Zobrazeno 1 - 10
of 422
pro vyhledávání: '"A W, Griffioen"'
Autor:
Battuja Dugershaw‐Kurzer, Jonas Bossart, Marija Buljan, Yvette Hannig, Sarah Zehnder, Govind Gupta, Vera M. Kissling, Patrycja Nowak‐Sliwinska, Judy R. vanBeijnum, Arjan W. Griffioen, Stefan Masjosthusmann, Etta Zühr, Ellen Fritsche, René Hornung, Thomas Rduch, Tina Buerki‐Thurnherr
Publikováno v:
Advanced Science, Vol 11, Iss 28, Pp n/a-n/a (2024)
Abstract Exposure to nanoparticles (NPs) in pregnancy is increasingly linked to adverse effects on embryo‐fetal development and health later in life. However, the developmental toxicity mechanisms of NPs are largely unknown, in particular potential
Externí odkaz:
https://doaj.org/article/2a31beb452ae480abf4e8493d6d513f5
Autor:
Mafalda Antunes-Ferreira, Silvia D’Ambrosi, Mohammad Arkani, Edward Post, Sjors G. J. G. In ‘t Veld, Jip Ramaker, Kenn Zwaan, Ece Demirel Kucukguzel, Laurine E. Wedekind, Arjan W. Griffioen, Mirjam Oude Egbrink, Marijke J. E. Kuijpers, Daan van den Broek, David P. Noske, Koen J. Hartemink, Siamack Sabrkhany, Idris Bahce, Nik Sol, Harm-Jan Bogaard, Danijela Koppers-Lalic, Myron G. Best, Thomas Wurdinger
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract Liquid biopsy approaches offer a promising technology for early and minimally invasive cancer detection. Tumor-educated platelets (TEPs) have emerged as a promising liquid biopsy biosource for the detection of various cancer types. In this s
Externí odkaz:
https://doaj.org/article/9358e61d08a441cdb79204397fabd108
Autor:
Judy R. van Beijnum, Elisabeth J. M. Huijbers, Karlijn van Loon, Athanasios Blanas, Parvin Akbari, Arno Roos, Tse J. Wong, Stepan S. Denisov, Tilman M. Hackeng, Connie R. Jimenez, Patrycja Nowak-Sliwinska, Arjan W. Griffioen
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-20 (2022)
The pro-tumorigenic effects of vimentin have been attributed to intracellular functions in tumour cells so far. Here, the authors show that tumour endothelial cells can secrete vimentin as a pro-angiogenic factor and that targeting of vimentin can be
Externí odkaz:
https://doaj.org/article/940243d65bf0461c97115d8cd768c41f
Autor:
Lucía Sanjurjo, Iris A. Schulkens, Pauline Touarin, Roy Heusschen, Ed Aanhane, Kitty C. M. Castricum, Tanja D. De Gruijl, Ulf J. Nilsson, Hakon Leffler, Arjan W. Griffioen, Latifa Elantak, Rory R. Koenen, Victor L. J. L. Thijssen
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-11 (2021)
Sanjurjo et al investigate the role of galectins in immunomodulation, reporting that chemokines can control galectin immunomodulatory function through a mechanism involving galectin-chemokine binding pairs. Specifically, the authors find that CXCL4 b
Externí odkaz:
https://doaj.org/article/c68df428db944ead902027a22af36904
Autor:
Siamack Sabrkhany, Marijke J.E. Kuijpers, Sander M.J. van Kuijk, Arjan W. Griffioen, Mirjam G.A. oude Egbrink
Publikováno v:
Haematologica, Vol 108, Iss 6 (2022)
Externí odkaz:
https://doaj.org/article/bd013716a69b4ea7864b206ff17cc434
Autor:
Athanasios Blanas, Haiko Karsjens, Aafke de Ligt, Elisabeth J.M. Huijbers, Karlijn van Loon, Stepan S. Denisov, Canan Durukan, Diederik J.M. Engbersen, Jan Groen, Sven Hennig, Tilman M. Hackeng, Judy R. van Beijnum, Arjan W. Griffioen
Publikováno v:
iScience, Vol 25, Iss 8, Pp 104719- (2022)
Summary: Poor immunogenicity of critical epitopes can hamper vaccine efficacy. To boost immune recognition of non- or low-immunogenic antigens, we developed a vaccine platform based on the conjugation of a target protein to a chimeric designer peptid
Externí odkaz:
https://doaj.org/article/1255ada1fb7443d9a31a721694925fe9
Autor:
Emma E. Don, Mei-An Middelkoop, Wouter J. K. Hehenkamp, Velja Mijatovic, Arjan W. Griffioen, Judith A. F. Huirne
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 8, p 7011 (2023)
Uterine fibroids are the most common benign tumors in women, with abnormal uterine bleeding (AUB) as the main reported symptom. Additionally, an association between fibroids and infertility has been established, especially if the fibroid protrudes in
Externí odkaz:
https://doaj.org/article/d2d7d2c9247044019ee1af7d165a09cc
Autor:
Marloes Zoetemelk, George M. Ramzy, Magdalena Rausch, Thibaud Koessler, Judy R. vanBeijnum, Andrea Weiss, Valentin Mieville, Sander R. Piersma, Richard R. deHaas, Céline Delucinge‐Vivier, Axel Andres, Christian Toso, Alexander A. Henneman, Simone Ragusa, Tatiana V. Petrova, Mylène Docquier, Thomas A. McKee, Connie R. Jimenez, Youssef Daali, Arjan W. Griffioen, Laura Rubbia‐Brandt, Pierre‐Yves Dietrich, Patrycja Nowak‐Sliwinska
Publikováno v:
Molecular Oncology, Vol 14, Iss 11, Pp 2894-2919 (2020)
The current standard of care for colorectal cancer (CRC) is a combination of chemotherapeutics, often supplemented with targeted biological drugs. An urgent need exists for improved drug efficacy and minimized side effects, especially at late‐stage
Externí odkaz:
https://doaj.org/article/95a558b6cae1422989a521f96cb74001
Autor:
Bianca Cioni, Anniek Zaalberg, Judy R. van Beijnum, Monique H. M. Melis, Johan van Burgsteden, Mauro J. Muraro, Erik Hooijberg, Dennis Peters, Ingrid Hofland, Yoni Lubeck, Jeroen de Jong, Joyce Sanders, Judith Vivié, Henk G. van der Poel, Jan Paul de Boer, Arjan W. Griffioen, Wilbert Zwart, Andries M. Bergman
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-17 (2020)
Anti-androgen therapy inhibits prostate cancer (PC) progression, and is thought to act directly on cancer cells. Here the authors show that androgen receptor is expressed on normal and PC-associated macrophages, and its stimulation alters macrophage
Externí odkaz:
https://doaj.org/article/3be95a4024404f56acd7fe8a4155f96c
Autor:
Marissa J. Harmsen, Arda Arduç, Maaike C. G. Bleeker, Lynda J. M. Juffermans, Arjan W. Griffioen, Ekaterina S. Jordanova, Judith A. F. Huirne
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 15, p 8434 (2022)
There is evidence for increased angiogenesis in the (ectopic) endometrium of adenomyosis patients under the influence of vascular endothelial growth factor (VEGF). VEGF stimulates both angiogenesis and lymph-angiogenesis. However, information on lymp
Externí odkaz:
https://doaj.org/article/94bbb0bf27a24e9cb20cad64162f8d99