Zobrazeno 1 - 10
of 56
pro vyhledávání: '"A W, Broekmans"'
Autor:
Renske M.T. ten Ham, Jarno Hoekman, Anke M. Hövels, Andre W. Broekmans, Hubert G.M. Leufkens, Olaf H. Klungel
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 11, Iss , Pp 121-130 (2018)
Advanced therapy medicinal products (ATMPs) hold promise as treatments for previously untreatable and high-burden diseases. Expectations are high and active company pipelines are observed, yet only 10 market authorizations were approved in Europe. Ou
Externí odkaz:
https://doaj.org/article/d1e10b2078114479a61d2de16d64634b
Autor:
Nicola Bedlington, Hans-Georg Eichler, André W. Broekmans, Richard J. Barker, Solange Corriol-Rohou, Alicia Granados, Ad Schuurman, Jacoline C. Bouvy, Yann Le Cam, Anna Bucsics, Francesca Cerreta
Publikováno v:
Nature Reviews Drug Discovery
'Adaptive' approaches to bringing drugs to market have been widely discussed in recent years. Here, we describe the evolution of the adaptive approach and of concepts developed by ADAPT SMART, a multi-stakeholder consortium funded by the European Inn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff5a3a5f611b6e4cbc6ff0074b38982e
https://doi.org/10.1038/nrd.2018.90
https://doi.org/10.1038/nrd.2018.90
Autor:
J.E.F. Zwart van Rijkom, I. Plug, Frits R. Rosendaal, Andre W. Broekmans, Hubert G. M. Leufkens
Publikováno v:
British Journal of Haematology. 119:332-341
In comparison with other biotechnology substitutions, the adoption of recombinant Factor VIII (rFVIII) has been relatively slow. We sent a postal questionnaire to all Dutch haemophilia patients and haemophilia-treating physicians, to determine which
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8ab29ec5bf7578e0d603e31f000b2799
https://doi.org/10.1046/j.1365-2141.2002.03903.x
https://doi.org/10.1046/j.1365-2141.2002.03903.x
Autor:
André J.A. Elferink, André W. Broekmans, Barbara J. van Zwieten, Roel van Strik, Witte J G Hoogendijk, Jitschak G. Storosum
Publikováno v:
Schizophrenia Bulletin, 28, 193-201. Oxford University Press
Schizophrenia bulletin, 28(2), 193-201. Oxford University Press
Schizophrenia bulletin, 28(2), 193-201. Oxford University Press
In this article we report on a meta-analysis of the published studies of amisulpride conducted in order to demonstrate efficacy on primary negative symptoms in schizophrenia. Four placebo-controlled studies were conducted in patients with predominant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51bf79774b8ecb187c5fd9faee7f9760
https://doi.org/10.1093/oxfordjournals.schbul.a006931
https://doi.org/10.1093/oxfordjournals.schbul.a006931
Autor:
André W, Broekmans, Peter G M, Mol
Publikováno v:
Nederlands tijdschrift voor geneeskunde. 158
Recent European legislation has provided new tools to enhance the overseeing of medicinal products in the postmarketing phase. Package leaflets of newly approved medicines contain a black inverted triangle as a signal for enhanced monitoring. The lea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2900afb2166d59b4182c1d907bc958a5
https://pubmed.ncbi.nlm.nih.gov/24846112
https://pubmed.ncbi.nlm.nih.gov/24846112
Autor:
Berthold P. R. Gersons, Wim van den Brink, Jitschak G. Storosum, André W. Broekmans, Barbara J. van Zwieten, Roel van Strik, André J.A. Elferink
Publikováno v:
European neuropsychopharmacology, 11(2), 173-180. Elsevier
The original data from the placebo-arms and the tricyclic-arms of all parallel randomized controlled three-arm studies, which had been conducted in the period 1979–1991 for a drug under development in order to obtain marketing authorization for the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4287fb94976c93fd985e7258e5b353a
https://doi.org/10.1016/s0924-977x(01)00083-9
https://doi.org/10.1016/s0924-977x(01)00083-9
Autor:
Hubert G. M. Leufkens, Jeannette van Rijkom, Daan J.A. Crommelin, Andre W. Broekmans, Frans F. H. Rutten
Publikováno v:
Health Policy. 47:255-274
Biotechnology is increasingly regarded as an important reservoir for the development of new and innovative, but generally expensive, pharmaceuticals. At the same time, concerns about cost containment have triggered a keen interest in evaluating and c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2532327641cf4ee9f1d625cea70c030
https://doi.org/10.1016/s0168-8510(99)00017-2
https://doi.org/10.1016/s0168-8510(99)00017-2
Autor:
Wim van den Brink, Barbara J. van Zwieten, Jitschak G. Storosum, Berthold P. R. Gersons, André W. Broekmans
Publikováno v:
American journal of psychiatry, 158(8), 1271-1275. American Psychiatric Association
The purpose of this study was to determine if fear of an increased risk of attempted suicide in placebo groups participating in placebo-controlled studies is an argument against the performance of placebo-controlled trials in studies of major depress
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbbd8d9dec22706098f83efa6317814b
https://pubmed.ncbi.nlm.nih.gov/11925327
https://pubmed.ncbi.nlm.nih.gov/11925327
Autor:
Frans F. H. Rutten, Jan J. V. Busschbach, Andre W. Broekmans, Jeannette E. F. Zwart-van Rijkom, Hubertus G. M. Leufkens
Publikováno v:
PharmacoEconomics. 18(2)
To investigate differences in attitudes, knowledge and actual use of economic evaluations in different groups of decision-makers, and to compare the results from the Netherlands with the overall European results of the European Network on Methodology
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::575f3d4d94733369aa094d317d43326c
https://pubmed.ncbi.nlm.nih.gov/11067649
https://pubmed.ncbi.nlm.nih.gov/11067649
Publikováno v:
Nederlands tijdschrift voor geneeskunde. 144(16)
The clinical criteria for admission of new drugs to the European common market have become more stringent in recent years. Increasingly often, the manufacturer is required to demonstrate that the new drug offers a clinically visible and relevant bene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::699b1587d5d7787d56d4f8b195ca9d6b
https://pubmed.ncbi.nlm.nih.gov/10812445
https://pubmed.ncbi.nlm.nih.gov/10812445