Zobrazeno 1 - 10
of 23
pro vyhledávání: '"A W, Giuliano"'
Autor:
John Greene, Noa Kopplin, Jack Roireau, Mark Bezpalko, Scott Kassel, Michael W. Giuliano, Robert Giuliano
Publikováno v:
Acta Crystallographica Section E: Crystallographic Communications, Vol 76, Iss 5, Pp 761-764 (2020)
The pyranopyran amide (2S,4aR,8aR)-6-oxo-2,4a,6,8a-tetrahydropyrano[3,2-b]pyran-2-carboxamide, C9H9NO4, 3, was prepared by a chemoselective hydration of the corresponding nitrile, 2, using a heterogeneous catalytic method based on copper(II) supporte
Externí odkaz:
https://doaj.org/article/c687c4449be94fa7b5d4b29c0f20ad85
Autor:
Rachel E. Wilkinson, Katelyn N. Kraichely, Cecilia M. Hendy, Lauren E. Buchanan, Stuart Parnham, Michael W. Giuliano
Publikováno v:
Biochemical and Biophysical Research Communications. 626:121-128
Human galanin is a 30-residue neuropeptide targeted for development of analgesics, antidepressants, and anticonvulsants. While previous work from our group and others has already produced significant insights into galanin's N-terminal region, no exta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7352d6cf5dfc974381dbd3a1a9f22f26
https://doi.org/10.1016/j.bbrc.2022.08.032
https://doi.org/10.1016/j.bbrc.2022.08.032
Autor:
Katelyn N. Kraichely, Sarah E. Clinkscales, Cecilia M. Hendy, Eric A. Mendoza, Stuart Parnham, Michael W. Giuliano
Publikováno v:
Biochemistry. 61:1151-1166
The neuropeptide galanin has a 35-year history as an intriguing target in drug design owing to its implication as a potential anticonvulsant and neuronal trophic factor among many other therapeutically interesting functions including analgesia and mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d02e9cabbab2a425423b5dd8adcaf8a1
https://doi.org/10.1021/acs.biochem.2c00141
https://doi.org/10.1021/acs.biochem.2c00141
Autor:
Jack H. Roireau, Scott Kassel, Robert M. Giuliano, Michael W. Giuliano, Mark W. Bezpalko, John Greene, Noa Kopplin
Publikováno v:
Acta Crystallographica Section E: Crystallographic Communications, Vol 76, Iss 5, Pp 761-764 (2020)
Acta Crystallographica Section E: Crystallographic Communications
Acta Crystallographica Section E: Crystallographic Communications
(2S,4aR,8aR)-6-Oxo-2,4a,6,8a-tetrahydropyrano[3,2-b]pyran-2-carboxamide, a potentially effective antibacterial agent, was prepared by a chemoselective hydration of the corresponding nitrile using a heterogeneous catalytic method based on copper
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::934667ecd92874c3d663d05f308a1402
https://doi.org/10.1107/s2056989020001292
https://doi.org/10.1107/s2056989020001292
Publikováno v:
The Journal of organic chemistry. 84(21)
We report the structural characterization of the μ-selective endogenous opioid endomorphin-1 (EM-1) via an array of nuclear magnetic resonance experiments in both aqueous conditions and, for the first time, in isotropic lipid bicelles, which mimic i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d70e049fedd41ad693065fee8df8ac7
https://pubmed.ncbi.nlm.nih.gov/31538782
https://pubmed.ncbi.nlm.nih.gov/31538782
Publikováno v:
Chemical Science. 7:4085-4090
High-throughput screening for asymmetric catalysts has stimulated an interest in optically-based enantiomeric-excess (ee) sensors, primarily for their improved time and cost efficiency when compared to the standard HPLC analysis. We present herein su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::752be82efb7ecc6bc73664f74945351d
https://doi.org/10.1039/c5sc04629g
https://doi.org/10.1039/c5sc04629g
Publikováno v:
Advanced Synthesis & Catalysis. 357:2301-2309
We report an approach to the asymmetric Baeyer-Villiger oxidation utilizing bioinformatics-inspired combinatorial screening for catalyst discovery. Scaled-up validation of our on-bead efforts with a circular dichroism-based assay of alcohols derived
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91856c05093bae62069880bf88c02011
https://doi.org/10.1002/adsc.201500230
https://doi.org/10.1002/adsc.201500230
Publikováno v:
Chem. Sci.. 5:4504-4511
We detail an investigation of a peptide-based catalyst (6) that is effective for the site- (>100 : 1 : 1) and enantioselective epoxidation (86% ee) of farnesol. Studies of the substrate scope exhibited by the catalyst are included, along with an expl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eeffa08869d4c80409448226c8c02d22
https://doi.org/10.1039/c4sc01440e
https://doi.org/10.1039/c4sc01440e
Autor:
Jeffrey D. Sole, Gary W. Norman, William K. Igo, John W. Edwards, Craig A. Harper, Patrick K. Devers, Roy L. Kirkpatrick, Harry Spiker, David A. Swanson, Michael H. Seamster, David A. Buehler, Thomas J. Allen, Scott T. Friedhoff, Brian C. Tefft, Daniel E. Figert, Dean F. Stauffer, William W. Giuliano, Steve Bittner, Dave E. Steffen, Darroch M. Whitaker
Publikováno v:
Wildlife Monographs. 168:1-36
The Appalachian Cooperative Grouse Research Project (ACGRP) was a multistate cooperative effort initiated in 1996 to investigate the apparent decline of ruffed grouse (Bonasa umbellus) and improve management throughout the central and southern Appala
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4014b7428896b1c1a16275cf4d246264
https://doi.org/10.2193/0084-0173.168
https://doi.org/10.2193/0084-0173.168
Publikováno v:
ChemInform. 46
We report an approach to the asymmetric Baeyer–Villiger oxidation utilizing bioinformatics-inspired combinatorial screening for catalyst discovery. Scaled-up validation of our on-bead efforts with a circular dichroism-based assay of alcohols derive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::621a9263864bad94e20aec83d5e0f457
https://doi.org/10.1002/chin.201546025
https://doi.org/10.1002/chin.201546025