Primary chemotherapy is being given in the treatment of large and locally advanced breast cancers, but a major concern is local relapse after therapy. This paper has examined patients treated with primary chemotherapy and surgery (either b